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5Z7L
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BU of 5z7l by Molmil
Crystal structure of NDP52 SKICH region in complex with NAP1
Descriptor: 5-azacytidine-induced protein 2, Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL
Authors:Fu, T, Pan, L.F.
Deposit date:2018-01-29
Release date:2019-01-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7EA7
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BU of 7ea7 by Molmil
crystal structure of NAP1 LIR in complex with GABARAP
Descriptor: Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif
Authors:Fu, T, Pan, L.
Deposit date:2021-03-06
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7EA2
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BU of 7ea2 by Molmil
crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain
Descriptor: 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ...
Authors:Fu, T, Pan, L.
Deposit date:2021-03-06
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7EAA
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BU of 7eaa by Molmil
crystal structure of NDP52 SKICH domain in complex with RB1CC1 coiled-coil domain
Descriptor: Calcium-binding and coiled-coil domain-containing protein 2, RB1-inducible coiled-coil protein 1
Authors:Fu, T, Pan, L.
Deposit date:2021-03-06
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
5Z7A
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BU of 5z7a by Molmil
Crystal structure of NDP52 SKICH region
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL, ...
Authors:Pan, L.F, Fu, T, Liu, J.P, Xie, X.Q.
Deposit date:2018-01-27
Release date:2019-01-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5Z7G
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BU of 5z7g by Molmil
Crystal structure of TAX1BP1 SKICH region in complex with NAP1
Descriptor: 5-azacytidine-induced protein 2, GLYCEROL, Tax1-binding protein 1
Authors:Pan, L.F, Fu, T, Liu, J.P, Xie, X.Q, Wang, Y.L, Hu, S.C.
Deposit date:2018-01-28
Release date:2019-01-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8GH8
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BU of 8gh8 by Molmil
RuvA Holliday junction DNA complex
Descriptor: DNA (34-MER), Holliday junction branch migration complex subunit RuvA
Authors:Rish, A.D, Fu, T.
Deposit date:2023-03-09
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:RuvA Holliday junction DNA complex
To Be Published
5GP7
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BU of 5gp7 by Molmil
Structural basis for the binding between Tankyrase-1 and USP25
Descriptor: GLYCEROL, Tankyrase-1, Ubiquitin carboxyl-terminal hydrolase 25
Authors:Liu, J, Xu, D, Fu, T, Pan, L.
Deposit date:2016-08-01
Release date:2017-07-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:USP25 regulates Wnt signaling by controlling the stability of tankyrases
Genes Dev., 31, 2017
5JQE
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BU of 5jqe by Molmil
Crystal structure of caspase8 tDED
Descriptor: Sugar ABC transporter substrate-binding protein,Caspase-8 chimera
Authors:Fu, T, Li, Y, Lu, A, Wu, H.
Deposit date:2016-05-04
Release date:2016-10-26
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (3.157 Å)
Cite:Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol. Cell, 64, 2016
5ZAT
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BU of 5zat by Molmil
Crystal structure of 5-carboxylcytosine containing decamer dsDNA
Descriptor: DNA (5'-D(*CP*CP*AP*GP*(CAC)P*GP*CP*TP*GP*G)-3')
Authors:Fu, T.R, Zhang, L.
Deposit date:2018-02-08
Release date:2019-02-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
5ZAS
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BU of 5zas by Molmil
Crystal structure of 5-formylcytosine containing decamer dsDNA
Descriptor: BICARBONATE ION, DNA (5'-D(*CP*CP*AP*GP*(5FC)P*GP*CP*TP*GP*G)-3')
Authors:Fu, T.R, Zhang, L.
Deposit date:2018-02-08
Release date:2019-02-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
6JV3
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BU of 6jv3 by Molmil
Crystal structure of 5-hydoxylmethylcytosine containing decamer dsDNA
Descriptor: DNA (5'-D(*CP*CP*AP*GP*(5HC)P*GP*CP*TP*GP*G)-3')
Authors:Zhang, L, Wang, Y.X.
