Author results

2B1X
  • Download 2b1x
  • View 2b1x
Molmil generated image of 2b1x
CRYSTAL STRUCTURE OF NAPHTHALENE 1,2-DIOXYGENASE FROM RHODOCOCCUS SP.
Descriptor:naphthalene dioxygenase large subunit, naphthalene dioxygenase small subunit, FE (III) ION, ...
Authors:Gakhar, L., Malik, Z.A., Allen, C.C., Lipscomb, D.A., Larkin, M.J., Ramaswamy, S.
Deposit date:2005-09-16
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Increased Thermostability of Rhodococcus sp. Naphthalene 1,2-Dioxygenase.
J.Bacteriol., 187, 2005
2B24
  • Download 2b24
  • View 2b24
Molmil generated image of 2b24
CRYSTAL STRUCTURE OF NAPHTHALENE 1,2-DIOXYGENASE FROM RHODOCOCCUS SP. BOUND TO INDOLE
Descriptor:naphthalene dioxygenase large subunit, naphthalene dioxygenase small subunit, FE (III) ION, ...
Authors:Gakhar, L., Malik, Z.A., Allen, C.C., Lipscomb, D.A., Larkin, M.J., Ramaswamy, S.
Deposit date:2005-09-16
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and Increased Thermostability of Rhodococcus sp. Naphthalene 1,2-Dioxygenase.
J.Bacteriol., 187, 2005
5JEN
  • Download 5jen
  • View 5jen
Molmil generated image of 5jen
CRYSTAL STRUCTURE OF THE ANTI-SIGMA FACTOR RSIV BOUND TO LYSOZYME
Descriptor:Anti-sigma-V factor RsiV, Lysozyme C, SODIUM ION, ...
Authors:Gakhar, L., Williams, K.B., Ellermeir, C.D.
Deposit date:2016-04-18
Release date:2016-09-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The anti-sigma factor RsiV is a receptor for lysozyme: The crystal structure of RsiV-lysozyme complex
To Be Published
3ODT
  • Download 3odt
  • View 3odt
Molmil generated image of 3odt
CRYSTAL STRUCTURE OF WD40 BETA PROPELLER DOMAIN OF DOA1
Descriptor:Protein DOA1, CALCIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Pashkova, N., Gakhar, L., Winistorfer, S.C., Yu, L., Ramaswamy, S., Piper, R.C.
Deposit date:2010-08-11
Release date:2010-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:WD40 Repeat Propellers Define a Ubiquitin-Binding Domain that Regulates Turnover of F Box Proteins.
Mol.Cell, 40, 2010
4JJY
  • Download 4jjy
  • View 4jjy
Molmil generated image of 4jjy
ALIX V DOMAIN
Descriptor:Programmed cell death 6-interacting protein
Authors:Pashkova, N., Gakhar, L., Yu, L., Piper, R.C.
Deposit date:2013-03-08
Release date:2013-06-19
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (6.503 Å)
Cite:The yeast alix homolog bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes.
Dev.Cell, 25, 2013
4JIO
  • Download 4jio
  • View 4jio
Molmil generated image of 4jio
BRO1 V DOMAIN AND UBIQUITIN
Descriptor:BRO1, Ubiquitin
Authors:Pashkova, N., Gakhar, L., Piper, R.C.
Deposit date:2013-03-06
Release date:2013-06-19
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The yeast alix homolog bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes.
Dev.Cell, 25, 2013
5U9A
  • Download 5u9a
  • View 5u9a
Molmil generated image of 5u9a
CRYSTAL STRUCTURE OF THE FKBP DOMAIN OF HUMAN ARYL HYDROCARBON RECEPTOR-INTERACTING PROTEIN-LIKE 1 (AIPL1)
Descriptor:Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)
Authors:Yadav, R.P., Gakhar, L., Liping, Y., Artemyev, N.O.
Deposit date:2016-12-15
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U9I
  • Download 5u9i
  • View 5u9i
Molmil generated image of 5u9i
CRYSTAL STRUCTURE OF THE FKBP DOMAIN OF HUMAN ARYL HYDROCARBON RECEPTOR-INTERACTING PROTEIN-LIKE 1 (AIPL1) COMPLEXED WITH S-FARNESYL-L-CYSTEINE METHYL ESTER
Descriptor:Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL
Authors:Yadav, R.P., Gakhar, L., Liping, Y., Artemyev, N.O.
