Author results

6R25
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STRUCTURE OF LSD2/NPAC-LINKER/NUCLEOSOME CORE PARTICLE COMPLEX: CLASS 3
Descriptor:Lysine-specific histone demethylase 1B, NPAC, Histone H3, ...
Authors:Marabelli, C., Pilotto, S., Chittori, S., Subramaniam, S., Mattevi, A.
Deposit date:2019-03-15
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (4.61 Å)
Cite:A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
6R1U
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STRUCTURE OF LSD2/NPAC-LINKER/NUCLEOSOME CORE PARTICLE COMPLEX: CLASS 2
Descriptor:Histone H3.2, Histone H4, Histone H2A, ...
Authors:Marabelli, C., Pilotto, S., Chittori, S., Subramaniam, S., Mattevi, A.
Deposit date:2019-03-15
Release date:2019-04-24
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (4.36 Å)
Cite:A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
6R1T
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STRUCTURE OF LSD2/NPAC-LINKER/NUCLEOSOME CORE PARTICLE COMPLEX: CLASS 1, FREE NUCLESOME
Descriptor:Histone H3, HISTONE H2A, Histone H2A, ...
Authors:Marabelli, C., Pilotto, S., Chittori, S., Subramaniam, S., Mattevi, A.
Deposit date:2019-03-15
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
6HHE
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CRYSTAL STRUCTURE OF THE MEDFLY ODORANT BINDING PROTEIN CCAPOBP22/CCAPOBP69A
Descriptor:Odorant binding protein OBP69a, SULFATE ION, 2-(2-METHOXYETHOXY)ETHANOL
Authors:Falchetto, M., Ciossani, G., Nenci, S., Mattevi, A., Gasperi, G., Forneris, F.
Deposit date:2018-08-28
Release date:2018-12-26
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (1.516 Å)
Cite:Structural and biochemical evaluation of Ceratitis capitata odorant-binding protein 22 affinity for odorants involved in intersex communication.
Insect Mol.Biol., 28, 2019
6H8M
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CRYSTAL STRUCTURE OF THE THIRD SRCR DOMAIN OF MURINE NEUROTRYPSIN.
Descriptor:Neurotrypsin
Authors:Canciani, A., Forneris, F.
Deposit date:2018-08-02
Release date:2019-02-20
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural characterization of the third scavenger receptor cysteine-rich domain of murine neurotrypsin.
Protein Sci., 28, 2019
6FXY
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH FE2+, MN2+, UDP-GAL - STRUCTURE FROM LONG-WAVELENGTH S-SAD
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.138 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXX
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH FE2+, MN2+, UDP-GAL, HG2+ SOAK
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, MERCURY (II) ION, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXT
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH FE2+, MN2+, UDP-GLC
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXR
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH FE2+, MN2+, UDP-GAL
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXM
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3 - COCRYSTAL WITH MN2+
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
6FXK
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN LYSYL HYDROXYLASE LH3
Descriptor:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Scietti, L., Chiapparino, A., De Giorgi, F., Fumagalli, M., Khoriauli, L., Nergadze, S., Basu, S., Olieric, V., Banushi, B., Giulotto, E., Gissen, P., Forneris, F.
Deposit date:2018-03-09
Release date:2018-08-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
Nat Commun, 9, 2018
5O35
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STRUCTURE OF COMPLEMENT PROTEINS COMPLEX
Descriptor:Complement C3, Complement factor H,Complement factor H, N-ACETYL-D-GLUCOSAMINE
Authors:Xue, X., Wu, J., Forneris, F., Gros, P.
Deposit date:2017-05-23
Release date:2017-06-28
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
5O32
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THE STRUCTURE OF COMPLEMENT COMPLEX
Descriptor:Complement C3, Complement factor H,Complement factor H, Complement factor I, ...
Authors:Xue, X., Wu, J., Forneris, F., Gros, P.
Deposit date:2017-05-23
Release date:2017-06-28
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (4.206209 Å)
Cite:Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
5LBQ
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LSD1-COREST1 IN COMPLEX WITH QUINAZOLINE-DERIVATIVE REVERSIBLE INHIBITOR
Descriptor:Lysine-specific histone demethylase 1A, REST corepressor 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Speranzini, V., Rotili, D., Ciossani, G., Pilotto, S., Forgione, M., Lucidi, A., Forneris, F., Velankar, S., Mai, A., Mattevi, A.
