Author results

2NSQ
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF THE HUMAN E3 UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE PROTEIN
Descriptor:E3 ubiquitin-protein ligase NEDD4-like protein, 1,2-ETHANEDIOL, GLYCEROL
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-11-06
Release date:2006-12-19
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
To be Published
2F15
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GLYCOGEN-BINDING DOMAIN OF THE AMP-ACTIVATED PROTEIN KINASE BETA2 SUBUNIT
Descriptor:5'-AMP-activated protein kinase, beta-2 subunit
Authors:Walker, J.R., Wybenga-Groot, L., Finerty Jr., P.J., Newman, E., MacKenzie, F.M., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-11-14
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Glycogen-Binding Domain Of The Amp-Activated Protein Kinase beta2 Subunit
To be Published
2FAZ
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UBIQUITIN-LIKE DOMAIN OF HUMAN NUCLEAR ZINC FINGER PROTEIN NP95
Descriptor:Ubiquitin-like containing PHD and RING finger domains protein 1
Authors:Walker, J.R., Wybenga-Groot, L., Doherty, R.S., Finerty Jr., P.J., Newman, E., Mackenzie, F.M., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-12-08
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95
To be Published
2FZP
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CRYSTAL STRUCTURE OF THE USP8 INTERACTION DOMAIN OF HUMAN NRDP1
Descriptor:ring finger protein 41 isoform 1
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-02-10
Release date:2006-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2G7R
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X-RAY STRUCTURE OF THE DEATH DOMAIN OF THE HUMAN MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1
Descriptor:Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Authors:Walker, J.R., Wybenga-Groot, L., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-02-28
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1
To be Published
2GFO
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8
Descriptor:Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-03-22
Release date:2006-04-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2GWF
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STRUCTURE OF A USP8-NRDP1 COMPLEX
Descriptor:Ubiquitin carboxyl-terminal hydrolase 8, RING finger protein 41
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-05-04
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2I6T
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ORTHORHOMBIC STRUCTURE OF THE LDH DOMAIN OF HUMAN UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A
Descriptor:UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A, SULFATE ION, GLYCEROL
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Tempel, W., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S.
Deposit date:2006-08-29
Release date:2006-10-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Investigation into the L-lactate Dehydrogenase Domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
To be Published
2I7A
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DOMAIN IV OF HUMAN CALPAIN 13
Descriptor:Calpain 13, CALCIUM ION, SULFATE ION, ...
Authors:Walker, J.R., Ng, K., Davis, T.L., Ravulapalli, R., Butler-cole, C., Finerty Jr., P.J., Newman, E.M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-08-30
Release date:2006-09-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Calpain 13
To be Published
2IBI
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COVALENT UBIQUITIN-USP2 COMPLEX
Descriptor:Ubiquitin carboxyl-terminal hydrolase 2, Ubiquitin, ZINC ION, ...
Authors:Walker, J.R., Avvakumov, G.V., Bernstein, G., Xue, S., Finerty Jr., P.J., MacKenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-09-11
Release date:2006-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Covalent Ubiquitin-USP2 Complex
To be Published
2NQ3
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN ITCHY HOMOLOG E3 UBIQUITIN PROTEIN LIGASE
Descriptor:Itchy homolog E3 ubiquitin protein ligase, CHLORIDE ION
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-10-30
Release date:2006-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
To be Published
2NQA
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CATALYTIC DOMAIN OF HUMAN CALPAIN 8
Descriptor:Calpain 8, Leupeptin Inhibitor, CALCIUM ION
Authors:Davis, T.L., Paramanathan, R., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-10-30
Release date:2006-11-14
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Human Calpain 8
To be Published
2P0R
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STRUCTURE OF HUMAN CALPAIN 9 IN COMPLEX WITH LEUPEPTIN
Descriptor:Calpain-9, leupeptin, CALCIUM ION
Authors:Davis, T.L., Paramanathan, R., Walker, J.R., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2007-03-01
Release date:2007-03-20
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of Human Minicalpains bound to Inhibitors
To be Published
2P82
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CYSTEINE PROTEASE ATG4A
Descriptor:Cysteine protease ATG4A, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Walker, J.R., Davis, T., Mujib, S., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2007-03-21
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human cysteine protease ATG4A
To be Published
3DL2
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HEXAGONAL STRUCTURE OF THE LDH DOMAIN OF HUMAN UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A
Descriptor:Ubiquitin-conjugating enzyme E2 variant 3, SODIUM ION, PHOSPHATE ION
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Bountra, C., Wolkstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-06-26
Release date:2008-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Investigation Into the L-Lactate Dehydrogenase Domain of Human Ubiquitin-Conjugating Enzyme E2-Like Isoform A.
