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3F5C
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BU of 3f5c by Molmil
Structure of Dax-1:LRH-1 complex
Descriptor: Nuclear receptor subfamily 0 group B member 1, Nuclear receptor subfamily 5 group A member 2
Authors:Fletterick, R.J, Sablin, E.P.
Deposit date:2008-11-03
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1.
Proc.Natl.Acad.Sci.USA, 105, 2008
1ANE
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BU of 1ane by Molmil
ANIONIC TRYPSIN WILD TYPE
Descriptor: ANIONIC TRYPSIN, BENZAMIDINE
Authors:Fletterick, R.J, Mcgrath, M.E.
Deposit date:1994-12-21
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of an engineered, metal-actuated switch in trypsin.
Biochemistry, 32, 1993
1ANC
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BU of 1anc by Molmil
ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY LYS
Descriptor: ANIONIC TRYPSIN, BENZAMIDINE, CALCIUM ION
Authors:Fletterick, R.J, Mcgrath, M.E.
Deposit date:1994-12-21
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214.
Biochemistry, 31, 1992
1ANB
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BU of 1anb by Molmil
ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY GLU
Descriptor: ANIONIC TRYPSIN, BENZAMIDINE, CALCIUM ION
Authors:Fletterick, R.J, Mcgrath, M.E.
Deposit date:1994-12-21
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214.
Biochemistry, 31, 1992
1AND
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BU of 1and by Molmil
ANIONIC TRYPSIN MUTANT WITH ARG 96 REPLACED BY HIS
Descriptor: ANIONIC TRYPSIN, BENZAMIDINE, COPPER (II) ION
Authors:Fletterick, R.J, Mcgrath, M.E.
Deposit date:1994-12-21
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of an engineered, metal-actuated switch in trypsin.
Biochemistry, 32, 1993
1BF6
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BU of 1bf6 by Molmil
PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHOSPHOTRIESTERASE HOMOLOGY PROTEIN, ...
Authors:Buchbinder, J.L, Stephenson, R.C, Scanlan, T.S, Fletterick, R.J.
Deposit date:1998-05-27
Release date:1999-06-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family.
Biochemistry, 37, 1998
1BRA
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BU of 1bra by Molmil
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN
Descriptor: BENZAMIDINE, CALCIUM ION, TRYPSIN
Authors:Perona, J.J, Mcgrath, M.E, Fletterick, R.J.
Deposit date:1992-12-17
Release date:1994-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Relocating a negative charge in the binding pocket of trypsin.
J.Mol.Biol., 230, 1993
1BRC
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BU of 1brc by Molmil
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN
Descriptor: AMYLOID BETA-PROTEIN PRECURSOR INHIBITOR DOMAIN (APPI), TRYPSIN
Authors:Perona, J.J, Fletterick, R.J.
Deposit date:1992-12-17
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Relocating a negative charge in the binding pocket of trypsin.
J.Mol.Biol., 230, 1993
1BRB
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BU of 1brb by Molmil
CRYSTAL STRUCTURES OF RAT ANIONIC TRYPSIN COMPLEXED WITH THE PROTEIN INHIBITORS APPI AND BPTI
Descriptor: PANCREATIC TRYPSIN INHIBITOR, TRYPSIN
Authors:Perona, J.J, Fletterick, R.J.
Deposit date:1992-12-17
Release date:1994-07-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI.
J.Mol.Biol., 230, 1993
2AIM
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BU of 2aim by Molmil
CRUZAIN INHIBITED WITH BENZOYL-ARGININE-ALANINE-FLUOROMETHYLKETONE
Descriptor: BENZOYL-ARGININE-ALANINE-FLUORO-METHYL KETONE, CRUZAIN
Authors:Gillmor, S.A, Fletterick, R.J.
Deposit date:1997-04-21
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural determinants of specificity in the cysteine protease cruzain.
Protein Sci., 6, 1997
6DDA
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BU of 6dda by Molmil
Nurr1 Covalently Modified by a Dopamine Metabolite
Descriptor: 5-hydroxy-1,2-dihydro-6H-indol-6-one, BROMIDE ION, Nuclear receptor subfamily 4 group A member 2, ...
Authors:Bruning, J.M, Wang, Y, Otrabella, F, Boxue, T, Liu, H, Bhattacharya, P, Guo, S, Holton, J.M, Fletterick, R.J, Jacobson, M.P, England, P.M.
Deposit date:2018-05-09
Release date:2019-03-20
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite.
Cell Chem Biol, 26, 2019
3LVG
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BU of 3lvg by Molmil
Crystal structure of a clathrin heavy chain and clathrin light chain complex
Descriptor: Clathrin heavy chain 1, Clathrin light chain B
Authors:Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M.
Deposit date:2010-02-20
Release date:2010-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (7.94 Å)
Cite:Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
3LVH
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BU of 3lvh by Molmil
Crystal structure of a clathrin heavy chain and clathrin light chain complex
Descriptor: Clathrin heavy chain 1, Clathrin light chain B
Authors:Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M.
Deposit date:2010-02-20
Release date:2010-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (9 Å)
Cite:Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
1BG2
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BU of 1bg2 by Molmil
HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, KINESIN, ...
Authors:Kull, F.J, Sablin, E.P, Lau, R, Fletterick, R.J, Vale, R.D.
Deposit date:1998-06-04
Release date:1998-10-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the kinesin motor domain reveals a structural similarity to myosin.
