Author results

1AB7
  • Download 1ab7
  • View 1ab7
Molmil generated image of 1ab7
NMR 15N RELAXATION AND STRUCTURAL STUDIES REVEAL CONFORMATIONAL EXCHANGE IN BARSTAR C40/82A, 30 STRUCTURES
Descriptor:BARSTAR
Authors:Wong, K.B., Fersht, A.R., Freund, S.M.V.
Deposit date:1997-02-04
Release date:1997-09-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR 15N relaxation and structural studies reveal slow conformational exchange in barstar C40/82A.
J.Mol.Biol., 268, 1997
1BTA
  • Download 1bta
  • View 1bta
Molmil generated image of 1bta
THREE-DIMENSIONAL SOLUTION STRUCTURE AND 13C ASSIGNMENTS OF BARSTAR USING NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor:BARSTAR
Authors:Lubienski, M.J., Bycroft, M., Freund, S.M.V., Fersht, A.R.
Deposit date:1994-05-09
Release date:1994-07-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure and 13C assignments of barstar using nuclear magnetic resonance spectroscopy.
Biochemistry, 33, 1994
1BTB
  • Download 1btb
  • View 1btb
Molmil generated image of 1btb
THREE-DIMENSIONAL SOLUTION STRUCTURE AND 13C ASSIGNMENTS OF BARSTAR USING NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor:BARSTAR
Authors:Lubienski, M.J., Bycroft, M., Freund, S.M.V., Fersht, A.R.
Deposit date:1994-05-09
Release date:1994-07-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure and 13C assignments of barstar using nuclear magnetic resonance spectroscopy.
Biochemistry, 33, 1994
1GO0
  • Download 1go0
  • View 1go0
Molmil generated image of 1go0
NMR STRUCTURE OF RIBOSOMAL PROTEIN L30E FROM THERMOCOCCUS CELER
Descriptor:50S RIBOSOMAL PROTEIN L30E
Authors:Chan, S.-H., Bycroft, M., Freund, S.M.V., Wong, K.-B.
Deposit date:2001-10-15
Release date:2003-06-12
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Solution Structure and Thermal Stability of Ribosomal Protein L30E from Hyperthermophilic Archaeon Thermococcus Celer
Protein Sci., 12, 2003
1GO1
  • Download 1go1
  • View 1go1
Molmil generated image of 1go1
NMR STRUCTURE OF RIBOSOMAL PROTEIN L30E FROM THERMOCOCCUS CELER.
Descriptor:50S RIBOSOMAL PROTEIN L30E
Authors:Chan, S.-H., Bycroft, M., Freund, S.M.V., Wong, K.-B.
Deposit date:2001-10-15
Release date:2003-06-12
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Solution Structure and Thermal Stability of Ribosomal Protein L30E from Hyperthermophilic Archaeon Thermococcus Celer
Protein Sci., 12, 2003
1H1J
  • Download 1h1j
  • View 1h1j
Molmil generated image of 1h1j
THE SAP DOMAIN IS A DNA-BINDING DOMAIN CAPABLE OF BINDING S/MAR DNA
Descriptor:THO1 PROTEIN
Authors:Jacobsen, J.O.B., Freund, S.M.V., Bycroft, M.
Deposit date:2002-07-16
Release date:2002-08-08
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:The Sap Domain is a DNA-Binding Domain Capable of Binding S/Mar DNA
To be Published
1ZTR
  • Download 1ztr
  • View 1ztr
Molmil generated image of 1ztr
SOLUTION STRUCTURE OF ENGRAILED HOMEODOMAIN L16A MUTANT
Descriptor:Segmentation polarity homeobox protein engrailed
Authors:Religa, T.L., Markson, J.S., Mayor, U., Freund, S.M.V., Fersht, A.R.
Deposit date:2005-05-27
Release date:2005-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a protein denatured state and folding intermediate.
Nature, 437, 2005
2BIV
  • Download 2biv
  • View 2biv
Molmil generated image of 2biv
CRYSTAL STRUCTURE OF THE WILD-TYPE MBT DOMAINS OF HUMAN SCML2
Descriptor:SEX COMB ON MIDLEG-LIKE PROTEIN 2, IODIDE ION, SODIUM ION
Authors:Santiveri, C.M., Allen, M.D., Sait, F., Bycroft, M.
Deposit date:2005-01-26
Release date:2005-02-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Malignant Brain Tumor Repeats of Human Scml2 Bind to Peptides Containing Monomethylated Lysine.
