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6Q8F
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NTERMINAL DOMAIN OF HUMAN SMU1
Descriptor:WD40 repeat-containing protein SMU1, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION
Authors:Tengo, L., Le Corre, L., Fournier, G., Ashraf, U., Busca, P., Rameix-Welti, M.-A., Gravier-Pelletier, C., Ruigrok, R.W.H., Jacob, Y., Vidalain, P.-O., Pietrancosta, N., Naffakh, N., McCarthy, A.A., Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Q8I
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NTERMINAL DOMAIN OF HUMAN SMU1 IN COMPLEX WITH HUMAN REDMID
Descriptor:WD40 repeat-containing protein SMU1, Protein Red
Authors:Tengo, L., Le Corre, L., Fournier, G., Ashraf, U., Busca, P., Rameix-Welti, M.-A., Gravier-Pelletier, C., Ruigrok, R.W.H., Jacob, Y., Vidalain, P.-O., Pietrancosta, N., Naffakh, N., McCarthy, A.A., Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Q8J
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NTERMINAL DOMAIN OF HUMAN SMU1 IN COMPLEX WITH LSP641
Descriptor:WD40 repeat-containing protein SMU1, 1-~{tert}-butyl-3-[6-(3,5-dimethoxyphenyl)-2-[[1-[1-(phenylmethyl)piperidin-4-yl]-1,2,3-triazol-4-yl]methylamino]pyrido[2,3-d]pyrimidin-7-yl]urea
Authors:Tengo, L., Le Corre, L., Fournier, G., Ashraf, U., Busca, P., Rameix-Welti, M.-A., Gravier-Pelletier, C., Ruigrok, R.W.H., Jacob, Y., Vidalain, P.-O., Pietrancosta, N., Naffakh, N., McCarthy, A.A., Crepin, T.
Deposit date:2018-12-14
Release date:2019-05-22
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
Proc.Natl.Acad.Sci.USA, 116, 2019
5M3H
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BAT INFLUENZA A/H17N10 POLYMERASE BOUND TO FOUR HEPTAD REPEATS OF SERINE 5 PHOSPHORYLATED POL II CTD
Descriptor:Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ...
Authors:Lukarska, M., Pflug, A., Cusack, S.
Deposit date:2016-10-14
Release date:2016-12-21
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541, 2017
5M3J
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INFLUENZA B POLYMERASE BOUND TO FOUR HEPTAD REPEATS OF SERINE 5 PHOSPHORYLATED POL II CTD
Descriptor:Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ...
Authors:Lukarska, M., Pflug, A., Cusack, S.
Deposit date:2016-10-14
Release date:2016-12-21
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541, 2017