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MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN
Descriptor:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, SENDAI VIRUS NUCLEOPROTEIN
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science, 257, 1992

2VAA

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Descriptor:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science, 257, 1992

1VAC

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND CHICKEN OVALBUMIN
Descriptor:	BETA-2 MICROGLOBULIN, CHICKEN OVALBUMIN, MHC CLASS I H-2KB HEAVY CHAIN
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. Proc.Natl.Acad.Sci.USA, 92, 1995

1VAD

MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
Descriptor:	BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, YEAST ALPHA-GLUCOSIDASE
Authors:	Fremont, D.H, Wilson, I.A.
Deposit date:	1994-11-01
Release date:	1996-06-20
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. Proc.Natl.Acad.Sci.USA, 92, 1995

3OQ3

Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor
Descriptor:	1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ...
Authors:	Fremont, D.H, Lee, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2010-09-02
Release date:	2011-05-18
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor To be Published

3M5R

Crystal Structure of Swine Flu Virus NS1 Effector Domain from H1N1 Influenza A/California/07/2009
Descriptor:	Nonstructural protein 1
Authors:	Fremont, D.H, Yu, Y.Y.L, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2010-03-13
Release date:	2010-04-07
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal Structure of Swine Flu Virus NS1 Effector Domain from H1N1 Influenza A/California/07/2009 To be Published

1EYH

CRYSTAL STRUCTURE OF THE EPSIN N-TERMINAL HOMOLOGY (ENTH) DOMAIN AT 1.56 ANGSTROM RESOLUTION
Descriptor:	EPSIN
Authors:	Fremont, D.H.
Deposit date:	2000-05-06
Release date:	2000-06-07
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.56 Å)
Cite:	CRYSTAL STRUCTURE OF THE EPSIN N-TERMINAL HOMOLOGY (ENTH) DOMAIN AT 1.56 ANGSTROM RESOLUTION To be Published

1IAK

HISTOCOMPATIBILITY ANTIGEN I-AK
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-AK
Authors:	Fremont, D.H, Unanue, E.R, Hendrickson, W.A.
Deposit date:	1997-11-18
Release date:	1998-04-15
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. Immunity, 8, 1998

1IEA

HISTOCOMPATIBILITY ANTIGEN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK
Authors:	Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J.
Deposit date:	1996-04-05
Release date:	1997-06-05
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structures of an MHC class II molecule with covalently bound single peptides. Science, 272, 1996

1IEB

HISTOCOMPATIBILITY ANTIGEN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK, SULFATE ION
Authors:	Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J.
Deposit date:	1996-04-05
Release date:	1997-06-05
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structures of an MHC class II molecule with covalently bound single peptides. Science, 272, 1996

1K8I

CRYSTAL STRUCTURE OF MOUSE H2-DM
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II H2-M alpha chain, MHC class II H2-M beta 2 chain
Authors:	Fremont, D.H, Crawford, F, Marrack, P, Hendrickson, W, Kappler, J.
Deposit date:	2001-10-24
Release date:	2001-12-05
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Crystal structure of mouse H2-M. Immunity, 9, 1998

1KT2

CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, ...
Authors:	Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J.
Deposit date:	2002-01-15
Release date:	2002-05-01
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002

1KTD

CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, glycine rich linker, ...
Authors:	Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J.
Deposit date:	2002-01-15
Release date:	2002-05-01
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002

6NK3

Crystal structure of murine Mxra8 ectodomain
Descriptor:	Matrix remodeling-associated protein 8
Authors:	Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-01-04
Release date:	2019-05-22
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor. Cell, 177, 2019

6ORT

Crystal Structure of Bos taurus Mxra8 Ectodomain
Descriptor:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Matrix remodeling-associated protein 8
Authors:	Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-04-30
Release date:	2020-03-04
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. Cell Host Microbe, 27, 2020

6E47

Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Glycochenodeoxycholic Acid
Descriptor:	1,2-ETHANEDIOL, CMRF35-like molecule 1, GLYCOCHENODEOXYCHOLIC ACID, ...
Authors:	Nelson, C.A, Fremont, D.H.
Deposit date:	2018-07-16
Release date:	2018-09-12
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6E48

Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid
Descriptor:	(3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:	Nelson, C.A, Fremont, D.H.
Deposit date:	2018-07-16
Release date:	2018-09-12
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.801 Å)
Cite:	Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

7SWX

SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-57 (three down conformation)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2021-11-21
Release date:	2022-11-23
Last modified:	2023-02-01
Method:	ELECTRON MICROSCOPY (3.13 Å)
Cite:	A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants To Be Published

7SWW

SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2021-11-21
Release date:	2022-11-23
Last modified:	2023-02-01
Method:	ELECTRON MICROSCOPY (3.13 Å)
Cite:	A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants To Be Published

5FFL

Crystal structure of mouse CD300lf at 1.6 Angstroms resolution.
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ...
Authors:	Nelson, C.A, Fremont, D.H.
Deposit date:	2015-12-18
Release date:	2016-08-31
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.602 Å)
Cite:	Discovery of a proteinaceous cellular receptor for a norovirus. Science, 353, 2016

8UFA

Eastern equine encephalitis virus (PE-6) VLP (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 protein, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2023-10-04
Release date:	2024-01-17
Last modified:	2024-01-31
Method:	ELECTRON MICROSCOPY (2.86 Å)
Cite:	Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus. Cell, 187, 2024

8UFC

Eastern equine encephalitis virus (PE-6) VLP in complex with VLDLR LA(1-2) (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2023-10-04
Release date:	2024-01-17
Last modified:	2024-01-31
Method:	ELECTRON MICROSCOPY (3.09 Å)
Cite:	Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus. Cell, 187, 2024

8UFB

Eastern equine encephalitis virus (PE-6) VLP in complex with full-length VLDLR (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2023-10-04
Release date:	2024-01-17
Last modified:	2024-01-31
Method:	ELECTRON MICROSCOPY (3.89 Å)
Cite:	Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus. Cell, 187, 2024

8SQN

CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ...
Authors:	Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2023-05-04
Release date:	2023-12-20
Method:	ELECTRON MICROSCOPY (3.89 Å)
Cite:	Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8. Cell, 186, 2023

6N08

Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:	Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2018-11-06
Release date:	2019-05-15
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.916 Å)
Cite:	Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2) to be published

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