J.Mol.Biol., 382, 2008
2L9N
  • Download 2l9n
  • View 2l9n
Molmil generated image of 2l9n
STRUCTURE OF THE HUMAN SHWACHMAN-BODIAN-DIAMOND SYNDROME (SBDS) PROTEIN
Descriptor:Ribosome maturation protein SBDS
Authors:Hilcenko, C., Freund, S.M.V., Warren, A.J.
Deposit date:2011-02-21
Release date:2011-05-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome.
Genes Dev., 25, 2011
2V0E
  • Download 2v0e
  • View 2v0e
Molmil generated image of 2v0e
BRK DOMAIN FROM HUMAN CHD7
Descriptor:CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
Authors:Allen, M.D., Religa, T.L., Freund, S.M.V., Bycroft, M.
Deposit date:2007-05-14
Release date:2007-05-22
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Solution Structure of the Brk Domains from Chd7
J.Mol.Biol., 371, 2007
2V0F
  • Download 2v0f
  • View 2v0f
Molmil generated image of 2v0f
BRK DOMAIN FROM HUMAN CHD7
Descriptor:CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
Authors:Allen, M.D., Religa, T.L., Freund, S.M.V., Bycroft, M.
Deposit date:2007-05-14
Release date:2007-05-22
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Solution Structure of the Brk Domains from Chd7
J.Mol.Biol., 371, 2007
2VYT
  • Download 2vyt
  • View 2vyt
Molmil generated image of 2vyt
THE MBT REPEATS OF HUMAN SCML2 BIND TO PEPTIDES CONTAINING MONO METHYLATED LYSINE.
Descriptor:SEX COMB ON MIDLEG-LIKE PROTEIN 2, N-METHYL-LYSINE, TRIETHYLENE GLYCOL
Authors:Santiveri, C.M., Lechtenberg, B.C., Allen, M.D., Sathyamurthy, A., Jaulent, A.M., Freund, S.M.V., Bycroft, M.
Deposit date:2008-07-28
Release date:2008-08-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Malignant Brain Tumor Repeats of Human Scml2 Bind to Peptides Containing Monomethylated Lysine.
J.Mol.Biol., 382, 2008
2WGX
  • Download 2wgx
  • View 2wgx
Molmil generated image of 2wgx
HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-Y236F-N239Y-T253I-N268D
Descriptor:CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C., Khoo, K.H., Fersht, A.R.
Deposit date:2009-04-27
Release date:2009-05-12
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Stabilising the DNA-Binding Domain of P53 by Rational Design of its Hydrophobic Core.
Protein Eng.Des.Sel., 22, 2009
2X35
  • Download 2x35
  • View 2x35
Molmil generated image of 2x35
MOLECULAR BASIS OF HISTONE H3K36ME3 RECOGNITION BY THE PWWP DOMAIN OF BRPF1.
Descriptor:PEREGRIN
Authors:Vezzoli, A., Bonadies, N., Allen, M.D., Freund, S.M.V., Santiveri, C.M., Kvinlaug, B., Huntly, B.J.P., Gottgens, B., Bycroft, M.
Deposit date:2010-01-21
Release date:2010-02-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2X4W
  • Download 2x4w
  • View 2x4w
Molmil generated image of 2x4w
MOLECULAR BASIS OF HISTONE H3K36ME3 RECOGNITION BY THE PWWP DOMAIN OF BRPF1.
Descriptor:PEREGRIN, HISTONE H3.2, FORMIC ACID
Authors:Vezzoli, A., Bonadies, N., Allen, M.D., Freund, S.M.V., Santiveri, C.M., Kvinlaug, B., Huntly, B.J.P., Gottgens, B., Bycroft, M.
Deposit date:2010-02-02
Release date:2010-04-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2X4X
  • Download 2x4x
  • View 2x4x
Molmil generated image of 2x4x
MOLECULAR BASIS OF HISTONE H3K36ME3 RECOGNITION BY THE PWWP DOMAIN OF BRPF1.
Descriptor:PEREGRIN, HISTONE H3.2, SULFATE ION
Authors:Vezzoli, A., Bonadies, N., Allen, M.D., Freund, S.M.V., Santiveri, C.M., Kvinlaug, B., Huntly, B.J.P., Gottgens, B., Bycroft, M.
Deposit date:2010-02-02
Release date:2010-04-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2X4Y
  • Download 2x4y
  • View 2x4y
Molmil generated image of 2x4y
MOLECULAR BASIS OF HISTONE H3K36ME3 RECOGNITION BY THE PWWP DOMAIN OF BRPF1.