Deposit date:2016-06-16
Release date:2016-09-21
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Sci Adv, 2, 2016
5L3G
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LSD1-COREST1 IN COMPLEX WITH POLYMYXIN E (COLISTIN)
Descriptor:Lysine-specific histone demethylase 1A, REST corepressor 1, polymyxin E, ...
Authors:Speranzini, V., Rotili, D., Ciossani, G., Pilotto, S., Forgione, M., Lucidi, A., Forneris, F., Velankar, S., Mai, A., Mattevi, A.
Deposit date:2016-04-10
Release date:2016-09-21
Last modified:2016-10-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Sci Adv, 2, 2016
5L3F
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LSD1-COREST1 IN COMPLEX WITH POLYMYXIN B
Descriptor:Lysine-specific histone demethylase 1A, REST corepressor 1, Polmyxin B, ...
Authors:Speranzini, V., Rotili, D., Ciossani, G., Pilotto, S., Forgione, M., Lucidi, A., Forneris, F., Velankar, S., Mai, A., Mattevi, A.
Deposit date:2016-04-10
Release date:2016-09-21
Last modified:2016-10-05
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Sci Adv, 2, 2016
5L3E
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LSD1-COREST1 IN COMPLEX WITH QUINAZOLINE-DERIVATIVE REVERSIBLE INHIBITOR
Descriptor:Lysine-specific histone demethylase 1A, REST corepressor 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Speranzini, V., Rotili, D., Ciossani, G., Pilotto, S., Forgione, M., Lucidi, A., Forneris, F., Velankar, S., Mai, A., Mattevi, A.
Deposit date:2016-04-10
Release date:2016-09-21
Last modified:2016-10-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Sci Adv, 2, 2016
5FYD
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STRUCTURAL AND BIOCHEMICAL INSIGHTS INTO 7BETA-HYDROXYSTEROID DEHYDROGENASE STEREOSELECTIVITY
Descriptor:OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY PROTEIN, GLYCEROL
Authors:Savino, S., Ferrandi, E., Forneris, F., Rovida, S., Riva, S., Monti, D., Mattevi, A.
Deposit date:2016-03-07
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Biochemical Insights Into 7Beta-Hydroxysteroid Dehydrogenase Stereoselectivity.
Proteins, 84, 2016
5FUS
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CRYSTAL STRUCTURE OF B. CENOCEPACIA DFSA
Descriptor:PUTATIVE ENOYL COA HYDRATASE, SULFATE ION, GLYCEROL, ...
Authors:Spadaro, F., Scoffone, V.C., Chiarelli, L.R., Fumagalli, M., Buroni, S., Riccardi, G., Forneris, F.
Deposit date:2016-01-29
Release date:2016-06-01
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The Crystal Structure of Burkholderia Cenocepacia Dfsa Provides Insights Into Substrate Recognition and Quorum Sensing Fatty Acid Biosynthesis.
Biochemistry, 55, 2016
5FOB
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH SMALLPOX INHIBITOR OF COMPLEMENT (SPICE)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, SMALLPOX INHIBITOR OF COMPLEMENT SPICE, ...
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FOA
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH DAF (CCP2-4)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA CHAIN, DECAY ACCELERATING FACTOR, ...
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (4.188 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO9
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH CR1 (CCP15- 17)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT RECEPTOR TYPE 1, ...
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO8
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH MCP (CCP1-4)
Descriptor:COMPLEMENT C3, MEMBRANE COFACTOR PROTEIN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO7
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B AT 2.8 ANGSTROM RESOLUTION
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, N-ACETYL-D-GLUCOSAMINE
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5AJU
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CRYSTAL STRUCTURE OF LIGAND-FREE PHOSPHORIBOHYDROXYLASE LONELY GUY FROM CLAVICEPS PURPUREA IN COMPLEX WITH PHOSPHORIBOSE
Descriptor:PHOSPHORIBOHYDROLASE LONELY GUY, 5-O-phosphono-beta-D-ribofuranose, SULFATE ION
Authors:Dzurova, L., Savino, S., Forneris, F.
Deposit date:2015-02-27
Release date:2015-06-03
Last modified:2015-08-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Three-Dimensional Structure of "Lonely Guy" from Claviceps Purpurea Provides Insights Into the Phosphoribohydrolase Function of Rossmann Fold-Containing Lysine Decarboxylase-Like Proteins.
Proteins, 83, 2015
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