Author results

2VG9
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CRYSTAL STRUCTURE OF LOOP SWAP MUTANT OF NECALLIMASTIX PATRICIARUM XYN11A
Descriptor:BIFUNCTIONAL ENDO-1,4-BETA-XYLANASE A, CADMIUM ION, ACETATE ION
Authors:Vardakou, M., Dumon, C., Flint, J.E., Murray, J.W., Christakopoulos, P., Weiner, D.P., Juge, N., Lewis, R.J., Gilbert, H.J.
Deposit date:2007-11-09
Release date:2007-12-25
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Understanding the Structural Basis for Substrate and Inhibitor Recognition in Eukaryotic Gh11 Xylanases.
J.Mol.Biol., 375, 2008
2VGD
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CRYSTAL STRUCTURE OF ENVIRONMENTAL ISOLATED GH11 IN COMPLEX WITH XYLOBIOSE AND FERULOYL-ARABINO-XYLOTRIOSE
Descriptor:ENXYN11A, SODIUM ION, BETA-D-XYLOPYRANOSE, ...
Authors:Vardakou, M., Dumon, C., Flint, J.E., Murray, J.W., Christakopoulos, P., Weiner, D.P., Juge, N., Lewis, R.J., Gilbert, H.J.
Deposit date:2007-11-12
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Understanding the Structural Basis for Substrate and Inhibitor Recognition in Eukaryotic Gh11 Xylanases.
J.Mol.Biol., 375, 2008
2VPT
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CLOSTRIDIUM THERMOCELLUM FAMILY 3 CARBOHYDRATE ESTERASE
Descriptor:LIPOLYTIC ENZYME, CALCIUM ION
Authors:Correia, M.A.S., Prates, J.A.M., Bras, J., Fontes, C.M.G.A., Newman, J.A., Lewis, R.J., Gilbert, H.J., Flint, J.E.
Deposit date:2008-03-04
Release date:2008-05-06
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of a Cellulosomal Family 3 Carbohydrate Esterase from Clostridium Thermocellum Provides Insights Into the Mechanism of Substrate Recognition
J.Mol.Biol., 379, 2008
2VUJ
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ENVIRONMENTALLY ISOLATED GH11 XYLANASE
Descriptor:GH11 XYLANASE, GLYCEROL
Authors:Dumon, C., Varvak, A., Wall, M.A., Flint, J.E., Lewis, R.J., Lakey, J.H., Luginbuhl, P., Healey, S., Todaro, T., DeSantis, G., Sun, M., Parra-Gessert, L., Tan, X., Weiner, D.P., Gilbert, H.J.
Deposit date:2008-05-26
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
2VUL
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THERMOSTABLE MUTANT OF ENVIRONMENTALLY ISOLATED GH11 XYLANASE
Descriptor:GH11 XYLANASE, SULFATE ION, DODECAETHYLENE GLYCOL
Authors:Dumon, C., Varvak, A., Wall, M.A., Flint, J.E., Lewis, R.J., Lakey, J.H., Luginbuhl, P., Healey, S., Todaro, T., Desantis, G., Sun, M., Parra-Gessert, L., Tan, X., Weiner, D.P., Gilbert, H.J.
Deposit date:2008-05-27
Release date:2008-06-17
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
2W46
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CBM35 FROM CELLVIBRIO JAPONICUS ABF62
Descriptor:ESTERASE D, CALCIUM ION, SODIUM ION
Authors:Montainer, C., Lammerts van Bueren, A., Dumon, C., Flint, J.E., Correia, M.A., Prates, J.A., Firbank, S.J., Lewis, R.J., Grondin, G.G., Ghinet, M.G., Gloster, T.M., Herve, C., Knox, J.P., Talbot, B.G., Turkenburg, J.P., Kerovuo, J., Brzezinski, R., Fontes, C.M.G.A., Davies, G.J., Boraston, A.B., Gilbert, H.J.
Deposit date:2008-11-21
Release date:2009-01-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W47
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CLOSTRIDIUM THERMOCELLUM CBM35 IN COMPLEX WITH DELTA-4,5- ANHYDROGALACTURONIC ACID
Descriptor:LIPOLYTIC ENZYME, G-D-S-L, CALCIUM ION, ...
