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1TC1
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BU of 1tc1 by Molmil
A 1.4 ANGSTROM CRYSTAL STRUCTURE FOR THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE OF TRYPANOSOMA CRUZI
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FORMYCIN B, PROTEIN (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE)
Authors:Focia, P.J, Craig III, S.P, Nieves-Alicea, R, Fletterick, R.J, Eakin, A.E.
Deposit date:1998-09-30
Release date:1999-10-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi.
Biochemistry, 37, 1998
1TC2
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BU of 1tc2 by Molmil
TERNARY SUBSTRATE COMPLEX OF THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE FROM TRYPANOSOMA CRUZI
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, MAGNESIUM ION, ...
Authors:Focia, P.J, Craig III, S.P, Eakin, A.E.
Deposit date:1998-11-04
Release date:2000-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Approaching the transition state in the crystal structure of a phosphoribosyltransferase.
Biochemistry, 37, 1998
2CNW
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BU of 2cnw by Molmil
GDPALF4 complex of the SRP GTPases Ffh and FtsY
Descriptor: CELL DIVISION PROTEIN FTSY, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Focia, P.J, Gawronski-Salerno, J, Coon V, J.S, Freymann, D.M.
Deposit date:2006-05-24
Release date:2006-10-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of a Gdp:Alf(4) Complex of the Srp Gtpases Ffh and Ftsy, and Identification of a Peripheral Nucleotide Interaction Site.
J.Mol.Biol., 360, 2006
1OKK
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BU of 1okk by Molmil
HOMO-HETERODIMERIC COMPLEX OF THE SRP GTPASES
Descriptor: 1,2-ETHANEDIOL, CELL DIVISION PROTEIN FTSY, MAGNESIUM ION, ...
Authors:Focia, P.J, Freymann, D.M.
Deposit date:2003-07-26
Release date:2004-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Heterodimeric Gtpase Core of the Srp Targeting Complex
Science, 303, 2004
2IYL
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BU of 2iyl by Molmil
Structure of an FtsY:GDP complex
Descriptor: CELL DIVISION PROTEIN FTSY, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION
Authors:Focia, P.J, Freymann, D.M.
Deposit date:2006-07-18
Release date:2007-01-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structure of the T. aquaticus FtsY:GDP complex suggests functional roles for the C-terminal helix of the SRP GTPases.
Proteins, 66, 2007
4UUJ
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BU of 4uuj by Molmil
POTASSIUM CHANNEL KCSA-FAB WITH TETRAHEXYLAMMONIUM
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
Authors:Lenaeus, M.J, Burdette, D, Wagner, T, Focia, P.J, Gross, A.
Deposit date:2014-07-29
Release date:2014-08-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
6D71
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BU of 6d71 by Molmil
Crystal Structure of the Human Miro1 N-terminal GTPase bound to GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 1
Authors:Smith, K.P, Focia, P.J, Rice, S.E, Freymann, D.M.
Deposit date:2018-04-23
Release date:2019-10-09
Last modified:2022-10-05
Method:X-RAY DIFFRACTION (1.7180779 Å)
Cite:Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase.
J.Struct.Biol., 212, 2020
3IFX
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BU of 3ifx by Molmil
Crystal structure of the Spin-labeled KcsA mutant V48R1
Descriptor: POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, TETRABUTYLAMMONIUM ION, ...
Authors:Cieslak, J.A, Focia, P.J, Gross, A.
Deposit date:2009-07-26
Release date:2010-02-09
Last modified:2023-09-06
Method:EPR (3.56 Å), X-RAY DIFFRACTION
Cite:Electron Spin-Echo Envelope Modulation (ESEEM) Reveals Water and Phosphate Interactions with the KcsA Potassium Channel
Biochemistry, 49, 2010
2O26
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BU of 2o26 by Molmil
Structure of a class III RTK signaling assembly
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor, ...
Authors:Liu, H, Chen, X, Focia, P.J, He, X.
