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2QPF
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BU of 2qpf by Molmil
Crystal Structure of Mouse Transthyretin
Descriptor: Transthyretin
Authors:Reixach, N, Foss, T.R, Santelli, E, Pascual, J, Kelly, J.W, Buxbaum, J.N.
Deposit date:2007-07-23
Release date:2007-11-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Human-Murine Transthyretin Heterotetramers Are Kinetically Stable and Non-amyloidogenic: A LESSON IN THE GENERATION OF TRANSGENIC MODELS OF DISEASES INVOLVING OLIGOMERIC PROTEINS.
J.Biol.Chem., 283, 2008
1SMO
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BU of 1smo by Molmil
Crystal Structure of Human Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.47 .
Descriptor: L(+)-TARTARIC ACID, triggering receptor expressed on myeloid cells 1
Authors:Kelker, M.S, Foss, T.R, Peti, W, Teyton, L, Kelly, J.W, Wilson, I.A.
Deposit date:2004-03-09
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Crystal Structure of Human Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.47A.
J.Mol.Biol., 342, 2004
1QWH
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BU of 1qwh by Molmil
a covalent dimer of transthyretin that affects the amyloid pathway
Descriptor: Transthyretin
Authors:Foss, T, Kelker, M.S, Wilson, I.A.
Deposit date:2003-09-02
Release date:2004-09-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis.
J.Mol.Biol., 347, 2005
3TCT
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BU of 3tct by Molmil
Structure of wild-type TTR in complex with tafamidis
Descriptor: 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin
Authors:Connelly, S, Kelly, J.W, Wilson, I.A.
Deposit date:2011-08-09
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.
Proc.Natl.Acad.Sci.USA, 109, 2012

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