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1A1R
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BU of 1a1r by Molmil
HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX
Descriptor: NS3 PROTEIN, NS4A PROTEIN, ZINC ION
Authors:Kim, J.L, Morgenstern, K.A, Lin, C, Fox, T, Dwyer, M.D, Landro, J.A, Chambers, S.P, Markland, W, Lepre, C.A, O'Malley, E.T, Harbeson, S.L, Rice, C.M, Murcko, M.A, Caron, P.R, Thomson, J.A.
Deposit date:1997-12-15
Release date:1998-06-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide.
Cell(Cambridge,Mass.), 87, 1996
6EBM
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BU of 6ebm by Molmil
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha
Descriptor: Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera
Authors:Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBK
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BU of 6ebk by Molmil
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, Voltage-gated potassium channel subunit beta-2
Authors:Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBL
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BU of 6ebl by Molmil
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, cytosolic domain
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, Voltage-gated potassium channel subunit beta-2
Authors:Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
1CM8
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BU of 1cm8 by Molmil
PHOSPHORYLATED MAP KINASE P38-GAMMA
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PHOSPHORYLATED MAP KINASE P38-GAMMA
Authors:Bellon, S, Fitzgibbon, M.J, Fox, T, Hsiao, H.M, Wilson, K.P.
Deposit date:1999-05-17
Release date:2000-05-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation.
Structure Fold.Des., 7, 1999
6N7W
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BU of 6n7w by Molmil
Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)
Descriptor: DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N9V
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BU of 6n9v by Molmil
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1)
Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-12-04
Release date:2019-03-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N9U
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BU of 6n9u by Molmil
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)
Descriptor: DNA (44-MER), DNA primase/helicase, DNA-directed DNA polymerase, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-12-04
Release date:2019-03-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N9X
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BU of 6n9x by Molmil
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3)
Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-12-04
Release date:2019-03-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N7V
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BU of 6n7v by Molmil
Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes)
Descriptor: DNA (93-MER), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6B46
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BU of 6b46 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF1
Descriptor: Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B44
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BU of 6b44 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA
Descriptor: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B45
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BU of 6b45 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex
Descriptor: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B47
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BU of 6b47 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF2
Descriptor: Anti-CRISPR protein AcrF2, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B48
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BU of 6b48 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF10
Descriptor: Anti-CRISPR protein AcrF10, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
2AHT
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BU of 2aht by Molmil
Solution structure of domain 6 from the ai5(gamma)group II intron
Descriptor: 27-MER
Authors:Erat, M.C, Zerbe, O, Fox, T, Sigel, R.K.O.
Deposit date:2005-07-28
Release date:2006-10-17
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Solution structure of domain 6 from a self-splicing group II intron ribozyme: a Mg(2+) binding site is located close to the stacked branch adenosine.
Chembiochem, 8, 2007
2L62
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BU of 2l62 by Molmil
Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1. The second part of the puzzle.
Descriptor: EC protein I/II, ZINC ION
Authors:Loebus, J, Peroza, E.A, Bluethgen, N, Fox, T, Meyer-Klaucke, W, Zerbe, O, Freisinger, E.
Deposit date:2010-11-12
Release date:2011-05-25
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Protein and metal cluster structure of the wheat metallothionein domain gamma-E(c)-1: the second part of the puzzle.
J.Biol.Inorg.Chem., 16, 2011
2L61
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BU of 2l61 by Molmil
Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1. The second part of the puzzle.
Descriptor: CADMIUM ION, EC protein I/II
Authors:Loebus, J, Peroza, E.A, Bluethgen, N, Fox, T, Meyer-Klaucke, W, Zerbe, O, Freisinger, E.
Deposit date:2010-11-12
Release date:2011-05-25
Last modified:2013-06-19
Method:SOLUTION NMR
Cite:Protein and metal cluster structure of the wheat metallothionein domain gamma-E(c)-1: the second part of the puzzle.
J.Biol.Inorg.Chem., 16, 2011
1PME
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BU of 1pme by Molmil
STRUCTURE OF PENTA MUTANT HUMAN ERK2 MAP KINASE COMPLEXED WITH A SPECIFIC INHIBITOR OF HUMAN P38 MAP KINASE
Descriptor: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, ERK2, SULFATE ION
Authors:Xie, X.
Deposit date:1998-06-08
Release date:1999-06-08
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase.
Protein Sci., 7, 1998
1BT7
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BU of 1bt7 by Molmil
THE SOLUTION NMR STRUCTURE OF THE N-TERMINAL PROTEASE DOMAIN OF THE HEPATITIS C VIRUS (HCV) NS3-PROTEIN, FROM BK STRAIN, 20 STRUCTURES
Descriptor: NS3 SERINE PROTEASE, ZINC ION
Authors:Barbato, G, Cicero, D.O, Nardi, M.C, Steinkuhler, C, Cortese, R, De Francesco, R, Bazzo, R.
Deposit date:1998-09-01
Release date:1999-06-22
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism.
J.Mol.Biol., 289, 1999
8U1L
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BU of 8u1l by Molmil
Cryo-EM structure of the RAF1-HSP90-CDC37 complex in the closed state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, Hsp90 co-chaperone Cdc37, ...
Authors:Finci, L.I, Simanshu, D.K.
Deposit date:2023-09-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
Commun Biol, 7, 2024
8U1N
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BU of 8u1n by Molmil
Cryo-EM structure of the cross-linked HSP90 dimer (NTD-MD) in the semi-open state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, MAGNESIUM ION
Authors:Finci, L.I, Simanshu, D.K.
Deposit date:2023-09-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
Commun Biol, 7, 2024
8U1M
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BU of 8u1m by Molmil
Cryo-EM structure of the HSP90 dimer (NTD-MD) in the semi-open state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, MAGNESIUM ION
Authors:Finci, L.I, Simanshu, D.K.
Deposit date:2023-09-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
Commun Biol, 7, 2024
6TYI
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BU of 6tyi by Molmil
ExbB-ExbD complex in MSP1E3D1 nanodisc
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Biopolymer transport protein ExbB, ...
Authors:Celia, H, Botos, I, Jiang, J, Buchanan, S.K.
Deposit date:2019-08-09
Release date:2019-10-16
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the bacterial Ton motor subcomplex ExbB-ExbD provides information on structure and stoichiometry.
Commun Biol, 2, 2019
6UKO
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BU of 6uko by Molmil
Structure analysis of full-length mouse bcs1 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
Authors:Xia, D, Esser, L.
Deposit date:2019-10-05
Release date:2020-02-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020

 

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