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2F91
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1.2A RESOLUTION STRUCTURE OF A CRAYFISH TRYPSIN COMPLEXED WITH A PEPTIDE INHIBITOR, SGTI
Descriptor:hepatopancreas trypsin, Serine protease inhibitor I/II, CADMIUM ION, ...
Authors:Fodor, K., Harmat, V., Hetenyi, C., Kardos, J., Antal, J., Perczel, A., Patthy, A., Katona, G., Graf, L.
Deposit date:2005-12-05
Release date:2006-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis.
Biochemistry, 45, 2006
4KXK
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ALANINE-GLYOXYLATE AMINOTRANSFERASE VARIANT K390A/K391A IN COMPLEX WITH THE TPR DOMAIN OF HUMAN PEX5P
Descriptor:Serine--pyruvate aminotransferase, Peroxisomal targeting signal 1 receptor, SULFATE ION, ...
Authors:Fodor, K., Lou, Y., Wilmanns, M.
Deposit date:2013-05-27
Release date:2014-11-19
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-Induced Compaction of the PEX5 Receptor-Binding Cavity Impacts Protein Import Efficiency into Peroxisomes.
Traffic, 16, 2015
4KYO
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ALANINE-GLYOXYLATE AMINOTRANSFERASE VARIANT K390A IN COMPLEX WITH THE TPR DOMAIN OF HUMAN PEX5P
Descriptor:Serine-pyruvate aminotransferase, Peroxisomal targeting signal 1 receptor, SULFATE ION, ...
Authors:Fodor, K., Lou, Y., Wilmanns, M.
Deposit date:2013-05-29
Release date:2014-11-19
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ligand-Induced Compaction of the PEX5 Receptor-Binding Cavity Impacts Protein Import Efficiency into Peroxisomes.
Traffic, 16, 2015
3R9A
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HUMAN ALANINE-GLYOXYLATE AMINOTRANSFERASE IN COMPLEX WITH THE TPR DOMAIN OF HUMAN PEX5P
Descriptor:Serine--pyruvate aminotransferase, Peroxisomal targeting signal 1 receptor, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Fodor, K., Wilmanns, M.
Deposit date:2011-03-25
Release date:2011-05-11
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular requirements for peroxisomal targeting of alanine-glyoxylate aminotransferase as an essential determinant in primary hyperoxaluria type 1
Plos Biol., 10, 2012
4FR2
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ALCOHOL DEHYDROGENASE FROM OENOCOCCUS OENI
Descriptor:1,3-propanediol dehydrogenase, NICKEL (II) ION
Authors:Fodor, K., Skander, E., Wilmanns, M.
Deposit date:2012-06-26
Release date:2013-06-05
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and biochemical characterisation of a NAD(+)-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial biotechnology applications.
Appl.Microbiol.Biotechnol., 97, 2013
4I8A
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ALANINE-GLYOXYLATE AMINOTRANSFERASE VARIANT S187F
Descriptor:Serine-pyruvate aminotransferase, GLYCEROL
Authors:Fodor, K., Oppici, E., Williams, C., Cellini, B., Wilmanns, M.
Deposit date:2012-12-03
Release date:2013-05-01
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications.
Proteins, 81, 2013
2JET
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CRYSTAL STRUCTURE OF A TRYPSIN-LIKE MUTANT (S189D , A226G) CHYMOTRYPSIN.
Descriptor:CHYMOTRYPSINOGEN B CHAIN A, CHYMOTRYPSINOGEN B CHAIN B, CHYMOTRYPSINOGEN B CHAIN C
Authors:Jelinek, B., Katona, G., Fodor, K., Venekei, I., Graf, L.
Deposit date:2007-01-22
Release date:2007-09-18
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of a Trypsin-Like Mutant Chymotrypsin: The Role of Position 226 in the Activity and Specificity of S189D Chymotrypsin.
Protein J., 27, 2008
4DJZ
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CATALYTIC FRAGMENT OF MASP-1 IN COMPLEX WITH ITS SPECIFIC INHIBITOR DEVELOPED BY DIRECTED EVOLUTION ON SGCI SCAFFOLD
Descriptor:Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain, Protease inhibitor SGPI-2
Authors:Heja, D., Harmat, V., Fodor, K., Wilmanns, M., Dobo, J., Kekesi, K.A., Zavodszky, P., Gal, P., Pal, G.
Deposit date:2012-02-03
Release date:2012-04-25
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
J.Biol.Chem., 287, 2012
2WL8
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X-RAY CRYSTAL STRUCTURE OF PEX19P
Descriptor:PEROXISOMAL BIOGENESIS FACTOR 19
Authors:Schueller, N., Holton, S.J., Stanley, W.A., Song, Y.H., Konarev, P., Roessle, M., Erdmann, R., Schliebs, W., Wilmanns, M.
Deposit date:2009-06-22
Release date:2010-06-23
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Peroxisomal Receptor Pex19P Forms a Helical Mpts Recognition Domain.
Embo J., 29, 2010
3TVJ
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CATALYTIC FRAGMENT OF MASP-2 IN COMPLEX WITH ITS SPECIFIC INHIBITOR DEVELOPED BY DIRECTED EVOLUTION ON SGCI SCAFFOLD
Descriptor:Mannan-binding lectin serine protease 2 A chain, Mannan-binding lectin serine protease 2 B chain, Protease inhibitor SGPI-2, ...
Authors:Heja, D., Harmat, V., Dobo, J., Szasz, R., Kekesi, K.A., Zavodszky, P., Gal, P., Pal, G.
Deposit date:2011-09-20
Release date:2012-04-25
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
J.Biol.Chem., 287, 2012