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1QVX
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SOLUTION STRUCTURE OF THE FAT DOMAIN OF FOCAL ADHESION KINASE
分子名称:Focal adhesion kinase 1
著者Gao, G., Prutzman, K.C., King, M.L., DeRose, E.F., London, R.E., Schaller, M.D., Campbell, S.L.
登録日2003-08-29
公開日2004-03-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase in Complex with a Paxillin LD Peptide: EVIDENCE FOR A TWO-SITE BINDING MODEL.
J.Biol.Chem., 279, 2004
1PV3
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NMR SOLUTION STRUCTURE OF THE AVIAN FAT-DOMAIN OF FOCAL ADHESION KINASE
分子名称:Focal adhesion kinase 1
著者Prutzman, K.C., Gao, G., King, M.L., Iyer, V.V., Mueller, G.A., Schaller, M.D., Campbell, S.L.
登録日2003-06-26
公開日2004-05-25
最終更新日2016-04-27
実験手法SOLUTION NMR
主引用文献The Focal Adhesion Targeting Domain of Focal Adhesion Kinase Contains a Hinge Region that Modulates Tyrosine 926 Phosphorylation.
STRUCTURE, 12, 2004
1TXD
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF LEUKEMIA-ASSOCIATED RHOGEF
分子名称:Rho guanine nucleotide exchange factor 12
著者Kristelly, R., Gao, G., Tesmer, J.J.
登録日2004-07-03
公開日2004-09-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
1X86
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF LEUKEMIA-ASSOCIATED RHOGEF IN COMPLEX WITH RHOA
分子名称:Rho guanine nucleotide exchange factor 12, Transforming protein RhoA, PHOSPHATE ION
著者Kristelly, R., Gao, G., Tesmer, J.J.
登録日2004-08-17
公開日2004-09-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
3U9G
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CRYSTAL STRUCTURE OF THE ZINC FINGER ANTIVIRAL PROTEIN
分子名称:Zinc finger CCCH-type antiviral protein 1, ZINC ION
著者Chen, S., Xu, Y., Zhang, K., Wang, X., Sun, J., Gao, G., Liu, Y.
登録日2011-10-18
公開日2012-03-14
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
Nat.Struct.Mol.Biol., 19, 2012
3V32
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CRYSTAL STRUCTURE OF MCPIP1 N-TERMINAL CONSERVED DOMAIN
分子名称:Ribonuclease ZC3H12A
著者Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
登録日2011-12-12
公開日2012-05-23
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
3V33
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CRYSTAL STRUCTURE OF MCPIP1 CONSERVED DOMAIN WITH ZINC-FINGER MOTIF
分子名称:Ribonuclease ZC3H12A
著者Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
登録日2011-12-12
公開日2012-05-23
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
3V34
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CRYSTAL STRUCTURE OF MCPIP1 CONSERVED DOMAIN WITH MAGNESIUM ION IN THE CATALYTIC CENTER
分子名称:Ribonuclease ZC3H12A, MAGNESIUM ION
著者Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
登録日2011-12-12
公開日2012-05-23
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
4MX1
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STRUCTURE OF RICIN A CHAIN BOUND WITH 2-AMINO-4-OXO-N-(2-(3-PHENYLUREIDO)ETHYL)-3,4-DIHYDROPTERIDINE-7-CARBOXAMIDE
分子名称:Ricin A chain, 2-amino-4-oxo-N-{2-[(phenylcarbamoyl)amino]ethyl}-3,4-dihydropteridine-7-carboxamide, SULFATE ION, ...
著者Robertus, J.D., Wiget, P.A., Manzano, L.A., Pruet, J.M., Gao, G., Saito, R., Jasheway, K.R., Monzingo, A.F., Anslyn, E.V.
登録日2013-09-25
公開日2014-01-15
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics.
Bioorg.Med.Chem.Lett., 23, 2013
4MX5
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STRUCTURE OF RICIN A CHAIN BOUND WITH BENZYL-(2-(2-AMINO-4-OXO-3,4-DIHYDROPTERIDINE-7-CARBOXAMIDO)ETHYL)CARBAMATE
分子名称:Ricin A chain, benzyl (2-{[(2-amino-4-oxo-3,4-dihydropteridin-7-yl)carbonyl]amino}ethyl)carbamate
著者Jasheway, K.R., Robertus, J.D., Wiget, P.A., Manzano, L.A., Pruet, J.M., Gao, G., Saito, R., Monzingo, A.F., Anslyn, E.V.
登録日2013-09-25
公開日2014-01-15
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics.
Bioorg.Med.Chem.Lett., 23, 2013
4WJA
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CRYSTAL STRUCTURE OF PAXX
分子名称:Uncharacterized protein C9orf142
著者Xing, M., Yang, M., Huo, W., Feng, F., Wei, L., Ning, S., Yan, Z., Li, W., Wang, Q., Hou, M., Dong, C., Guo, R., Gao, G., Ji, J., Lan, L., Liang, H., Xu, D.
