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3HVT
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BU of 3hvt by Molmil
STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER
Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66)
Authors:Steitz, T.A, Smerdon, S.J, Jaeger, J, Wang, J, Kohlstaedt, L.A, Chirino, A.J, Friedman, J.M, Rice, P.A.
Deposit date:1994-07-25
Release date:1994-10-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
Proc.Natl.Acad.Sci.Usa, 91, 1994
1KFD
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BU of 1kfd by Molmil
CRYSTAL STRUCTURES OF THE KLENOW FRAGMENT OF DNA POLYMERASE I COMPLEXED WITH DEOXYNUCLEOSIDE TRIPHOSPHATE AND PYROPHOSPHATE
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA POLYMERASE I KLENOW FRAGMENT
Authors:Beese, L.S, Friedman, J.M, Steitz, T.A.
Deposit date:1993-09-23
Release date:1994-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate.
Biochemistry, 32, 1993
1XYE
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BU of 1xye by Molmil
T-to-THigh Transitions in Human Hemoglobin: alpha Y42A deoxy low salt
Descriptor: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
Authors:Kavanaugh, J.S, Rogers, P.H, Arnone, A, Hui, H.L, Wierzba, A, DeYoung, A, Kwiatkowski, L.D, Noble, R.W, Juszczak, L.J, Peterson, E.S, Friedman, J.M.
Deposit date:2004-11-09
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Intersubunit interactions associated with tyr42alpha stabilize the quaternary-T tetramer but are not major quaternary constraints in deoxyhemoglobin
Biochemistry, 44, 2005
1XZ2
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BU of 1xz2 by Molmil
wild-type hemoglobin deoxy no-salt
Descriptor: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
Authors:Kavanaugh, J.S, Rogers, P.H, Arnone, A, Hui, H.L, Wierzba, A, DeYoung, A, Kwiatkowski, L.D, Noble, R.W, Juszczak, L.J, Peterson, E.S, Friedman, J.M.
Deposit date:2004-11-11
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Intersubunit interactions associated with tyr42alpha stabilize the quaternary-T tetramer but are not major quaternary constraints in deoxyhemoglobin
Biochemistry, 44, 2005
1XZ4
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BU of 1xz4 by Molmil
Intersubunit Interactions Associated with Tyr42alpha Stabilize the Quaternary-T Tetramer but are not Major Quaternary Constraints in Deoxyhemoglobin: alphaY42A deoxyhemoglobin no-salt
Descriptor: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
Authors:Kavanaugh, J.S, Rogers, P.H, Arnone, A, Hui, H.L, Wierzba, A, DeYoung, A, Kwiatkowski, L.D, Noble, R.W, Juszczak, L.J, Peterson, E.S, Friedman, J.M.
Deposit date:2004-11-11
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Intersubunit interactions associated with tyr42alpha stabilize the quaternary-T tetramer but are not major quaternary constraints in deoxyhemoglobin
Biochemistry, 44, 2005
1AX8
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BU of 1ax8 by Molmil
Human obesity protein, leptin
Descriptor: OBESITY PROTEIN
Authors:Zhang, F, Beals, J.M, Briggs, S.L, Clawson, D.K, Wery, J.-P, Schevitz, R.W.
Deposit date:1997-10-31
Release date:1998-11-25
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the obese protein leptin-E100.
Nature, 387, 1997
1G7V
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BU of 1g7v by Molmil
CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEXES WITH THE MECHANISM-BASED INHIBITOR
Descriptor: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, {[(2,2-DIHYDROXY-ETHYL)-(2,3,4,5-TETRAHYDROXY-6-PHOSPHONOOXY-HEXYL)-AMINO]-METHYL}-PHOSPHONIC ACID
Authors:Asojo, O.A, Friedman, J.M, Belakhov, V, Shoham, Y, Adir, N, Baasov, T.
Deposit date:2000-11-14
Release date:2001-05-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanism-based inhibitor.
Biochemistry, 40, 2001
1G7U
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BU of 1g7u by Molmil
CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEX WITH SUBSTRATE PHOSPHOENOL PYRUVATE
Descriptor: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, PHOSPHOENOLPYRUVATE
Authors:Asojo, O.A, Friedman, J.M, Belakhov, V, Shoham, Y, Adir, N, Baasov, T.
Deposit date:2000-11-14
Release date:2001-05-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanism-based inhibitor.
Biochemistry, 40, 2001
5HBI
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BU of 5hbi by Molmil
SCAPHARCA DIMERIC HEMOGLOBIN, MUTANT T72I, CO-LIGANDED FORM
Descriptor: CARBON MONOXIDE, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Royer Junior, W.E.
Deposit date:1998-06-24
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mutational destabilization of the critical interface water cluster in Scapharca dimeric hemoglobin: structural basis for altered allosteric activity.
J.Mol.Biol., 284, 1998
6HBI
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BU of 6hbi by Molmil
SCAPHARCA DIMERIC HEMOGLOBIN, MUTANT T72V, DEOXY FORM
Descriptor: HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Royer Junior, W.E.
Deposit date:1998-06-25
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mutational destabilization of the critical interface water cluster in Scapharca dimeric hemoglobin: structural basis for altered allosteric activity.
J.Mol.Biol., 284, 1998
7HBI
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BU of 7hbi by Molmil
SCAPHARCA DIMERIC HEMOGLOBIN, MUTANT T72V, CO-LIGANDED FORM
Descriptor: CARBON MONOXIDE, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Royer Junior, W.E.
Deposit date:1998-06-25
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mutational destabilization of the critical interface water cluster in Scapharca dimeric hemoglobin: structural basis for altered allosteric activity.
J.Mol.Biol., 284, 1998
4HBI
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BU of 4hbi by Molmil
SCAPHARCA DIMERIC HEMOGLOBIN, MUTANT T72I, DEOXY FORM
Descriptor: HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Royer Junior, W.E.
Deposit date:1998-06-24
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mutational destabilization of the critical interface water cluster in Scapharca dimeric hemoglobin: structural basis for altered allosteric activity.
J.Mol.Biol., 284, 1998
1TV6
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BU of 1tv6 by Molmil
HIV-1 Reverse Transcriptase Complexed with CP-94,707
Descriptor: 3-[4-(2-METHYL-IMIDAZO[4,5-C]PYRIDIN-1-YL)BENZYL]-3H-BENZOTHIAZOL-2-ONE, reverse transcriptase p51 subunit, reverse transcriptase p66 subunit
Authors:Pata, J.D, Stirtan, W.G, Goldstein, S.W, Steitz, T.A.
Deposit date:2004-06-28
Release date:2004-07-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant RTs resistant to other non-nucleoside inhibitors
Proc.Natl.Acad.Sci.USA, 101, 2004
1KLN
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BU of 1kln by Molmil
DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX
Descriptor: DNA (5'-D(*GP*CP*CP*GP*CP*GP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*CP*GP*CP*GP*GP*CP*GP*GP*C)-3'), PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), ...
Authors:Beese, L.S, Derbyshire, V, Steitz, T.A.
Deposit date:1994-05-24
Release date:1994-11-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of DNA polymerase I Klenow fragment bound to duplex DNA.
Science, 260, 1993

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