Descriptor:PEREGRIN, HISTONE H3.2, SULFATE ION
Authors:Vezzoli, A., Bonadies, N., Allen, M.D., Freund, S.M.V., Santiveri, C.M., Kvinlaug, B., Huntly, B.J.P., Gottgens, B., Bycroft, M.
Deposit date:2010-02-02
Release date:2010-04-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2XEW
  • Download 2xew
  • View 2xew
Molmil generated image of 2xew
CRYSTAL STRUCTURE OF K11-LINKED DIUBIQUITIN
Descriptor:UBIQUITIN, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Bremm, A., Freund, S.M.V., Komander, D.
Deposit date:2010-05-18
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lys11-Linked Ubiquitin Chains Adopt Compact Conformations and are Preferentially Hydrolyzed by the Deubiquitinase Cezanne
Nat.Struct.Mol.Biol., 17, 2010
2Y9T
  • Download 2y9t
  • View 2y9t
Molmil generated image of 2y9t
STRUCTURAL BASIS OF P63A SAM DOMAIN MUTANTS INVOLVED IN AEC SYNDROME
Descriptor:TUMOR PROTEIN 63
Authors:Sathyamurthy, A., Freund, S.M.V., Johnson, C.M., Allen, M.D.
Deposit date:2011-02-16
Release date:2011-08-03
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
2Y9U
  • Download 2y9u
  • View 2y9u
Molmil generated image of 2y9u
STRUCTURAL BASIS OF P63A SAM DOMAIN MUTANTS INVOLVED IN AEC SYNDROME
Descriptor:TUMOR PROTEIN 63, SULFATE ION
Authors:Sathyamurthy, A., Freund, S.M.V., Johnson, C.M., Allen, M.D.
Deposit date:2011-02-16
Release date:2011-08-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
2YMT
  • Download 2ymt
  • View 2ymt
Molmil generated image of 2ymt
GAMMA 2 ADAPTIN EAR DOMAIN CRYSTAL STRUCTURE WITH PHAGE PEPTIDE GEEWGPWV
Descriptor:AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, PHAGE DISPLAY DERIVED GAMMA 2 ADAPTIN EAR DOMAIN BINDING PEPTIDE, 1,3-PROPANDIOL
Authors:Juergens, M.C., Voros, J., Rautureau, G., Shepherd, D., Pye, V.E., Muldoon, J., Johnson, C.M., Ashcroft, A., Freund, S.M.V., Ferguson, N.
Deposit date:2012-10-10
Release date:2013-07-10
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
3ZHF
  • Download 3zhf
  • View 3zhf
Molmil generated image of 3zhf
GAMMA 2 ADAPTIN EAR DOMAIN CRYSTAL STRUCTURE WITH PRES1 SITE1 PEPTIDE NPDWDFN
Descriptor:AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, LARGE ENVELOPE PROTEIN, DI(HYDROXYETHYL)ETHER, ...
Authors:Juergens, M.C., Voros, J., Rautureau, G., Shepherd, D., Pye, V.E., Muldoon, J., Johnson, C.M., Ashcroft, A., Freund, S.M.V., Ferguson, N.
Deposit date:2012-12-21
Release date:2013-07-10
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
3ZLZ
  • Download 3zlz
  • View 3zlz
Molmil generated image of 3zlz
LYS6-LINKED TRI-UBIQUITIN
Descriptor:UBIQUITIN, ZINC ION
Authors:Hospenthal, M.K., Freund, S.M.V., Komander, D.
Deposit date:2013-02-04
Release date:2013-04-10
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Assembly, Analysis and Architecture of Atypical Ubiquitin Chains
Nat.Struct.Mol.Biol., 20, 2013
4A2A
  • Download 4a2a
  • View 4a2a
Molmil generated image of 4a2a
THERMOTOGA MARITIMA FTSA:FTSZ(336-351)
Descriptor:CELL DIVISION PROTEIN FTSA, PUTATIVE, CELL DIVISION PROTEIN FTSZ, ...
Authors:Szwedziak, P., Lowe, J.
Deposit date:2011-09-23
Release date:2012-04-25
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ftsa Forms Actin-Like Protofilaments
Embo J., 31, 2012
4A2B
  • Download 4a2b
  • View 4a2b
Molmil generated image of 4a2b
THERMOTOGA MARITIMA FTSA WITH ATP GAMMA S
Descriptor:CELL DIVISION PROTEIN FTSA, PUTATIVE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Szwedziak, P., Lowe, J.
Deposit date:2011-09-23
Release date:2012-04-25
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ftsa Forms Actin-Like Protofilaments
Embo J., 31, 2012
<123>