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7T6K
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BU of 7t6k by Molmil
Cryo-EM structure of TRPV5 at pH6 in nanodiscs
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6N
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BU of 7t6n by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 2
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6L
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BU of 7t6l by Molmil
Cryo-EM structure of TRPV5 at pH5 in nanodiscs
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6R
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BU of 7t6r by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs in the presence of Calmodulin
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6O
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BU of 7t6o by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 3
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6P
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BU of 7t6p by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6M
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BU of 7t6m by Molmil
Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1
Descriptor: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6J
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BU of 7t6j by Molmil
Cryo-EM structure of TRPV5 at pH8 in nanodiscs
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6Q
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BU of 7t6q by Molmil
Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs
Descriptor: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
8FFN
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BU of 8ffn by Molmil
RR-bound wildtype rabbit TRPV5 in nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ...
Authors:Fluck, E.C, De Jesus-Perez, J.J, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y.
Deposit date:2022-12-09
Release date:2024-02-07
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8TF4
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BU of 8tf4 by Molmil
Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and econazole
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, ERGOSTEROL, ...
Authors:De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
Deposit date:2023-07-07
Release date:2024-01-10
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural mechanism of TRPV5 inhibition by econazole.
Structure, 32, 2024
8TF2
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BU of 8tf2 by Molmil
Wildtype rabbit TRPV5 into nanodiscs in Apo state
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5
Authors:De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
Deposit date:2023-07-07
Release date:2024-01-10
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structural mechanism of TRPV5 inhibition by econazole.
Structure, 32, 2024
8TF3
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BU of 8tf3 by Molmil
Wildtype rabbit TRPV5 into nanodiscs in complex with econazole
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, ERGOSTEROL, ...
Authors:De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
Deposit date:2023-07-07
Release date:2024-01-10
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural mechanism of TRPV5 inhibition by econazole.
Structure, 32, 2024
8FFQ
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BU of 8ffq by Molmil
Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and ruthenium red
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ...
Authors:De Jesus-Perez, J.J, Fluck, E.C, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y.
Deposit date:2022-12-09
Release date:2024-02-07
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8FFM
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BU of 8ffm by Molmil
Wildtype rat TRPV2 in nanodiscs bound to RR and 2-APB
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2, ...
Authors:Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
Deposit date:2022-12-09
Release date:2024-02-07
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8FFL
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BU of 8ffl by Molmil
Wildtype rat TRPV2 in nanodiscs bound to RR
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2
Authors:Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
Deposit date:2022-12-09
Release date:2024-02-07
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
6PBF
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BU of 6pbf by Molmil
ZINC9155420-bound TRPV5 in nanodiscs
Descriptor: (1S)-1-(4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)ethyl [(2S)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetate, Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2019-06-13
Release date:2019-11-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure-based characterization of novel TRPV5 inhibitors.
Elife, 8, 2019
6PBE
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BU of 6pbe by Molmil
ZINC17988990-bound TRPV5 in nanodiscs
Descriptor: (4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methyl 3-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)propanoate, Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2019-06-13
Release date:2019-11-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structure-based characterization of novel TRPV5 inhibitors.
Elife, 8, 2019
7RK8
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BU of 7rk8 by Molmil
Cryo-EM Structure of Adeno-Associated Virus Serotype 9 with Engineered Peptide Domain PHP.B (AAV9-PHP.B)
Descriptor: Capsid protein VP1
Authors:Fluck, E.C, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2021-07-22
Release date:2021-08-04
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:Context-Specific Function of the Engineered Peptide Domain of PHP.B.
J.Virol., 95, 2021
7RK9
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BU of 7rk9 by Molmil
Cryo-EM Structure of Adeno-Associated Virus Serotype 1 with Engineered Peptide Domain PHP.B (AAV1-PHP.B)
Descriptor: Capsid protein
Authors:Fluck, E.C, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2021-07-22
Release date:2021-08-04
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (2.32 Å)
Cite:Context-Specific Function of the Engineered Peptide Domain of PHP.B.
J.Virol., 95, 2021
6DMR
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BU of 6dmr by Molmil
Lipid-bound full-length rbTRPV5
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2018-06-05
Release date:2018-10-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6DMU
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BU of 6dmu by Molmil
PI(4,5)P2 bound full-length rbTRPV5
Descriptor: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2018-06-05
Release date:2018-10-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6DMW
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BU of 6dmw by Molmil
Calmodulin-bound full-length rbTRPV5
Descriptor: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2018-06-05
Release date:2018-10-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018

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PDB entries from 2024-03-27

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