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1ZVI
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN
分子名称:Nitric-oxide synthase, brain, ZINC ION, ...
著者Matter, H., Kumar, H.S., Fedorov, R., Frey, A., Kotsonis, P., Hartmann, E., Frohlich, L.G., Reif, A., Pfleiderer, W., Scheurer, P., Ghosh, D.K., Schlichting, I., Schmidt, H.H.
登録日2005-06-02
公開日2005-08-02
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
1ZVL
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RAT NEURONAL NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN COMPLEXED WITH NATURAL SUBSTRATE L-ARG.
分子名称:Nitric-oxide synthase, brain, ZINC ION, ...
著者Matter, H., Kumar, H.S., Fedorov, R., Frey, A., Kotsonis, P., Hartmann, E., Frohlich, L.G., Reif, A., Pfleiderer, W., Scheurer, P., Ghosh, D.K., Schlichting, I., Schmidt, H.H.
登録日2005-06-02
公開日2005-08-02
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
4AKA
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IPSE ALPHA-1, AN IGE-BINDING CRYSTALLIN
分子名称:IL-4-INDUCING PROTEIN
著者Meyer, N.H., Mayerhofer, H., Tripsianes, K., Barths, D., Blindow, S., Bade, S., Madl, T., Frey, A., Haas, H., Mueller-Dieckmann, J., Sattler, M., Scharmm, G.
登録日2012-02-22
公開日2013-03-13
最終更新日2015-09-23
実験手法SOLUTION NMR
主引用文献A Crystallin Fold in the Interleukin-4-Inducing Principle of Schistosoma Mansoni Eggs (Ipse/Alpha-1) Mediates Ige Binding for Antigen-Independent Basophil Activation
J.Biol.Chem., 290, 2015
4BA9
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THE STRUCTURAL BASIS FOR THE COORDINATION OF Y-FAMILY TRANSLESION DNA POLYMERASES BY REV1
分子名称:DNA POLYMERASE KAPPA, DNA REPAIR PROTEIN REV1, MAGNESIUM ION, ...
著者Grummitt, C.G., Kilkenny, M.L., Frey, A., Roe, S.M., Oliver, A.W., Sale, J.E., Pearl, L.H.
登録日2012-09-12
公開日2013-09-25
最終更新日2017-03-15
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献The Structural Basis for the Coordination of Y- Family Translesion DNA Polymerases by Rev1
To be Published
4EL6
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CRYSTAL STRUCTURE OF IPSE/ALPHA-1 FROM SCHISTOSOMA MANSONI EGGS
分子名称:IL-4-inducing protein
著者Mayerhofer, H., Meyer, H., Tripsianes, K., Barths, D., Blindow, S., Bade, S., Madl, T., Frey, A., Haas, H., Sattler, M., Schramm, G., Mueller-Dieckmann, J.
登録日2012-04-10
公開日2013-04-10
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structure and functional analysis of IPSE/alpha-1, an IL-4-inducing factor secreted from Schistosoma mansoni eggs, reveals an IgE-binding crystallin fold
To be Published
2QCC
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CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE, APO FORM
分子名称:Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION, GLYCEROL
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCD
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CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO UMP
分子名称:Uridine 5'-monophosphate synthase (UMP synthase), URIDINE-5'-MONOPHOSPHATE
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCE
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CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO SULFATE, GLYCEROL, AND CHLORIDE
分子名称:Uridine 5'-monophosphate synthase (UMP synthase), SULFATE ION, CHLORIDE ION, ...
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCF
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CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN (ASP312ASN MUTANT) OF HUMAN UMP SYNTHASE BOUND TO 5-FLUORO-UMP
分子名称:Uridine 5'-monophosphate synthase (UMP synthase), 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCG
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CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO 5-BROMO-UMP
分子名称:Uridine 5'-monophosphate synthase (UMP synthase), 5-BROMO-URIDINE-5'-MONOPHOSPHATE
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCH
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CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE BOUND TO 5-IODO-UMP
分子名称:Uridine 5'-monophosphate synthase (UMP synthase), IODIDE ION, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ...
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCL
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CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN (ASP312ASN MUTANT) OF HUMAN UMP SYNTHASE BOUND TO OMP
分子名称:Uridine 5'-monophosphate synthase (UMP synthase), OROTIDINE-5'-MONOPHOSPHATE, GLYCEROL
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCM
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CRYSTAL STRUCTURE OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN (ASP312ASN MUTANT) OF HUMAN UMP SYNTHASE BOUND TO 6-HYDROXYMETHYL-UMP
分子名称:Uridine 5'-monophosphate synthase (UMP synthase), 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE)
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCN
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COVALENT COMPLEX OF THE OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE DOMAIN OF HUMAN UMP SYNTHASE WITH 6-IODO-UMP
分子名称:Uridine 5'-monophosphate synthase, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ...
著者Wittmann, J., Rudolph, M.
登録日2007-06-19
公開日2007-11-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
1DMJ
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 5,6-CYCLIC-TETRAHYDROPTERIDINE
分子名称:NITRIC OXIDE SYNTHASE, ACETATE ION, CACODYLATE ION, ...
著者Kotsonis, P., Frohlich, L.G., Raman, C.S., Li, H., Berg, M., Gerwig, R., Groehn, V., Kang, Y., Al-Masoudi, N., Taghavi-Moghadam, S., Mohr, D., Munch, U., Schnabel, J., Martasek, P., Masters, B.S., Strobel, H., Poulos, T., Matter, H., Pfleiderer, W., Schmidt, H.H.
登録日1999-12-14
公開日2000-12-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001