To be Published
2ESL
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HUMAN CYCLOPHILIN C IN COMPLEX WITH CYCLOSPORIN A
Descriptor:Peptidyl-prolyl cis-trans isomerase C, CYCLOSPORIN A, CALCIUM ION, ...
Authors:Walker, J.R., Davis, T., Newman, E.M., Finerty Jr., P.J., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-10-26
Release date:2005-12-13
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PLoS Biol., 8, 2010
2FK9
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HUMAN PROTEIN KINASE C, ETA
Descriptor:protein kinase C, eta type
Authors:Walker, J.R., Littler, D.R., Finerty Jr., P.J., MacKenzie, F., Newman, E.M., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-01-04
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of human protein kinase C eta (PKCeta) C2 domain and identification of phosphorylation sites.
Biochem.Biophys.Res.Commun., 349, 2006
2GW2
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CRYSTAL STRUCTURE OF THE PEPTIDYL-PROLYL ISOMERASE DOMAIN OF HUMAN CYCLOPHILIN G
Descriptor:Peptidyl-prolyl cis-trans isomerase G, UNKNOWN ATOM OR ION
Authors:Bernstein, G., Tempel, W., Davis, T., Newman, E.M., Finerty Jr., P.J., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-05-03
Release date:2006-06-13
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PLoS Biol., 8, 2010
2HE9
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STRUCTURE OF THE PEPTIDYLPROLYL ISOMERASE DOMAIN OF THE HUMAN NK-TUMOUR RECOGNITION PROTEIN
Descriptor:NK-tumor recognition protein, SULFATE ION
Authors:Walker, J.R., Davis, T., Newman, E.M., MacKenzie, F., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-18
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PLoS Biol., 8, 2010
2HQ6
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STRUCTURE OF THE CYCLOPHILIN_CECYP16-LIKE DOMAIN OF THE SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 10 FROM HOMO SAPIENS
Descriptor:Serologically defined colon cancer antigen 10, IODIDE ION, GLYCEROL
Authors:Walker, J.R., Davis, T., Paramanathan, R., Newman, E.M., Finerty Jr., P.J., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-07-18
Release date:2006-08-01
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PLoS Biol., 8, 2010
2P0C
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CATALYTIC DOMAIN OF THE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE MER
Descriptor:Proto-oncogene tyrosine-protein kinase MER, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Walker, J.R., Huang, X., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2007-02-28
Release date:2007-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the inhibited states of the Mer receptor tyrosine kinase.
J.Struct.Biol., 165, 2009
2A9U
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STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 (USP8)
Descriptor:Ubiquitin carboxyl-terminal hydrolase 8
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, E., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-07-12
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2F4W
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HUMAN UBIQUITIN-CONJUGATING ENZYME E2 J2
Descriptor:ubiquitin-conjugating enzyme E2, J2
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Finerty Jr., P.J., Newman, E.M., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-11-24
Release date:2005-12-27
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2OXE
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STRUCTURE OF THE HUMAN PANCREATIC LIPASE-RELATED PROTEIN 2
Descriptor:Pancreatic lipase-related protein 2, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Walker, J.R., Davis, T., Seitova, A., Finerty Jr., P.J., Butler-Cole, C., Kozieradzki, I., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2007-02-20
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation.
Biochemistry, 47, 2008