Deposit date:2006-11-29
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.
Embo J., 26, 2007
3EJJ
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BU of 3ejj by Molmil
Structure of M-CSF bound to the first three domains of FMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Colony stimulating factor-1, Macrophage colony-stimulating factor 1 receptor
Authors:Chen, X, Liu, H, Focia, P.J, Shim, A, He, X.
Deposit date:2008-09-18
Release date:2008-12-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.
Proc.Natl.Acad.Sci.USA, 105, 2008
2W0F
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BU of 2w0f by Molmil
Potassium Channel KcsA-Fab Complex with Tetraoctylammonium
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
Authors:Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A.
Deposit date:2008-08-14
Release date:2009-11-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
2BOC
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BU of 2boc by Molmil
Potassium channel KcsA-Fab complex in thallium with tetraethylarsonium (TEAs)
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
Authors:Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A.
Deposit date:2005-04-09
Release date:2005-04-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
2BOB
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BU of 2bob by Molmil
Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA)
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
Authors:Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A.
Deposit date:2005-04-09
Release date:2005-04-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
2JK5
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BU of 2jk5 by Molmil
Potassium Channel KcsA in complex with Tetrabutylammonium in high K
Descriptor: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ...
Authors:Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A.
Deposit date:2008-08-15
Release date:2009-11-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
1I0I
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BU of 1i0i by Molmil
ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-GLUTAMINE MUTANT
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ...
Authors:Canyuk, B, Focia, P.J, Eakin, A.E.
Deposit date:2001-01-29
Release date:2002-05-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
1I0L
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BU of 1i0l by Molmil
ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ASPARAGINE MUTANT
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ...
Authors:Canyuk, B, Focia, P.J, Eakin, A.E.
Deposit date:2001-01-29
Release date:2002-05-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
1I13
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BU of 1i13 by Molmil
ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ALANINE MUTANT
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, FORMIC ACID, ...
Authors:Canyuk, B, Focia, P.J, Eakin, A.E.
Deposit date:2001-01-30
Release date:2002-05-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
1I14
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BU of 1i14 by Molmil
ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-GLUTAMIC ACID MUTANT
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ...
Authors:Canyuk, B, Focia, P.J, Eakin, A.E.
Deposit date:2001-01-30
Release date:2002-05-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
5KUT
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BU of 5kut by Molmil
hMiro2 C-terminal GTPase domain, GDP-bound
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 2
Authors:Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M.
Deposit date:2016-07-13
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.693 Å)
Cite:Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
5KSY
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BU of 5ksy by Molmil
hMiro1 C-domain GDP Complex P41212 Crystal Form
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Mitochondrial Rho GTPase 1
Authors:Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M.
Deposit date:2016-07-10
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.482 Å)
Cite:Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
5KSZ
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BU of 5ksz by Molmil
hMiro EF hand and cGTPase domains in the GMPPCP-bound state
Descriptor: CHLORIDE ION, MAGNESIUM ION, Mitochondrial Rho GTPase 1, ...
Authors:Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M.
Deposit date:2016-07-10
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
5KTY
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BU of 5kty by Molmil
hMiro EF hand and cGTPase domains, GDP and Ca2+ bound state
Descriptor: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M.
Deposit date:2016-07-12
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.522 Å)
Cite:Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
5KSP
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BU of 5ksp by Molmil
hMiro1 C-domain GDP Complex C2221 Crystal Form
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Mitochondrial Rho GTPase 1
Authors:Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M.
Deposit date:2016-07-08
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.162 Å)
Cite:Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
5KSO
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BU of 5kso by Molmil
hMiro1 C-domain GDP-Pi Complex P3121 Crystal Form
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Mitochondrial Rho GTPase 1, PHOSPHATE ION
Authors:Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M.
Deposit date:2016-07-08
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
5KU1
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BU of 5ku1 by Molmil
hMiro1 EF hand and cGTPase domains in the GDP-bound state
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M.
Deposit date:2016-07-12
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016

 

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