Deposit date:2016-12-16
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U9J
  • Download 5u9j
  • View 5u9j
Molmil generated image of 5u9j
CRYSTAL STRUCTURE OF THE FKBP DOMAIN OF HUMAN ARYL HYDROCARBON RECEPTOR-INTERACTING PROTEIN-LIKE 1 (AIPL1) COMPLEXED WITH GERANYL GERANYL PYROPHOSHATE
Descriptor:Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), GERAN-8-YL GERAN, ISOPROPYL ALCOHOL, ...
Authors:Yadav, R.P., Gakhar, L., Liping, Y., Artemyev, N.O.
Deposit date:2016-12-16
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U9K
  • Download 5u9k
  • View 5u9k
Molmil generated image of 5u9k
CRYSTAL STRUCTURE OF V71F MUTANT OF THE FKBP DOMAIN OF HUMAN ARYL HYDROCARBON RECEPTOR-INTERACTING PROTEIN-LIKE 1 (AIPL1)
Descriptor:Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)
Authors:Yadav, R.P., Gakhar, L., Liping, Y., Artemyev, N.O.
Deposit date:2016-12-16
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V35
  • Download 5v35
  • View 5v35
Molmil generated image of 5v35
CRYSTAL STRUCTURE OF V71F MUTANT OF THE FKBP DOMAIN OF HUMAN ARYL HYDROCARBON RECEPTOR-INTERACTING PROTEIN-LIKE 1 (AIPL1) COMPLEXED WITH S-FARNESYL-L-CYSTEINE METHYL ESTER
Descriptor:Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL
Authors:Yadav, R.P., Gakhar, L., Liping, Y., Artemyev, N.O.
Deposit date:2017-03-06
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2HQW
  • Download 2hqw
  • View 2hqw
Molmil generated image of 2hqw
CRYSTAL STRUCTURE OF CA2+/CALMODULIN BOUND TO NMDA RECEPTOR NR1C1 PEPTIDE
Descriptor:Calmodulin, Glutamate NMDA receptor subunit zeta 1, CALCIUM ION
Authors:Akyol, Z., Gakhar, L., Sorensen, B.R., Hell, J.H., Shea, M.A.
Deposit date:2006-07-19
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The NMDA Receptor NR1 C1 Region Bound to Calmodulin: Structural Insights into Functional Differences between Homologous Domains.
Structure, 15, 2007
3GPM
  • Download 3gpm
  • View 3gpm
Molmil generated image of 3gpm
STRUCTURE OF THE TRIMERIC FORM OF THE E113G PCNA MUTANT PROTEIN
Descriptor:Proliferating cell nuclear antigen
Authors:Freudenthal, B.D., Gakhar, L., Ramaswamy, S., Washington, M.T.
Deposit date:2009-03-23
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009
3GPN
  • Download 3gpn
  • View 3gpn
Molmil generated image of 3gpn
STRUCTURE OF THE NON-TRIMERIC FORM OF THE E113G PCNA MUTANT PROTEIN
Descriptor:Proliferating cell nuclear antigen
Authors:Freudenthal, B.D., Gakhar, L., Ramaswamy, S., Washington, M.T.
Deposit date:2009-03-23
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009
3JWQ
  • Download 3jwq
  • View 3jwq
Molmil generated image of 3jwq
CRYSTAL STRUCTURE OF CHIMERIC PDE5/PDE6 CATALYTIC DOMAIN COMPLEXED WITH SILDENAFIL
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera, ZINC ION, ...
Authors:Barren, B., Gakhar, L., Muradov, H., Boyd, K.K., Ramaswamy, S., Artemyev, N.O.
Deposit date:2009-09-18
Release date:2009-10-13
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit
Embo J., 28, 2009
3JWR
  • Download 3jwr
  • View 3jwr
Molmil generated image of 3jwr
CRYSTAL STRUCTURE OF CHIMERIC PDE5/PDE6 CATALYTIC DOMAIN COMPLEXED WITH 3-ISOBUTYL-1-METHYLXANTHINE (IBMX) AND PDE6 GAMMA-SUBUNIT INHIBITORY PEPTIDE 70-87.
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ...
Authors:Barren, B., Gakhar, L., Muradov, H., Boyd, K.K., Ramaswamy, S., Artemyev, N.O.
