4P1W
 
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4P1N
 | | Crystal structure of Atg1-Atg13 complex | | Descriptor: | Atg1 tMIT, Atg13 MIM | | Authors: | Fujioka, Y, Noda, N.N. | | Deposit date: | 2014-02-27 | | Release date: | 2014-05-07 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of starvation-induced assembly of the autophagy initiation complex.
Nat.Struct.Mol.Biol., 21, 2014
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3A7O
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3A7P
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5JHF
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7F2X
 | | Crystal structure of MEK1 C121S mutant | | Descriptor: | MEK1 F11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Fujioka, Y, Noda, N.N. | | Deposit date: | 2021-06-15 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.007 Å) | | Cite: | Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Nat Commun, 13, 2022
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2LI5
 | | NMR structure of Atg8-Atg7C30 complex | | Descriptor: | Autophagy-related protein 8, Ubiquitin-like modifier-activating enzyme ATG7 | | Authors: | Kumeta, H, Satoo, K, Noda, N.N, Fujioka, Y, Ogura, K, Nakatogawa, H, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2011-08-23 | | Release date: | 2011-11-16 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis of Atg8 activation by a homodimeric E1, Atg7.
Mol.Cell, 44, 2011
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2K6Q
 | | LC3 p62 complex structure | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1 | | Authors: | Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2008-07-17 | | Release date: | 2008-09-02 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis of target recognition by ATG8/LC3 during selective autophagy
To be Published
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2KWC
 | | The NMR structure of the autophagy-related protein Atg8 | | Descriptor: | Autophagy-related protein 8 | | Authors: | Kumeta, H, Watanabe, M, Nakatogawa, H, Yamaguchi, M, Ogura, K, Adachi, W, Fujioka, Y, Noda, N.N, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2010-04-05 | | Release date: | 2010-05-12 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The NMR structure of the autophagy-related protein Atg8
J.Biomol.Nmr, 47, 2010
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1UGM
 | | Crystal Structure of LC3 | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3 | | Authors: | Sugawara, K, Suzuki, N.N, Fujioka, Y, Mizushima, N, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2003-06-16 | | Release date: | 2004-07-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8
Genes Cells, 9, 2004
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2JPE
 | | FHA domain of NIPP1 | | Descriptor: | Nuclear inhibitor of protein phosphatase 1 | | Authors: | Kumeta, H, Ogura, K, Fujioka, Y, Tanuma, N, Kikuchi, K, Inagaki, F. | | Deposit date: | 2007-05-07 | | Release date: | 2007-05-15 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The NMR structure of the NIPP1 FHA domain.
J.Biomol.Nmr, 40, 2008
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5AZG
 | | Crystal structure of LGG-1 complexed with a UNC-51 peptide | | Descriptor: | CADMIUM ION, Protein lgg-1, Serine/threonine-protein kinase unc-51 | | Authors: | Watanabe, Y, Fujioka, Y, Noda, N.N. | | Deposit date: | 2015-10-05 | | Release date: | 2015-12-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy.
Mol.Cell, 60, 2015
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5AZH
 | | Crystal structure of LGG-2 fused with an EEEWEEL peptide | | Descriptor: | EEEWEEL peptide,Protein lgg-2, MAGNESIUM ION | | Authors: | Watanabe, Y, Fujioka, Y, Noda, N.N. | | Deposit date: | 2015-10-05 | | Release date: | 2015-12-30 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy.
Mol.Cell, 60, 2015
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2CY7
 | | The crystal structure of human Atg4B | | Descriptor: | Cysteine protease APG4B | | Authors: | Sugawara, K, Suzuki, N.N, Fujioka, Y, Mizushima, N, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2005-07-05 | | Release date: | 2005-09-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for the Specificity and Catalysis of Human Atg4B Responsible for Mammalian Autophagy
J.Biol.Chem., 280, 2005
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1WZ3
 | | The crystal structure of plant ATG12 | | Descriptor: | autophagy 12b | | Authors: | Suzuki, N.N, Yoshimoto, K, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2005-02-22 | | Release date: | 2005-06-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structure of plant ATG12 and its biological implication in autophagy.
Autophagy, 1, 2005
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1Z9Q
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2CZO
 | | Solution Structure of the PX Domain of Bem1p | | Descriptor: | Bud emergence protein 1 | | Authors: | Maeda, A, Ogura, K, Horiuchi, M, Kumeta, H, Fujioka, Y, Inagaki, F. | | Deposit date: | 2005-07-14 | | Release date: | 2006-10-03 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the PX domain of Bem1p
To be Published
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1UEC
 | | Crystal structure of autoinhibited form of tandem SH3 domain of p47phox | | Descriptor: | Neutrophil cytosol factor 1 | | Authors: | Yuzawa, S, Suzuki, N.N, Fujioka, Y, Ogura, K, Sumimoto, H, Inagaki, F. | | Deposit date: | 2003-05-11 | | Release date: | 2003-05-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase
Genes Cells, 9, 2004
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3VX8
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3VX7
 | | Crystal structure of Kluyveromyces marxianus Atg7NTD-Atg10 complex | | Descriptor: | E1, E2 | | Authors: | Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. | | Deposit date: | 2012-09-11 | | Release date: | 2012-11-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.
Nat.Struct.Mol.Biol., 19, 2012
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3VX6
 | | Crystal structure of Kluyveromyces marxianus Atg7NTD | | Descriptor: | E1 | | Authors: | Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. | | Deposit date: | 2012-09-11 | | Release date: | 2012-11-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.
Nat.Struct.Mol.Biol., 19, 2012
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3VP7
 | | Crystal structure of the beta-alpha repeated, autophagy-specific (BARA) domain of Vps30/Atg6 | | Descriptor: | Vacuolar protein sorting-associated protein 30 | | Authors: | Noda, N.N, Kobayashi, T, Adachi, W, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2012-02-28 | | Release date: | 2012-03-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the novel C-terminal domain of vacuolar protein sorting 30/autophagy-related protein 6 and its specific role in autophagy.
J.Biol.Chem., 287, 2012
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3W1S
 | | Crystal structure of Saccharomyces cerevisiae Atg12-Atg5 conjugate bound to the N-terminal domain of Atg16 | | Descriptor: | Autophagy protein 16, Autophagy protein 5, Ubiquitin-like protein ATG12 | | Authors: | Noda, N.N, Fujioka, Y, Hanada, T, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2012-11-20 | | Release date: | 2012-12-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation
Embo Rep., 14, 2013
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7W36
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2DYT
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