Nature, 380, 1996
1BSX
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BU of 1bsx by Molmil
STRUCTURE AND SPECIFICITY OF NUCLEAR RECEPTOR-COACTIVATOR INTERACTIONS
Descriptor: 3,5,3'TRIIODOTHYRONINE, PROTEIN (GRIP1), PROTEIN (THYROID HORMONE RECEPTOR BETA)
Authors:Wagner, R.L, Darimont, B.D, Apriletti, J.W, Stallcup, M.R, Kushner, P.J, Baxter, J.D, Fletterick, R.J, Yamamoto, K.R.
Deposit date:1998-08-31
Release date:1999-08-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure and specificity of nuclear receptor-coactivator interactions.
Genes Dev., 12, 1998
3I00
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BU of 3i00 by Molmil
Crystal Structure of the huntingtin interacting protein 1 coiled coil domain
Descriptor: Huntingtin-interacting protein 1
Authors:Wilbur, J.D, Hwang, P.K, Brodsky, F.M, Fletterick, R.J.
Deposit date:2009-06-24
Release date:2010-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain.
Acta Crystallogr.,Sect.D, 66, 2010
2Z4J
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BU of 2z4j by Molmil
Crystal structure of AR LBD with SHP peptide NR Box 2
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor 0B2
Authors:Jouravel, N, Fletterick, R.J.
Deposit date:2007-06-19
Release date:2007-12-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interaction between the androgen receptor and a segment of its corepressor SHP
Acta Crystallogr.,Sect.D, 63, 2007
1A0Q
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BU of 1a0q by Molmil
29G11 COMPLEXED WITH PHENYL [1-(1-N-SUCCINYLAMINO)PENTYL] PHOSPHONATE
Descriptor: 29G11 FAB (HEAVY CHAIN), 29G11 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE, ...
Authors:Buchbinder, J.L, Stephenson, R.C, Scanlan, T.S, Fletterick, R.J.
Deposit date:1997-12-05
Release date:1999-03-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A comparison of the crystallographic structures of two catalytic antibodies with esterase activity.
J.Mol.Biol., 282, 1998
1AZZ
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BU of 1azz by Molmil
FIDDLER CRAB COLLAGENASE COMPLEXED TO ECOTIN
Descriptor: COLLAGENASE, ECOTIN
Authors:Perona, J.J, Fletterick, R.J.
Deposit date:1997-11-24
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an ecotin-collagenase complex suggests a model for recognition and cleavage of the collagen triple helix.
Biochemistry, 36, 1997
1YOK
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BU of 1yok by Molmil
crystal structure of human LRH-1 bound with TIF-2 peptide and phosphatidylglycerol
Descriptor: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2
Authors:Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, MacKay, J.A, Juzumiene, D, Bynum, J.M, Madauss, K, Montana, V, Lebedeva, L, Suzawa, M, Williams, J.D, Williams, S.P, Guy, R.K, Thornton, J.W, Fletterick, R.J, Willson, T.M, Ingraham, H.A.
Deposit date:2005-01-27
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.
Cell(Cambridge,Mass.), 120, 2005
1YTZ
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BU of 1ytz by Molmil
Crystal structure of skeletal muscle troponin in the Ca2+-activated state
Descriptor: ALPHA-[4-(1,1,3,3 - TETRAMETHYLBUTYL)PHENYL]-OMEGA-HYDROXY-POLY(OXY-1,2-ETHANEDIYL), CALCIUM ION, Troponin C, ...
Authors:Vinogradova, M.V, Stone, D.B, Malanina, G.G, Karatzaferi, C, Cooke, R, Mendelson, R.A, Fletterick, R.J.
Deposit date:2005-02-11
Release date:2005-04-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ca2+-regulated structural changes in troponin
Proc.Natl.Acad.Sci.Usa, 102, 2005
1YV0
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BU of 1yv0 by Molmil
Crystal structure of skeletal muscle troponin in the Ca2+-free state
Descriptor: MAGNESIUM ION, Troponin C, skeletal muscle, ...
Authors:Vinogradova, M.V, Stone, D.B, Malanina, G.G, Karatzaferi, C, Cooke, R, Mendelson, R.A, Fletterick, R.J.
Deposit date:2005-02-14
Release date:2005-04-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (7 Å)
Cite:Ca2+-regulated structural changes in troponin
Proc.Natl.Acad.Sci.USA, 102, 2005
1YGP
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BU of 1ygp by Molmil
PHOSPHORYLATED FORM OF YEAST GLYCOGEN PHOSPHORYLASE WITH PHOSPHATE BOUND IN THE ACTIVE SITE.
Descriptor: PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, YEAST GLYCOGEN PHOSPHORYLASE
Authors:Lin, K, Rath, V.L, Dai, S.C, Fletterick, R.J, Hwang, P.K.
Deposit date:1996-05-30
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A protein phosphorylation switch at the conserved allosteric site in GP.
Science, 273, 1996
3COB
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BU of 3cob by Molmil
Structural Dynamics of the Microtubule binding and regulatory elements in the Kinesin-like Calmodulin binding protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain-like protein, MAGNESIUM ION
Authors:Vinogradova, M.V, Malanina, G.G, Reddy, V, Reddy, A.S.N, Fletterick, R.J.
Deposit date:2008-03-27
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein.
J.Struct.Biol., 163, 2008
3CNZ
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BU of 3cnz by Molmil
Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain-like protein, MAGNESIUM ION
Authors:Vinogradova, M.V, Malanina, G.G, Reddy, V, Reddy, A.S.N, Fletterick, R.J.
Deposit date:2008-03-26
Release date:2008-06-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein.
J.Struct.Biol., 163, 2008

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