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2LPN
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BU of 2lpn by Molmil
Solution Structure of N-Terminal domain of human Conserved Dopamine Neurotrophic Factor (CDNF)
Descriptor: Cerebral dopamine neurotrophic factor
Authors:Latge, C, Cabral, K.M.S, Foguel, D, Pires, J.R.M, Almeida, M.S.
Deposit date:2012-02-15
Release date:2013-02-20
Last modified:2013-05-22
Method:SOLUTION NMR
Cite:(1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF).
Biomol.Nmr Assign., 7, 2013
3TFB
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BU of 3tfb by Molmil
Transthyretin natural mutant A25T
Descriptor: Transthyretin
Authors:Azevedo, E.P.C, Pereira, H.M, Garratt, R.C, Kelly, J.W, Foguel, D, Palhano, F.L.
Deposit date:2011-08-15
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.033 Å)
Cite:Dissecting the Structure, Thermodynamic Stability, and Aggregation Properties of the A25T Transthyretin (A25T-TTR) Variant Involved in Leptomeningeal Amyloidosis: Identifying Protein Partners That Co-Aggregate during A25T-TTR Fibrillogenesis in Cerebrospinal Fluid.
Biochemistry, 50, 2011
5DEJ
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BU of 5dej by Molmil
Transthyretin natural mutant A19D
Descriptor: CALCIUM ION, Transthyretin
Authors:Pereira, H.M, Ferreira, P, Andrade, C, Lima, C, Palhano, F, Foguel, D.
Deposit date:2015-08-25
Release date:2016-08-31
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Crystal structure of human Transthyretin natural mutant A19D
To Be Published
3CFQ
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BU of 3cfq by Molmil
Crystal structure of human wild-type transthyretin in complex with diclofenac
Descriptor: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Transthyretin
Authors:Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
Deposit date:2008-03-04
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
3CFN
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BU of 3cfn by Molmil
Crystal structure of human transthyretin in complex with 1-anilino-8-naphthalene sulfonate
Descriptor: 8-ANILINO-1-NAPHTHALENE SULFONATE, Transthyretin
Authors:Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
Deposit date:2008-03-04
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
3CFT
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BU of 3cft by Molmil
Crystal structure of human transthyretin in complex with 1-amino-5-naphthalene sulfonate
Descriptor: 5-aminonaphthalene-1-sulfonic acid, Transthyretin
Authors:Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
Deposit date:2008-03-04
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
3CFM
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BU of 3cfm by Molmil
Crystal structure of the apo form of human wild-type transthyretin
Descriptor: Transthyretin
Authors:Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
Deposit date:2008-03-04
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
3DGD
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BU of 3dgd by Molmil
Crystal structure of the F87M/L110M mutant of human transthyretin at pH 4.6
Descriptor: ACETATE ION, GLYCEROL, Transthyretin, ...
Authors:Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R.
Deposit date:2008-06-13
Release date:2008-07-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.383 Å)
Cite:Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition.
J.Biol.Chem., 285, 2010
3DID
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BU of 3did by Molmil
Crystal structure of the F87M/L110M mutant of human transthyretin at pH 4.6 soaked
Descriptor: ACETATE ION, GLYCEROL, Transthyretin, ...
Authors:Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R.
Deposit date:2008-06-20
Release date:2008-07-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition.
J.Biol.Chem., 285, 2010
4BIT
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BU of 4bit by Molmil
solution structure of cerebral dopamine neurotrophic factor (CDNF)
Descriptor: CEREBRAL DOPAMINE NEUROTROPHIC FACTOR
Authors:Latge, C, Cabral, K.M.S, Raymundo, D.P, Foguel, D, Herrmann, T, Almeida, M.S.
Deposit date:2013-04-13
Release date:2014-04-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Solution Structure and Dynamics of Full-Length Human Cerebral Dopamine Neurotrophic Factor and its Neuroprotective Role Against Alpha-Synuclein Oligomers.
J.Biol.Chem., 290, 2015
3OZK
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BU of 3ozk by Molmil
Crystal structure of human transthyretin variant A25T in complex with thyroxine (T4)
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, Transthyretin
Authors:Lima, L.M.T.R, Palmieri, L.C, Foguel, D, Palhano, F.L.
Deposit date:2010-09-25
Release date:2011-08-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human transthyretin variant A25T in complex with thyroxine (T4)
To be Published
3OZL
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BU of 3ozl by Molmil
Crystal structure of human transthyretin variant A25T in complex with flufenamic acid.