Deposit date:2009-09-18
Release date:2009-10-13
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit
Embo J., 28, 2009
3L0W
  • Download 3l0w
  • View 3l0w
Molmil generated image of 3l0w
STRUCTURE OF SPLIT MONOUBIQUITINATED PCNA WITH UBIQUITIN IN POSITION TWO
Descriptor:Proliferating cell nuclear antigen, Monoubiquitinated Proliferating cell nuclear antigen
Authors:Freudenthal, B.D., Gakhar, L., Ramaswamy, S., Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
3L0X
  • Download 3l0x
  • View 3l0x
Molmil generated image of 3l0x
STRUCTURE OF SPLIT YEAST PCNA
Descriptor:Proliferating cell nuclear antigen
Authors:Freudenthal, B.D., Gakhar, L., Ramaswamy, S., Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
3L10
  • Download 3l10
  • View 3l10
Molmil generated image of 3l10
STRUCTURE OF SPLIT MONOUBIQUITINATED PCNA WITH UBIQUITIN IN POSITION ONE
Descriptor:Proliferating cell nuclear antigen, Monoubiquitinated Proliferating cell nuclear antigen
Authors:Freudenthal, B.D., Gakhar, L., Ramaswamy, S., Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
3PGE
  • Download 3pge
  • View 3pge
Molmil generated image of 3pge
STRUCTURE OF SUMOYLATED PCNA
Descriptor:SUMO-modified proliferating cell nuclear antigen, Proliferating cell nuclear antigen
Authors:Freudenthal, B.D., Brogie, J.E., Gakhar, L., Washington, T.
Deposit date:2010-11-01
Release date:2010-12-29
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen.
J.Mol.Biol., 406, 2011
3T95
  • Download 3t95
  • View 3t95
Molmil generated image of 3t95
CRYSTAL STRUCTURE OF LSRB FROM YERSINIA PESTIS COMPLEXED WITH AUTOINDUCER-2
Descriptor:Autoinducer 2-binding protein lsrB, (2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN
Authors:Kavanaugh, J.S., Gakhar, L., Horswill, A.R.
Deposit date:2011-08-02
Release date:2011-12-07
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of LsrB from Yersinia pestis complexed with autoinducer-2.
Acta Crystallogr.,Sect.F, 67, 2011
4ID3
  • Download 4id3
  • View 4id3
Molmil generated image of 4id3
CRYSTAL STRUCTURE OF THE BRCT DOMAIN OF S. CEREVISIAE REV1
Descriptor:DNA repair protein REV1
Authors:Pryor, J.M., Gakhar, L., Washington, M.T.
Deposit date:2012-12-11
Release date:2013-01-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9669 Å)
Cite:Structure and Functional Analysis of the BRCT Domain of Translesion Synthesis DNA Polymerase Rev1.
Biochemistry, 52, 2013
4JQW
  • Download 4jqw
  • View 4jqw
Molmil generated image of 4jqw
CRYSTAL STRUCTURE OF A COMPLEX OF NOD1 CARD AND UBIQUITIN
Descriptor:Nucleotide-binding oligomerization domain-containing protein 1, Polyubiquitin-C, PHOSPHATE ION
Authors:Ver Heul, A.M., Gakhar, L., Piper, R.C., Ramaswamy, S.
Deposit date:2013-03-20
Release date:2014-03-26
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a complex of NOD1 CARD and ubiquitin
Plos One, 9, 2014
4K2O
  • Download 4k2o
  • View 4k2o
Molmil generated image of 4k2o
THE STRUCTURE OF A TRIPLE MUTANT OF THE TIAM1 PH-CC-EX DOMAIN
Descriptor:T-lymphoma invasion and metastasis-inducing protein 1
Authors:Joshi, M., Gakhar, L., Fuentes, E.J.
Deposit date:2013-04-09
Release date:2013-07-10
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:High-resolution structure of the Tiam1 PHn-CC-Ex domain.
Acta Crystallogr.,Sect.F, 69, 2013
4K2P
  • Download 4k2p
  • View 4k2p
Molmil generated image of 4k2p
THE STRUCTURE OF A QUINTUPLE MUTANT OF THE TIAM1 PH-CC-EX DOMAIN
Descriptor:T-lymphoma invasion and metastasis-inducing protein 1, CALCIUM ION
Authors:Joshi, M., Gakhar, L., Fuentes, E.J.
Deposit date:2013-04-09
Release date:2013-07-10
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:High-resolution structure of the Tiam1 PHn-CC-Ex domain.
Acta Crystallogr.,Sect.F, 69, 2013
<12>