Author results

5OOU
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DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) YTRL-1 SELECTED BY DIRECTED EVOLUTION AGAINST LYSOZYME
分子名称:DARPin YTRL-1
著者Fischer, G., Hogan, B.J., Houlihan, G., Edmond, S., Huovinen, T.T.K., Hollfelder, F., Hyvonen, M.
登録日2017-08-08
公開日2018-08-29
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Designed Ankyrin Repeat Protein (DARPin) YTRL-1 selected by directed evolution against Lysozyme
To be published
5OP1
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DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) A4 IN COMPLEX WITH LYSOZYME
分子名称:DARPin A4, Lysozyme C, CHLORIDE ION
著者Fischer, G., Hogan, B.J., Houlihan, G., Edmond, S., Huovinen, T.T.K., Hollfelder, F., Hyvonen, M.
登録日2017-08-09
公開日2018-08-29
実験手法X-RAY DIFFRACTION (2.284 Å)
主引用文献Designed Ankyrin Repeat Protein (DARPin) A4 in complex with Lysozyme
To be published
5OP3
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DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) NDNH-1 SELECTED BY DIRECTED EVOLUTION AGAINST LYSOZYME
分子名称:DARPin NDNH-1, ACETATE ION, CALCIUM ION, ...
著者Fischer, G., Hogan, B.J., Houlihan, G., Edmond, S., Huovinen, T.T.K., Hollfelder, F., Hyvonen, M.
登録日2017-08-09
公開日2018-08-29
実験手法X-RAY DIFFRACTION (1.359 Å)
主引用文献Designed Ankyrin Repeat Protein (DARPin) NDNH-1 selected by directed evolution against Lysozyme
To be published
2W1P
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1.4 ANGSTROM CRYSTAL STRUCTURE OF P.PASTORIS AQUAPORIN, AQY1, IN A CLOSED CONFORMATION AT PH 8.0
分子名称:AQUAPORIN PIP2-7 7;, B-OCTYLGLUCOSIDE, CHLORIDE ION
著者Fischer, G., Kosinska-Eriksson, U., Aponte-Santamaria, C., Palmgren, M., Geijer, C., Hedfalk, K., Hohmann, S., de Groot, B.L., Neutze, R., Lindkvist-Petersson, K.
登録日2008-10-20
公開日2009-06-16
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism
Plos Biol., 7, 2009
2W2E
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1.15 ANGSTROM CRYSTAL STRUCTURE OF P.PASTORIS AQUAPORIN, AQY1, IN A CLOSED CONFORMATION AT PH 3.5
分子名称:AQUAPORIN PIP2-7 7, B-OCTYLGLUCOSIDE, CHLORIDE ION
著者Fischer, G., Kosinska-Eriksson, U., Aponte-Santamaria, C., Palmgren, M., Geijer, C., Hedfalk, K., Hohmann, S., de Groot, B.L., Neutze, R., Lindkvist-Petersson, K.
登録日2008-10-29
公開日2009-06-16
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism.1.15 A
Plos Biol., 7, 2009
5BN2
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ROOM TEMPERATURE STRUCTURE OF PICHIA PASTORIS AQUAPORIN AT 1.3 A
分子名称:AQY1 protein, B-OCTYLGLUCOSIDE, CHLORIDE ION, ...
著者Fischer, G., Kosinska Eriksson, U., Hedfalk, K., Neutze, R.
登録日2015-05-25
公開日2016-06-29
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Room Temperature Structure of Pichia pastoris aquaporin at 1.3 A
To Be Published
5JFG
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STRUCTURE OF HUMANISED RADA-MUTANT HUMRADA22F IN COMPLEX WITH PEPTIDE FHTA
分子名称:DNA repair and recombination protein RadA, PEPTIDE FHTA, DIMETHYL SULFOXIDE, ...
著者Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Venkitaraman, A., Abell, C., Blundell, T.L., Hyvonen, M.
