Author results

2M68
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NMR SOLUTION STRUCTURE ENSEMBLE OF 3-4D MUTANT DOMAIN 11 IGF2R IN COMPLEX WITH IGF2 (DOMAIN 11 STRUCTURE ONLY)
Descriptor:Insulin-like growth factor 2 receptor variant
Authors:Strickland, M., Williams, C., Richards, E., Minnall, L., Crump, M.P., Frago, S., Hughes, J., Garner, L., Hoppe, H., Rezgui, D., Zaccheo, O.J., Prince, S.N., Hassan, A.B., Whittaker, S.
Deposit date:2013-03-27
Release date:2014-10-15
Last modified:2016-06-01
Method:SOLUTION NMR
Cite:Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
2M6T
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NMR SOLUTION STRUCTURE ENSEMBLE OF 3-4D MUTANT DOMAIN 11 IGF2R
Descriptor:Insulin-like growth factor 2 receptor variant
Authors:Strickland, M., Williams, C., Richards, E., Minnall, L., Crump, M.P., Frago, S., Hughes, J., Garner, L., Hoppe, H., Rezgui, D., Zaccheo, O.J., Prince, S.N., Hassan, A.B., Whittaker, S.
Deposit date:2013-04-09
Release date:2014-10-15
Last modified:2016-06-01
Method:SOLUTION NMR
Cite:Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IEI
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X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A HIGH AFFINITY IGF2 ANTAGONIST (DOMAIN11 AB5 RHH) BASED ON HUMAN IGF2R DOMAIN 11
Descriptor:Cation-independent mannose-6-phosphate receptor, GLYCEROL, 1,2-ETHANEDIOL, ...
Authors:Nicholls, R.D., Williams, C., Strickland, M., Frago, S., Hassan, A.B., Crump, M.P.
Deposit date:2016-02-25
Release date:2016-05-18
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
2V5U
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I92A FLAVODOXIN FROM ANABAENA
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Martinez-Julvez, M., Herguedas, B., Frago, S., Serrano, A., Molina, R., Hamiaux, C., Schierbeek, B., Medina, M., Hermoso, J.A.
Deposit date:2007-07-10
Release date:2007-10-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Tuning of the Fmn Binding and Oxido-Reduction Properties by Neighboring Side Chains in Anabaena Flavodoxin.
Arch.Biochem.Biophys., 467, 2007
2BGI
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X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS COMPLEXED WITH THREE MOLECULES OF THE DETERGENT N-HEPTYL- BETA-D-THIOGLUCOSIDE AT 1.7 ANGSTROMS
Descriptor:FERREDOXIN-NADP(H) REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, HEPTYL 1-THIOHEXOPYRANOSIDE, ...
Authors:Perez-Dorado, J.I., Hermoso, J.A., Nogues, I., Frago, S., Bittel, C., Mayhew, S.G., Gomez-Moreno, C., Medina, M., Cortez, N., Carrillo, N.
Deposit date:2004-12-23
Release date:2005-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The Ferredoxin-Nadp(H) Reductase from Rhodobacter Capsulatus: Molecular Structure and Catalytic Mechanism
Biochemistry, 44, 2005
2BGJ
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X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS AT 2.1 ANGSTROMS
Descriptor:FERREDOXIN-NADP(H) REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Perez-Dorado, J.I., Hermoso, J.A., Nogues, I., Frago, S., Bittel, C., Mayhew, S.G., Gomez-Moreno, C., Medina, M., Cortez, N., Carrillo, N.
Deposit date:2004-12-23
Release date:2005-09-07
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The ferredoxin-NADP(H) reductase from Rhodobacter capsulatus: molecular structure and catalytic mechanism.
Biochemistry, 44, 2005
2L21
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CHICKEN IGF2R DOMAIN 11
Descriptor:Cation-independent mannose-6-phosphate receptor
Authors:Williams, C., Hoppe, H., Strickland, M., Frago, S., Ellis, R.Z., Wattana-Amorn, P., Prince, S.N., Zaccheo, O.J., Forbes, B., Jones, E.Y., Rezgui, D.Z., Crump, M.P., Hassan, A.B.
Deposit date:2010-08-10
Release date:2012-02-15
Method:SOLUTION NMR
Cite:CD loop dependency of the IGF2: M6P/IGF2 receptor binding interaction predates imprinting
To be Published
2L29
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COMPLEX STRUCTURE OF E4 MUTANT HUMAN IGF2R DOMAIN 11 BOUND TO IGF-II
Descriptor:Insulin-like growth factor 2 receptor variant, Insulin-like growth factor II
Authors:Williams, C., Hoppe, H., Rezgui, D., Strickland, M., Frago, S., Ellis, R.Z., Wattana-Amorn, P., Prince, S.N., Zaccheo, O.J., Forbes, B., Jones, E.Y., Crump, M.P., Hassan, A.B.
Deposit date:2010-08-13
Release date:2012-02-15
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
2L2A
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MUTATED DOMAIN 11 OF THE CYTOPLASMIC REGION OF THE CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
Descriptor:Insulin-like growth factor 2 receptor variant
Authors:Williams, C., Hoppe, H., Rezgui, D., Strickland, M., Frago, S., Ellis, R.Z., Wattana-Amorn, P., Prince, S.N., Zaccheo, O.J., Forbes, B., Jones, E.Y., Crump, M.P., Hassan, A.B.
Deposit date:2010-08-13
Release date:2012-02-15
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
2L2G
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SOLUTION STRUCTURE OF OPOSSUM DOMAIN 11
Descriptor:IGF2R DOMAIN 11
Authors:Williams, C., Hoppe, H., Rezgui, D., Rezgui, M., Frago, S., Ellis, R.Z., Wattana-Amorn, P., Prince, S.N., Zaccheo, O.J., Forbes, B., Jones, E.Y., Crump, M.P., Bassim, A.H.
