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1QVX
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SOLUTION STRUCTURE OF THE FAT DOMAIN OF FOCAL ADHESION KINASE
Descriptor:Focal adhesion kinase 1
Authors:Gao, G., Prutzman, K.C., King, M.L., DeRose, E.F., London, R.E., Schaller, M.D., Campbell, S.L.
Deposit date:2003-08-29
Release date:2004-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase in Complex with a Paxillin LD Peptide: EVIDENCE FOR A TWO-SITE BINDING MODEL.
J.Biol.Chem., 279, 2004
1PV3
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NMR SOLUTION STRUCTURE OF THE AVIAN FAT-DOMAIN OF FOCAL ADHESION KINASE
Descriptor:Focal adhesion kinase 1
Authors:Prutzman, K.C., Gao, G., King, M.L., Iyer, V.V., Mueller, G.A., Schaller, M.D., Campbell, S.L.
Deposit date:2003-06-26
Release date:2004-05-25
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:The Focal Adhesion Targeting Domain of Focal Adhesion Kinase Contains a Hinge Region that Modulates Tyrosine 926 Phosphorylation.
STRUCTURE, 12, 2004
1TXD
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF LEUKEMIA-ASSOCIATED RHOGEF
Descriptor:Rho guanine nucleotide exchange factor 12
Authors:Kristelly, R., Gao, G., Tesmer, J.J.
Deposit date:2004-07-03
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
1X86
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF LEUKEMIA-ASSOCIATED RHOGEF IN COMPLEX WITH RHOA
Descriptor:Rho guanine nucleotide exchange factor 12, Transforming protein RhoA, PHOSPHATE ION
Authors:Kristelly, R., Gao, G., Tesmer, J.J.
Deposit date:2004-08-17
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
3U9G
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CRYSTAL STRUCTURE OF THE ZINC FINGER ANTIVIRAL PROTEIN
Descriptor:Zinc finger CCCH-type antiviral protein 1, ZINC ION
Authors:Chen, S., Xu, Y., Zhang, K., Wang, X., Sun, J., Gao, G., Liu, Y.
Deposit date:2011-10-18
Release date:2012-03-14
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
Nat.Struct.Mol.Biol., 19, 2012
3V32
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CRYSTAL STRUCTURE OF MCPIP1 N-TERMINAL CONSERVED DOMAIN
Descriptor:Ribonuclease ZC3H12A
Authors:Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
Deposit date:2011-12-12
Release date:2012-05-23
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
3V33
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CRYSTAL STRUCTURE OF MCPIP1 CONSERVED DOMAIN WITH ZINC-FINGER MOTIF
Descriptor:Ribonuclease ZC3H12A
Authors:Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
Deposit date:2011-12-12
Release date:2012-05-23
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
3V34
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CRYSTAL STRUCTURE OF MCPIP1 CONSERVED DOMAIN WITH MAGNESIUM ION IN THE CATALYTIC CENTER
Descriptor:Ribonuclease ZC3H12A, MAGNESIUM ION
Authors:Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
Deposit date:2011-12-12
Release date:2012-05-23
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
4MX1
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STRUCTURE OF RICIN A CHAIN BOUND WITH 2-AMINO-4-OXO-N-(2-(3-PHENYLUREIDO)ETHYL)-3,4-DIHYDROPTERIDINE-7-CARBOXAMIDE
Descriptor:Ricin A chain, 2-amino-4-oxo-N-{2-[(phenylcarbamoyl)amino]ethyl}-3,4-dihydropteridine-7-carboxamide, SULFATE ION, ...
Authors:Robertus, J.D., Wiget, P.A., Manzano, L.A., Pruet, J.M., Gao, G., Saito, R., Jasheway, K.R., Monzingo, A.F., Anslyn, E.V.
Deposit date:2013-09-25
Release date:2014-01-15
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics.
Bioorg.Med.Chem.Lett., 23, 2013
4MX5
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STRUCTURE OF RICIN A CHAIN BOUND WITH BENZYL-(2-(2-AMINO-4-OXO-3,4-DIHYDROPTERIDINE-7-CARBOXAMIDO)ETHYL)CARBAMATE
Descriptor:Ricin A chain, benzyl (2-{[(2-amino-4-oxo-3,4-dihydropteridin-7-yl)carbonyl]amino}ethyl)carbamate
Authors:Jasheway, K.R., Robertus, J.D., Wiget, P.A., Manzano, L.A., Pruet, J.M., Gao, G., Saito, R., Monzingo, A.F., Anslyn, E.V.
Deposit date:2013-09-25
Release date:2014-01-15
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics.