Authors:Montainer, C., Lammerts van Bueren, A., Dumon, C., Flint, J.E., Correia, M.A., Prates, J.A., Firbank, S.J., Lewis, R.J., Grondin, G.G., Ghinet, M.G., Gloster, T.M., Herve, C., Knox, J.P., Talbot, B.G., Turkenburg, J.P., Kerovuo, J., Brzezinski, R., Fontes, C.M.G.A., Davies, G.J., Boraston, A.B., Gilbert, H.J.
Deposit date:2008-11-21
Release date:2009-01-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W87
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XYL-CBM35 IN COMPLEX WITH GLUCURONIC ACID CONTAINING DISACCHARIDE.
Descriptor:ESTERASE D, CALCIUM ION, D-GLUCURONIC ACID, ...
Authors:Montainer, C., Bueren, A.L.v., Dumon, C., Flint, J.E., Correia, M.A., Prates, J.A., Firbank, S.J., Lewis, R.J., Grondin, G.G., Ghinet, M.G., Gloster, T.M., Herve, C., Knox, J.P., Talbot, B.G., Turkenburg, J.P., Kerovuo, J., Brzezinski, R., Fontes, C.M.G.A., Davies, G.J., Boraston, A.B., Gilbert, H.J.
Deposit date:2009-01-14
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W9X
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THE ACTIVE SITE OF A CARBOHYDRATE ESTERASE DISPLAYS DIVERGENT CATALYTIC AND NON-CATALYTIC BINDING FUNCTIONS
Descriptor:PUTATIVE ACETYL XYLAN ESTERASE, GLYCEROL
Authors:Montanier, C., Money, V.A., Pires, V., Flint, J.E., Benedita, P.A., Goyal, A., Prates, J.A., Izumi, A., Stalbrand, H., Morland, C., Cartmell, A., Kolenova, K., Topakas, E., Dobson, E., Bolam, D.N., Davies, G.J., Fontes, C.M., Gilbert, H.J.
Deposit date:2009-01-29
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.
Plos Biol., 7, 2009
2WAA
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STRUCTURE OF A FAMILY TWO CARBOHYDRATE ESTERASE FROM CELLVIBRIO JAPONICUS
Descriptor:XYLAN ESTERASE, PUTATIVE, AXE2C, ...
Authors:Montainer, C., Money, V.A., Pires, V.M.R., Flint, J.E., Pinheiro, B.A., Goyal, A., Prates, J.A.M., Izumi, A., Stalbrand, H., Kolenova, K., Topakas, E., Dodson, E.J., Bolam, D.N., Davies, G.J., Fontes, C.M.G.A., Gilbert, H.J.
Deposit date:2009-02-04
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.
Plos Biol., 7, 2009
2WAB
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STRUCTURE OF AN ACTIVE SITE MUTANT OF A FAMILY TWO CARBOHYDRATE ESTERASE FROM CLOSTRIDIUM THERMOCELLUM IN COMPLEX WITH CELLUOHEXASE
Descriptor:ENDOGLUCANASE E, BETA-D-GLUCOSE, GLYCEROL, ...
Authors:Montainer, C., Money, V.A., Pires, V.M.R., Flint, J.E., Pinheiro, B.A., Goyal, A., Prates, J.A.M., Izumi, A., Stalbrand, H., Kolenova, K., Topakas, E., Dodson, E.J., Bolam, D.N., Davies, G.J., Fontes, C.M.G.A., Gilbert, H.J.
Deposit date:2009-02-04
Release date:2009-03-24
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.
Plos Biol., 7, 2009
2WAO
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STRUCTURE OF A FAMILY TWO CARBOHYDRATE ESTERASE FROM CLOSTRIDIUM THERMOCELLUM IN COMPLEX WITH CELLOHEXAOSE
Descriptor:ENDOGLUCANASE E, BETA-D-GLUCOSE, FORMIC ACID
Authors:Montainer, C., Money, V.A., Pires, V.M.R., Flint, J.E., Pinheiro, B.A., Goyal, A., Prates, J.A.M., Izumi, A., Stalbrand, H., Kolenova, K., Topakas, E., Dodson, E.J., Bolam, D.N., Davies, G.J., Fontes, C.M.G.A., Gilbert, H.J.
