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1YFN
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BU of 1yfn by Molmil
Versatile modes of peptide recognition by the AAA+ adaptor protein SspB- the crystal structure of a SspB-RseA complex
Descriptor: Sigma-E factor negative regulatory protein, Stringent starvation protein B
Authors:Levchenko, I, Grant, R.A, Flynn, J.M, Sauer, R.T, Baker, T.A.
Deposit date:2005-01-03
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Versatile modes of peptide recognition by the AAA+ adaptor protein SspB
Nat.Struct.Mol.Biol., 12, 2005
8E4W
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BU of 8e4w by Molmil
Crystal Structure of SARS CoV-2 Mpro mutant N142P with Pfizer Intravenous Inhibitor PF-00835231
Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
Authors:Shaqra, A.M, Schiffer, C.A.
Deposit date:2022-08-19
Release date:2024-02-07
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Contributions of Hyperactive Mutations in M pro from SARS-CoV-2 to Drug Resistance.
Acs Infect Dis., 10, 2024
8E5C
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BU of 8e5c by Molmil
Crystal Structure of SARS CoV-2 Mpro mutant L50F with Nirmatrelvir captured in two conformational states
Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5, CHLORIDE ION, ...
Authors:Shaqra, A.M, Schiffer, C.A.
Deposit date:2022-08-20
Release date:2024-02-07
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contributions of Hyperactive Mutations in M pro from SARS-CoV-2 to Drug Resistance.
Acs Infect Dis., 10, 2024
8DT9
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BU of 8dt9 by Molmil
Crystal Structure of SARS CoV-2 Mpro mutant L141R with Pfizer Intravenous Inhibitor PF-00835231
Descriptor: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, ...
Authors:Shaqra, A.M, Schiffer, C.A.
Deposit date:2022-07-25
Release date:2024-02-07
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Contributions of Hyperactive Mutations in M pro from SARS-CoV-2 to Drug Resistance.
Acs Infect Dis., 10, 2024

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