Bioorg.Med.Chem.Lett., 23, 2013
4WJA
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CRYSTAL STRUCTURE OF PAXX
Descriptor:Uncharacterized protein C9orf142
Authors:Xing, M., Yang, M., Huo, W., Feng, F., Wei, L., Ning, S., Yan, Z., Li, W., Wang, Q., Hou, M., Dong, C., Guo, R., Gao, G., Ji, J., Lan, L., Liang, H., Xu, D.
Deposit date:2014-09-29
Release date:2015-03-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway.
Nat Commun, 6, 2015
6I2M
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CRYSTAL STRUCTURE OF VACCINIA VIRUS PROTEIN A55 BTB-BACK DOMAIN IN COMPLEX WITH HUMAN CULLIN-3 N-TERMINUS
Descriptor:Kelch repeat and BTB domain-containing protein A55, Cullin-3
Authors:Gao, G., Graham, S.C.
Deposit date:2018-11-01
Release date:2019-01-23
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of cullin-3 (Cul3) ubiquitin ligase subversion by vaccinia virus protein A55.
J. Biol. Chem., 2019
6J9K
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APO-ACRIIC2
Descriptor:AcrIIC2, MAGNESIUM ION
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.234 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 2019
6J9L
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FNOBH+ACRIIC2
Descriptor:AcrIIC2, HNH endonuclease family protein
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 2019
6J9M
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NMEBH+ACRIIC2
Descriptor:CRISPR-associated endonuclease Cas9, AcrIIC2
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 2019
6J9N
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NMEHNH+ACRIIC3
Descriptor:CRISPR-associated endonuclease Cas9, AcrIIC3
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 2019
4NFB
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STRUCTURE OF PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR (PILR )
Descriptor:Paired immunoglobulin-like type 2 receptor alpha
Authors:Lu, Q., Lu, G., Qi, J., Li, Y., Zhang, Y., Wang, H., Fan, Z., Yan, J., Gao, G.
Deposit date:2013-10-31
Release date:2014-05-28
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:PILR alpha and PILR beta have a siglec fold and provide the basis of binding to sialic acid
Proc.Natl.Acad.Sci.USA, 111, 2014
4KPQ
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STRUCTURE AND RECEPTOR BINDING SPECIFICITY OF THE HEMAGGLUTININ H13 FROM AVIAN INFLUENZA A VIRUS H13N6
Descriptor:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE
Authors:Lu, X., Qi, J., Shi, Y., Gao, G.
Deposit date:2013-05-14
Release date:2013-07-03
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
4KPS
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STRUCTURE AND RECEPTOR BINDING SPECIFICITY OF THE HEMAGGLUTININ H13 FROM AVIAN INFLUENZA A VIRUS H13N6
Descriptor:Hemagglutinin, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Lu, X., Qi, J., Shi, Y., Gao, G.
Deposit date:2013-05-14
Release date:2013-07-03
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.587 Å)
Cite:Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
1D2B
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THE MMP-INHIBITORY, N-TERMINAL DOMAIN OF HUMAN TISSUE INHIBITOR OF METALLOPROTEINASES-1 (N-TIMP-1), SOLUTION NMR, 29 STRUCTURES
Descriptor:TISSUE INHIBITOR OF METALLOPROTEINASES-1
Authors:Wu, B., Arumugam, S., Semenchenko, V., Brew, K., Van Doren, S.R.
Deposit date:1999-09-22
Release date:1999-12-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of tissue inhibitor of metalloproteinases-1 implicates localized induced fit in recognition of matrix metalloproteinases.
J.Mol.Biol., 295, 2000
1WOF
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CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Rao, Z.
Deposit date:2004-08-18
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
1Z09
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SOLUTION STRUCTURE OF KM23
Descriptor:Dynein light chain 2A, cytoplasmic
Authors:Ilangovan, U., Ding, W., Mulder, K., Hinck, A.P., Zuniga, J., Trbovich, J.A., Demeler, B., Groppe, J.C.
Deposit date:2005-03-01
Release date:2005-08-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Dynamics of the Homodimeric Dynein Light Chain km23.
J.Mol.Biol., 352 (2), 2005
2AMD
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CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N9
Descriptor:3C-like proteinase, N-(3-FUROYL)-D-VALYL-L-VALYL-N~1~-((1R,2Z)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-D-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-09
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMP
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CRYSTAL STRUCTURE OF PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS MPRO IN COMPLEX WITH AN INHIBITOR N1
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-10
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMQ
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CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N3
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-10
Release date:2005-09-13
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
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