Deposit date:2009-02-10
Release date:2009-10-06
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.
Plos Biol., 7, 2009
2WHJ
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UNDERSTANDING HOW DIVERSE MANNANASES RECOGNISE HETEROGENEOUS SUBSTRATES
Descriptor:BETA-MANNANASE, GLYCEROL, ACETATE ION, ...
Authors:Tailford, L.E., Ducros, V.M.A., Flint, J.E., Roberts, S.M., Morland, C., Zechel, D.L., Smith, N., Bjornvad, M.E., Borchert, T.V., Wilson, K.S., Davies, G.J., Gilbert, H.J.
Deposit date:2009-05-05
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2WHL
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UNDERSTANDING HOW DIVERSE MANNANASES RECOGNISE HETEROGENEOUS SUBSTRATES
Descriptor:BETA-MANNANASE, ACETATE ION, ALPHA-D-MANNOSE, ...
Authors:Tailford, L.E., Ducros, V.M.A., Flint, J.E., Roberts, S.M., Morland, C., Zechel, D.L., Smith, N., Bjornvad, M.E., Borchert, T.V., Wilson, K.S., Davies, G.J., Gilbert, H.J.
Deposit date:2009-05-05
Release date:2009-05-26
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2WHM
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CELLVIBRIO JAPONICUS MAN26A E121A AND E320G DOUBLE MUTANT IN COMPLEX WITH MANNOBIOSE
Descriptor:ENDO-1,4-BETA MANNANASE, MAN26A, ZINC ION, ...
Authors:Durcos, V.M.A., Davies, G.J., Flint, J.E., Gilbert, H.J.
Deposit date:2009-05-05
Release date:2009-05-26
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2XFD
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VCBM60 IN COMPLEX WITH CELLOBIOSE
Descriptor:CARBOHYDRATE BINDING MODULE, CALCIUM ION, CELLOBIOSE, ...
Authors:Montanier, C., Flint, J.E., Bolam, D.N., Xie, H., Liu, Z., Rogowski, A., Weiner, D.P., Nurizzo, D., Roberts, S.M., Turkenburg, J.P., Davies, G.J., Gilbert, H.J.
Deposit date:2010-05-21
Release date:2010-06-16
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules.
J.Biol.Chem., 285, 2010
2XFE
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VCBM60 IN COMPLEX WITH GALACTOBIOSE
Descriptor:CARBOHYDRATE BINDING MODULE, BETA-D-GALACTOSE, CALCIUM ION
Authors:Montanier, C., Flint, J.E., Bolam, D.N., Xie, H., Liu, Z., Rogowski, A., Weiner, D.P., Nurizzo, D., Roberts, S.M., Turkenburg, J.P., Davies, G.J., Gilbert, H.J.
Deposit date:2010-05-21
Release date:2010-06-16
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules.
J.Biol.Chem., 285, 2010
2XHH
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CIRCULAR PERMUTATION PROVIDES AN EVOLUTIONARY LINK BETWEEN TWO FAMILIES OF CALCIUM-DEPENDENT CARBOHYDRATE BINDING MODULES
Descriptor:CARBOHYDRATE BINDING MODULE, (2S)-2-hydroxybutanedioic acid, CALCIUM ION
Authors:Montanier, C., Flint, J.E., Bolam, D.N., Xie, H., Liu, Z., Rogowski, A., Weiner, D., Ratnaparkhe, S., Nurizzo, D., Roberts, S.M., Turkenburg, J.P., Davies, G.J., Gilbert, H.J.
Deposit date:2010-06-16
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules
J.Biol.Chem., 285, 2010
2XHJ
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CIRCULAR PERMUTATION PROVIDES AN EVOLUTIONARY LINK BETWEEN TWO FAMILIES OF CALCIUM-DEPENDENT CARBOHYDRATE BINDING MODULES. SEMET FORM OF VCBM60.
