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2AH2
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BU of 2ah2 by Molmil
Trypanosoma cruzi trans-sialidase in complex with 2,3-difluorosialic acid (covalent intermediate)
Descriptor: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CHLORIDE ION, GLYCEROL, ...
Authors:Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
Deposit date:2005-07-27
Release date:2005-08-23
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase
Structure, 12, 2004
1MS1
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BU of 1ms1 by Molmil
Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1S0I
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BU of 1s0i by Molmil
Trypanosoma cruzi trans-sialidase in complex with sialyl-lactose (Michaelis complex)
Descriptor: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, trans-sialidase
Authors:Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
Deposit date:2003-12-31
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase.
Structure, 12, 2004
1S0J
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BU of 1s0j by Molmil
Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex)
Descriptor: 4-METHYL-2-OXO-2H-CHROMEN-7-YL 5-(ACETYLAMINO)-3,5-DIDEOXY-L-ERYTHRO-NON-2-ULOPYRANOSIDONIC ACID, trans-sialidase
Authors:Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
Deposit date:2003-12-31
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase.
Structure, 12, 2004
1MR5
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BU of 1mr5 by Molmil
Orthorhombic form of Trypanosoma cruzi trans-sialidase
Descriptor: trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-18
Release date:2003-03-18
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS8
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BU of 1ms8 by Molmil
Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS5
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BU of 1ms5 by Molmil
Triclinic form of Trypanosoma cruzi trans-sialidase, soaked with N-acetylneuraminyl-a-2,3-thio-galactoside (NA-S-Gal)
Descriptor: trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS0
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BU of 1ms0 by Molmil
Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)and lactose
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS3
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BU of 1ms3 by Molmil
Monoclinic form of Trypanosoma cruzi trans-sialidase
Descriptor: trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS4
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BU of 1ms4 by Molmil
Triclinic form of Trypanosoma cruzi trans-sialidase
Descriptor: trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1MS9
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BU of 1ms9 by Molmil
Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with lactose
Descriptor: beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, trans-sialidase
Authors:Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M.
Deposit date:2002-09-19
Release date:2003-03-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The crystal structure and mode of action of trans-sialidase, a key enzyme of Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
1N1Y
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BU of 1n1y by Molmil
Trypanosoma rangeli sialidase in complex with sialic acid
Descriptor: N-acetyl-alpha-neuraminic acid, Sialidase
Authors:Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
Deposit date:2002-10-21
Release date:2003-01-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1T
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BU of 1n1t by Molmil
Trypanosoma rangeli sialidase in complex with DANA at 1.6 A
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SULFATE ION, Sialidase
Authors:Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
Deposit date:2002-10-20
Release date:2003-01-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1V
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BU of 1n1v by Molmil
Trypanosoma rangeli sialidase in complex with DANA
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SULFATE ION, Sialidase
Authors:Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
Deposit date:2002-10-21
Release date:2003-01-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1S
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BU of 1n1s by Molmil
Trypanosoma rangeli sialidase
Descriptor: SULFATE ION, Sialidase
Authors:Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
Deposit date:2002-10-20
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003

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