登録日2016-04-19
公開日2016-10-26
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Humanisation of RadA from Pyrococcus furiosus
To Be Published
5OOS
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DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) YTRL-2 SELECTED BY DIRECTED EVOLUTION AGAINST LYSOZYME
分子名称:DARPin YTRL-2, CHLORIDE ION, NONAETHYLENE GLYCOL
著者Hogan, B.J., Fischer, G., Houlihan, G., Edmond, S., Huovinen, T.T.K., Hollfelder, F., Hyvonen, M.
登録日2017-08-08
公開日2018-08-29
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Designed Ankyrin Repeat Protein (DARPin) YTRL-2 selected by directed evolution against Lysozyme
To be published
5OOV
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DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) ETVD-1 IN COMPLEX WITH LYSOZYME
分子名称:DARPin ETVD-1, Lysozyme C
著者Houlihan, G., Fischer, G., Hogan, B.J., Edmond, S., Huovinen, T.T.K., Hollfelder, F., Hyvonen, M.
登録日2017-08-08
公開日2018-08-29
実験手法X-RAY DIFFRACTION (1.365 Å)
主引用文献Designed Ankyrin Repeat Protein (DARPin) ETVD-1 in complex with Lysozyme
To be published
4UPH
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CRYSTAL STRUCTURE OF PHOSPHONATE MONOESTER HYDROLASE OF AGROBACTERIUM RADIOBACTER
分子名称:SULFATASE (SULFURIC ESTER HYDROLASE) PROTEIN, MAGNESIUM ION, CHLORIDE ION
著者Fischer, G., Loo, B.v., Hyvonen, M., Hollfelder, F.
登録日2014-06-17
公開日2015-07-01
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily.
J. Am. Chem. Soc., 2018
5J4H
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STRUCTURE OF HUMANISED RADA-MUTANT HUMRADA22F IN COMPLEX WITH INDOLE-6-CARBOXYLIC ACID
分子名称:DNA repair and recombination protein RadA, 1H-indole-6-carboxylic acid, SODIUM ION, ...
著者Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Venkitaraman, A., Abell, C., Blundell, T.L., Hyvonen, M.
登録日2016-04-01
公開日2016-10-19
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (1.374 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5J4K
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STRUCTURE OF HUMANISED RADA-MUTANT HUMRADA22F IN COMPLEX WITH 1-INDANE-6-CARBOXYLIC ACID
分子名称:DNA repair and recombination protein RadA, SODIUM ION, CALCIUM ION, ...
著者Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Venkitaraman, A., Abell, C., Blundell, T.L., Hyvonen, M.
登録日2016-04-01
公開日2016-10-26
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (1.346 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5J4L
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APO-STRUCTURE OF HUMANISED RADA-MUTANT HUMRADA22F
分子名称:DNA repair and recombination protein RadA, CHLORIDE ION
著者Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Venkitaraman, A., Abell, C., Blundell, T.L., Hyvonen, M.
登録日2016-04-01
公開日2016-10-19
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5JEC
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APO-STRUCTURE OF HUMANISED RADA-MUTANT HUMRADA33F
分子名称:DNA repair and recombination protein RadA, CHLORIDE ION, SULFATE ION
著者Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Venkitaraman, A., Abell, C., Blundell, T.L., Hyvonen, M.
登録日2016-04-18
公開日2016-10-19
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5JED
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APO-STRUCTURE OF HUMANISED RADA-MUTANT HUMRADA28
分子名称:DNA repair and recombination protein RadA, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
著者Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Venkitaraman, A., Abell, C., Blundell, T.L., Hyvonen, M.
登録日2016-04-18
公開日2016-10-19
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (1.332 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5JEE
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APO-STRUCTURE OF HUMANISED RADA-MUTANT HUMRADA26F
分子名称:DNA repair and recombination protein RadA, CALCIUM ION
著者Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Venkitaraman, A., Abell, C., Blundell, T.L., Hyvonen, M.
登録日2016-04-18
公開日2016-10-19
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5KDD
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APO-STRUCTURE OF HUMANISED RADA-MUTANT HUMRADA22
分子名称:DNA repair and recombination protein RadA, SULFATE ION
著者Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Venkitaraman, A., Abell, C., Blundell, T.L., Hyvonen, M.