登録日2014-09-29
公開日2015-03-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway.
Nat Commun, 6, 2015
6I2M
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CRYSTAL STRUCTURE OF VACCINIA VIRUS PROTEIN A55 BTB-BACK DOMAIN IN COMPLEX WITH HUMAN CULLIN-3 N-TERMINUS
分子名称:Kelch repeat and BTB domain-containing protein A55, Cullin-3
著者Gao, G., Graham, S.C.
登録日2018-11-01
公開日2019-01-23
最終更新日2019-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of cullin-3 (Cul3) ubiquitin ligase subversion by vaccinia virus protein A55.
J. Biol. Chem., 2019
6J9K
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APO-ACRIIC2
分子名称:AcrIIC2, MAGNESIUM ION
著者Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
登録日2019-01-23
公開日2019-03-06
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (2.234 Å)
主引用文献Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 2019
6J9L
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FNOBH+ACRIIC2
分子名称:AcrIIC2, HNH endonuclease family protein
著者Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
登録日2019-01-23
公開日2019-03-06
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 2019
6J9M
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NMEBH+ACRIIC2
分子名称:CRISPR-associated endonuclease Cas9, AcrIIC2
著者Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
登録日2019-01-23
公開日2019-03-06
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 2019
6J9N
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NMEHNH+ACRIIC3
分子名称:CRISPR-associated endonuclease Cas9, AcrIIC3
著者Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
登録日2019-01-23
公開日2019-03-06
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (2.606 Å)
主引用文献Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 2019
4NFB
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STRUCTURE OF PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR (PILR )
分子名称:Paired immunoglobulin-like type 2 receptor alpha
著者Lu, Q., Lu, G., Qi, J., Li, Y., Zhang, Y., Wang, H., Fan, Z., Yan, J., Gao, G.
登録日2013-10-31
公開日2014-05-28
最終更新日2014-09-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献PILR alpha and PILR beta have a siglec fold and provide the basis of binding to sialic acid
Proc.Natl.Acad.Sci.USA, 111, 2014
4KPQ
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STRUCTURE AND RECEPTOR BINDING SPECIFICITY OF THE HEMAGGLUTININ H13 FROM AVIAN INFLUENZA A VIRUS H13N6
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE
著者Lu, X., Qi, J., Shi, Y., Gao, G.
登録日2013-05-14
公開日2013-07-03
最終更新日2013-08-14
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
4KPS
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STRUCTURE AND RECEPTOR BINDING SPECIFICITY OF THE HEMAGGLUTININ H13 FROM AVIAN INFLUENZA A VIRUS H13N6
分子名称:Hemagglutinin, O-SIALIC ACID, BETA-D-GALACTOSE, ...
著者Lu, X., Qi, J., Shi, Y., Gao, G.
登録日2013-05-14
公開日2013-07-03
最終更新日2013-08-14
実験手法X-RAY DIFFRACTION (2.587 Å)
主引用文献Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
1D2B
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THE MMP-INHIBITORY, N-TERMINAL DOMAIN OF HUMAN TISSUE INHIBITOR OF METALLOPROTEINASES-1 (N-TIMP-1), SOLUTION NMR, 29 STRUCTURES
分子名称:TISSUE INHIBITOR OF METALLOPROTEINASES-1
著者Wu, B., Arumugam, S., Semenchenko, V., Brew, K., Van Doren, S.R.
登録日1999-09-22
公開日1999-12-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure of tissue inhibitor of metalloproteinases-1 implicates localized induced fit in recognition of matrix metalloproteinases.
J.Mol.Biol., 295, 2000
1WOF
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CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1
分子名称:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
著者Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Rao, Z.
登録日2004-08-18
公開日2005-08-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
1Z09
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SOLUTION STRUCTURE OF KM23
分子名称:Dynein light chain 2A, cytoplasmic
著者Ilangovan, U., Ding, W., Mulder, K., Hinck, A.P., Zuniga, J., Trbovich, J.A., Demeler, B., Groppe, J.C.
登録日2005-03-01
公開日2005-08-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure and Dynamics of the Homodimeric Dynein Light Chain km23.
J.Mol.Biol., 352 (2), 2005
2AMD
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CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N9
分子名称:3C-like proteinase, N-(3-FUROYL)-D-VALYL-L-VALYL-N~1~-((1R,2Z)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-D-LEUCINAMIDE
著者Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
登録日2005-08-09
公開日2005-09-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMP
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CRYSTAL STRUCTURE OF PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS MPRO IN COMPLEX WITH AN INHIBITOR N1
分子名称:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
著者Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
登録日2005-08-10
公開日2005-09-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMQ
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CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N3
分子名称:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
著者Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
登録日2005-08-10
公開日2005-09-13
最終更新日2015-12-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
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