Deposit date:2010-08-18
Release date:2012-02-15
Last modified:2015-02-25
Method:SOLUTION NMR
Cite:An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
2LLA
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NMR SOLUTION STRUCTURE ENSEMBLE OF DOMAIN 11 OF THE ECHIDNA M6P/IGF2R RECEPTOR
Descriptor:Mannose-6-phosphate/insulin-like growth factor II receptor
Authors:Strickland, M., Crump, M.P., Williams, C., Rezgui, D., Ellis, R.Z., Hoppe, H., Frago, S., Prince, S.N., Zaccheo, O.J., Forbes, B.E., Jones, E., Hassan, A.Z., Wattana-Amorn, P.
Deposit date:2011-11-05
Release date:2012-11-07
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
2X0K
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CRYSTAL STRUCTURE OF MODULAR FAD SYNTHETASE FROM CORYNEBACTERIUM AMMONIAGENES
Descriptor:RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION, PYROPHOSPHATE
Authors:Herguedas, B., Hermoso, J.A., Martinez-Julvez, M., Medina, M., Frago, S.
Deposit date:2009-12-15
Release date:2010-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Oligomeric State in the Crystal Structure of Modular Fad Synthetase Provides Insights Into its Sequential Catalysis in Prokaryotes
J.Mol.Biol., 400, 2010
2V5V
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W57E FLAVODOXIN FROM ANABAENA
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION
Authors:Herguedas, B., Martinez-Julvez, M., Perez-Dorado, I., Goni, G., Medina, M., Hermoso, J.A.
Deposit date:2007-07-10
Release date:2007-10-16
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Tuning of the Fmn Binding and Oxido-Reduction Properties by Neighboring Side Chains in Anabaena Flavodoxin.
Arch.Biochem.Biophys., 467, 2007
1GR1
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STRUCTURE OF FERREDOXIN-NADP+ REDUCTASE WITH GLU 139 REPLACED BY LYS (E139K)
Descriptor:FERREDOXIN--NADP+ REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Hermoso, J.A., Mayoral, T., Medina, M., Sanz-Aparicio, J., Gomez-Moreno, C.
Deposit date:2001-12-12
Release date:2002-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Probing the Role of Glutamic Acid 139 of Anabena Ferrodoxin-Nadp+ Reductase in the Interaction with Substrates
Eur.J.Biochem., 269, 2002
3ZUG
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E268D MUTANT OF FAD SYNTHETASE FROM CORYNEBACTERIUM AMMONIAGENES
Descriptor:RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION
Authors:Herguedas, B., Martinez-Julvez, M., Serrano, A., Medina, M.
Deposit date:2011-07-19
Release date:2012-08-01
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Key Residues at the Riboflavin Kinase Catalytic Site of the Bifunctional Riboflavin Kinase/Fmn Adenylyltransferase from Corynebacterium Ammoniagenes.
Cell Biochem.Biophys., 65, 2013
2VNH
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X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH NADP. FORM II AT 2.27 ANGSTROMS RESOLUTION
Descriptor:NADPH\:FERREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Perez-Dorado, I., Hermoso, J.A.
Deposit date:2008-02-05
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Coenzyme Binding and Hydride Transfer in Rhodobacter Capsulatus Ferredoxin/Flavodoxin Nadp(H) Oxidoreductase.
Biochim.Biophys.Acta, 1794, 2009
2VNI
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X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH 2P-AMP AT 2.37 ANGSTROMS RESOLUTION
Descriptor:NADPH\:FERREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, ADENOSINE-2'-5'-DIPHOSPHATE, ...
Authors:Perez-Dorado, I., Hermoso, J.A.
Deposit date:2008-02-05
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Coenzyme Binding and Hydride Transfer in Rhodobacter Capsulatus Ferredoxin/Flavodoxin Nadp(H) Oxidoreductase.
Biochim.Biophys.Acta, 1794, 2009
2VNJ
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X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH NADP. FORM I AT 2.13 ANGSTROMS RESOLUTION
Descriptor:NADPH\:FERREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Perez-Dorado, I., Hermoso, J.A.
Deposit date:2008-02-05
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Coenzyme Binding and Hydride Transfer in Rhodobacter Capsulatus Ferredoxin/Flavodoxin Nadp(H) Oxidoreductase.
Biochim.Biophys.Acta, 1794, 2009
2VNK
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X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH NADP. FORM III AT 1.93 ANGSTROMS RESOLUTION
Descriptor:NADPH\:FERREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Perez-Dorado, I., Hermoso, J.A.
Deposit date:2008-02-05
Release date:2008-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Coenzyme Binding and Hydride Transfer in Rhodobacter Capsulatus Ferredoxin/Flavodoxin Nadp(H) Oxidoreductase.
Biochim.Biophys.Acta, 1794, 2009
2WC1
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THREE-DIMENSIONAL STRUCTURE OF THE NITROGEN FIXATION FLAVODOXIN (NIFF) FROM RHODOBACTER CAPSULATUS AT 2.2 A
Descriptor:FLAVODOXIN, FLAVIN MONONUCLEOTIDE
Authors:Perez-Dorado, I., Bittel, C., Hermoso, J.A., Cortez, N., Carrillo, N.
Deposit date:2009-03-06
Release date:2010-04-21
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural and Phylogenetic Analysis of Rhodobacter Capsulatus Niff: Uncovering General Features of Nitrogen-Fixation (Nif)-Flavodoxins.
Int.J.Mol.Sci., 14, 2013
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