Descriptor: 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, Transthyretin
Authors:Lima, L.M.T.R, Palmieri, L.C, Foguel, D, Palhano, F.L.
Deposit date:2010-09-25
Release date:2011-09-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human transthyretin variant A25T in complex with flufenamic acid.
To be Published
3GPS
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BU of 3gps by Molmil
Crystal structure of the F87M/L110M mutant of human transthyretin at pH 5.5
Descriptor: ACETATE ION, GLYCEROL, Transthyretin, ...
Authors:Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R.
Deposit date:2009-03-23
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition.
J.Biol.Chem., 285, 2010
3GRG
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BU of 3grg by Molmil
Crystal structure of the F87M/L110M mutant of human transthyretin at pH 7.5
Descriptor: ACETATE ION, GLYCEROL, Transthyretin, ...
Authors:Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R.
Deposit date:2009-03-25
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition.
J.Biol.Chem., 285, 2010
3GRB
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BU of 3grb by Molmil
Crystal structure of the F87M/L110M mutant of human transthyretin at pH 6.5
Descriptor: ACETATE ION, GLYCEROL, Transthyretin, ...
Authors:Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R.
Deposit date:2009-03-25
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition.
J.Biol.Chem., 285, 2010
3I9I
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BU of 3i9i by Molmil
Crystal structure of human transthyretin variant A25T - #2
Descriptor: TRIETHYLENE GLYCOL, Transthyretin
Authors:Palmieri, L.C, Freire, J.B.B, Palhano, F.L, Azevedo, E.P.C, Foguel, D, Lima, L.M.T.R.
Deposit date:2009-07-11
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human transthyretin variant A25T - #2
To be Published
3I9P
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BU of 3i9p by Molmil
Crystal structure of human transthyretin - wild type
Descriptor: Transthyretin
Authors:Lima, L.M.T.R, Foguel, D.
Deposit date:2009-07-12
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human transthyretin - wild type
To be Published
3I9A
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BU of 3i9a by Molmil
Crystal structure of human transthyretin variant A25T - #1
Descriptor: TRIETHYLENE GLYCOL, Transthyretin
Authors:Palmieri, L.C, Freire, J.B.B, Palhano, F.L, Azevedo, E.P.C, Foguel, D, Lima, L.M.T.R.
Deposit date:2009-07-10
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of human transthyretin variant A25T - #1
To be Published
5LCN
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BU of 5lcn by Molmil
STRUCTURE OF THE PYROCOCCUS FURIOSUS ESTERASE PF2001 WITH SPACE GROUP P212121
Descriptor: PENTAETHYLENE GLYCOL, Uncharacterized protein
Authors:Varejao, N, Reverter, D.
Deposit date:2016-06-22
Release date:2017-08-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.
Structure, 26, 2018
5G5C
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BU of 5g5c by Molmil
Structure of the Pyrococcus furiosus Esterase Pf2001 with space group C2221
Descriptor: ESTERASE
Authors:Varejao, N, Reverter, D.
Deposit date:2016-05-23
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.
Structure, 26, 2018
5G59
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BU of 5g59 by Molmil
Structure of the Pyrococcus Furiosus Esterase Pf2001 with space group P3121
Descriptor: ESTERASE, MERCURY (II) ION
Authors:Varejao, N, Reverter, D.
Deposit date:2016-05-23
Release date:2017-06-21
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.613 Å)
Cite:Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.
Structure, 26, 2018
5G5M
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BU of 5g5m by Molmil
Structure of the Pyrococcus Furiosus Esterase Pf2001 with space group P21
Descriptor: ESTERASE, S-methyl hexanethioate
Authors:Varejao, N, Reverter, D.
Deposit date:2016-05-26
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.
Structure, 26, 2018
5FW6
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BU of 5fw6 by Molmil
Structure of human transthyretin mutant A108V
Descriptor: TRANSTHYRETIN
Authors:Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2017-03-08
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep, 7, 2017
5FO2
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BU of 5fo2 by Molmil
Structure of human transthyretin mutant A108I
Descriptor: TRANSTHYRETIN
Authors:Varejao, N, Santanna, R, Saraiva, M.J, Gallego, P, Ventura, S, Reverter, D.
Deposit date:2015-11-17
Release date:2016-11-30
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep, 7, 2017
3NEE
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BU of 3nee by Molmil
Wild type human transthyretin (TTR) complexed with GC-1 (TTRwt:GC-1)
Descriptor: GLYCEROL, Transthyretin, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
Authors:Trivella, D.B.B, Polikarpov, I.
Deposit date:2010-06-08
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011

 

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