Descriptor:CALCIUM-DEPENDENT CARBOHYDRATE BINDING MODULE, CALCIUM ION
Authors:Montanier, C., Flint, J.E., Bolam, D.N., Xie, H., Liu, Z., Rogowski, A., Weiner, D., Ratnaparkhe, S., Nurizzo, D., Roberts, S.M., Turkenburg, J.P., Davies, G.J., Gilbert, H.J.
Deposit date:2010-06-16
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules
J.Biol.Chem., 285, 2010
2Y4J
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MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH LACTATE
Descriptor:MANNOSYLGLYCERATE SYNTHASE, LACTIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Nielsen, M.M., Suits, M.D.L., Yang, M., Barry, C.S., Martinez-Fleites, C., Tailford, L.E., Flint, J.E., Davis, B.G., Davies, G.J., Gilbert, H.J.
Deposit date:2011-01-07
Release date:2011-02-02
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase.
J.Biol.Chem., 286, 2011
2Y4K
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MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH MG-GDP
Descriptor:MANNOSYLGLYCERATE SYNTHASE, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Nielsen, M.M., Suits, M.D.L., Yang, M., Barry, C.S., Martinez-Fleites, C., Tailford, L.E., Flint, J.E., Davis, B.G., Davies, G.J., Gilbert, H.J.
Deposit date:2011-01-07
Release date:2011-02-02
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase.
J.Biol.Chem., 286, 2011
2Y4L
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MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH MANGANESE AND GDP
Descriptor:MANNOSYLGLYCERATE SYNTHASE, MANGANESE (II) ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Nielsen, M.M., Suits, M.D.L., Yang, M., Barry, C.S., Martinez-Fleites, C., Tailford, L.E., Flint, J.E., Davis, B.G., Davies, G.J., Gilbert, H.J.
Deposit date:2011-01-07
Release date:2011-02-02
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase.
J.Biol.Chem., 286, 2011
2Y4M
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MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH GDP-MANNOSE
Descriptor:MANNOSYLGLYCERATE SYNTHASE, MAGNESIUM ION, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), ...
Authors:Nielsen, M.M., Suits, M.D.L., Yang, M., Barry, C.S., Martinez-Fleites, C., Tailford, L.E., Flint, J.E., Davis, B.G., Davies, G.J., Gilbert, H.J.
Deposit date:2011-01-07
Release date:2011-02-02
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase.
J.Biol.Chem., 286, 2011
2YB7
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CBM62 IN COMPLEX WITH 6-ALPHA-D-GALACTOSYL-MANNOTRIOSE
Descriptor:CARBOHYDRATE BINDING FAMILY 6, GLYCEROL, CALCIUM ION, ...
Authors:Montanier, C.Y., Correia, M.A.S., Flint, J.E., Zhu, Y., McKee, L.S., Prates, J.A.M., Polizzi, S.J., Coutinho, P.M., Henrissat, B., Fontes, C.M.G.A., Gilbert, H.J.
Deposit date:2011-03-02
Release date:2011-08-17
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Novel, Noncatalytic Carbohydrate-Binding Module Displays Specificity for Galactose-Containing Polysaccharides Through Calcium-Mediated Oligomerization.
J.Biol.Chem., 286, 2011
2YFU
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CBM62 FROM CLOSTRIDIUM THERMOCELLUM XYL5A
Descriptor:CARBOHYDRATE BINDING FAMILY 6, CALCIUM ION, GLYCEROL
Authors:Montanier, C.Y., Correia, M.A.S., Flint, J.E., Zhu, Y., Basle, A., Mckee, L.S., Prates, J.A.M., Polizzi, S.J., Coutinho, P.M., Henrissat, B., Fontes, C.M.G.A., Gilbert, H.J.
Deposit date:2011-04-08
Release date:2011-05-18
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Novel, Noncatalytic Carbohydrate-Binding Module Displays Specificity for Galactose-Containing Polysaccharides Through Calcium-Mediated Oligomerization.
J.Biol.Chem., 286, 2011
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