登録日2016-06-08
公開日2016-10-19
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
5NIR
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CRYSTAL STRUCTURE OF COLLAGEN 2A VWC DOMAIN
分子名称:Collagen alpha-1(II) chain, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
著者Fischer, G., Blythe, E., Hyvonen, M.
登録日2017-03-27
公開日2017-06-14
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2.
J. Biol. Chem., 292, 2017
1FD9
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CRYSTAL STRUCTURE OF THE MACROPHAGE INFECTIVITY POTENTIATOR PROTEIN (MIP) A MAJOR VIRULENCE FACTOR FROM LEGIONELLA PNEUMOPHILA
分子名称:PROTEIN (MACROPHAGE INFECTIVITY POTENTIATOR PROTEIN), ZINC ION
著者Riboldi-Tunnicliffe, A., Jessen, S., Konig, B., Rahfeld, J., Hacker, J., Fischer, G., Hilgenfeld, R.
登録日2000-07-20
公開日2001-07-25
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structure of Mip, a prolylisomerase from Legionella pneumophila
Nat.Struct.Biol., 8, 2001
3ZOJ
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HIGH-RESOLUTION STRUCTURE OF PICHIA PASTORIS AQUAPORIN AQY1 AT 0.88 A
分子名称:AQUAPORIN, B-OCTYLGLUCOSIDE, CHLORIDE ION
著者Kosinska-Eriksson, U., Fischer, G., Friemann, R., Enkavi, G., Tajkhorshid, E., Neutze, R.
登録日2013-02-21
公開日2013-06-26
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (0.88 Å)
主引用文献Subangstrom Resolution X-Ray Structure Details Aquaporin-Water Interactions
Science, 340, 2013
1EQ3
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NMR STRUCTURE OF HUMAN PARVULIN HPAR14
分子名称:PEPTIDYL-PROLYL CIS/TRANS ISOMERASE (PPIASE)
著者Sekerina, E., Rahfeld, U.J., Muller, J., Fischer, G., Bayer, P.
登録日2000-04-02
公開日2001-04-04
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the protein.
J.Mol.Biol., 301, 2000
1JNS
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NMR STRUCTURE OF THE E. COLI PEPTIDYL-PROLYL CIS/TRANS-ISOMERASE PARVULIN 10
分子名称:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C
著者Kuehlewein, A., Voll, G., Schelbert, B., Kessler, H., Fischer, G., Rahfeld, J.U., Gemmecker, G.
登録日2001-07-25
公開日2003-06-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of Escherichia coli Par10: The prototypic member of the Parvulin family of peptidyl-prolyl cis/trans isomerases.
Protein Sci., 13, 2004
1JNT
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NMR STRUCTURE OF THE E. COLI PEPTIDYL-PROLYL CIS/TRANS-ISOMERASE PARVULIN 10
分子名称:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C
著者Kuehlewein, A., Voll, G., Schelbert, B., Kessler, H., Fischer, G., Rahfeld, J.U., Gemmecker, G.
登録日2001-07-25
公開日2003-06-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of Escherichia coli Par10: The prototypic member of the Parvulin family of peptidyl-prolyl cis/trans isomerases.
Protein Sci., 13, 2004
3EY6
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CRYSTAL STRUCTURE OF THE FK506-BINDING DOMAIN OF HUMAN FKBP38
分子名称:FK506-binding protein 8
著者Parthier, C., Maestre-Martinez, M., Neumann, P., Edlich, F., Fischer, G., Luecke, C., Stubbs, M.T.
登録日2008-10-19
公開日2009-10-27
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding.
J.Mol.Recognit., 24, 2011
4JA7
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RAT PP5 CO-CRYSTALLIZED WITH P5SA-2
分子名称:Serine/threonine-protein phosphatase 5, MAGNESIUM ION
著者Haslbeck, V., Helmuth, M., Alte, F., Popowicz, G., Schmidt, W., Weiwad, M., Fischer, G., Gemmecker, G., Sattler, M., Striggow, F., Groll, M., Richter, K.
登録日2013-02-18
公開日2014-02-19
最終更新日2016-08-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
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