Deposit date:2019-04-15
Release date:2019-07-31
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
6JV5
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BU of 6jv5 by Molmil
Crystal structure of 5-methylcytosine containing decamer dsDNA
Descriptor: DNA (5'-D(*CP*CP*AP*GP*(5CM)P*GP*CP*TP*GP*G)-3')
Authors:Zhang, L, Wang, Y.X.
Deposit date:2019-04-15
Release date:2019-07-31
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
2NA6
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BU of 2na6 by Molmil
Transmembrane domain of mouse Fas/CD95 death receptor
Descriptor: Tumor necrosis factor receptor superfamily member 6
Authors:Fu, Q, Chou, J.J, Wu, H, Fu, T, Membrane Protein Structures by Solution NMR (MPSbyNMR)
Deposit date:2015-12-21
Release date:2016-01-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.
Mol.Cell, 61, 2016
6XKK
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BU of 6xkk by Molmil
Cryo-EM structure of the NLRP1-CARD filament
Descriptor: NACHT, LRR and PYD domains-containing protein 1
Authors:Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H.
Deposit date:2020-06-26
Release date:2020-11-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Nat Commun, 12, 2021
6XKJ
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BU of 6xkj by Molmil
Cryo-EM structure of CARD8-CARD filament
Descriptor: Caspase recruitment domain-containing protein 8
Authors:Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H.
Deposit date:2020-06-26
Release date:2020-11-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Nat Commun, 12, 2021
6NHW
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BU of 6nhw by Molmil
Structure of the transmembrane domain of the Death Receptor 5 - Dimer of Trimer
Descriptor: Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J, Pan, L, Fu, Q, Zhao, L, Chen, W, Piai, A, Fu, T, Wu, H.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
7BV6
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BU of 7bv6 by Molmil
Crystal structure of the autophagic STX17/SNAP29/VAMP8 SNARE complex
Descriptor: Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8
Authors:Li, Y, Pan, L.F.
Deposit date:2020-04-09
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BV4
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BU of 7bv4 by Molmil
Crystal structure of STX17 LIR region in complex with GABARAP
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein, ...
Authors:Li, Y, Pan, L.F.
Deposit date:2020-04-09
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.
Proc.Natl.Acad.Sci.USA, 117, 2020
4ZJB
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BU of 4zjb by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) in complex with holo-ACP from Helicobacter pylori
Descriptor: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, ...
Authors:Zhang, L, Zhang, L, Shen, X, Jiang, H.
Deposit date:2015-04-29
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis.
Cell Res., 26, 2016
6NHY
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BU of 6nhy by Molmil
Structure of the transmembrane domain of the Death Receptor 5 mutant (G217Y) - Trimer Only
Descriptor: Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J, Pan, L, Zhao, L, Chen, W, Piai, A, Fu, T, Wu, H, Liu, Z.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
6J56
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BU of 6j56 by Molmil
Crystal structure of Myosin VI CBD in complex with Tom1 MBM
Descriptor: Peptide from Target of Myb protein 1, Unconventional myosin-VI
Authors:Hu, S, Pan, L.
Deposit date:2019-01-10
Release date:2019-08-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering.
Nat Commun, 10, 2019
4O7Q
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BU of 4o7q by Molmil
Crystal Structure of the F27G AIM2 Pyrin Domain Mutant and Similarities of its Self-association to DED/DED Interactions
Descriptor: Interferon-inducible protein AIM2
Authors:Lu, A, Kabaleeswaran, V, Wu, H.
Deposit date:2013-12-26
Release date:2014-02-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal Structure of the F27G AIM2 PYD Mutant and Similarities of Its Self-Association to DED/DED Interactions.
J.Mol.Biol., 426, 2014
6N1H
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BU of 6n1h by Molmil
Cryo-EM structure of ASC-CARD filament
Descriptor: Apoptosis-associated speck-like protein containing a CARD
Authors:Li, Y, Fu, T, Wu, H.
Deposit date:2018-11-08
Release date:2018-12-05
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N1I
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BU of 6n1i by Molmil
Cryo-EM structure of NLRC4-CARD filament
Descriptor: NLR family CARD domain-containing protein 4
Authors:Li, Y, Fu, T, Wu, H.
Deposit date:2018-11-08
Release date:2018-12-05
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

 

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