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2H77
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BU of 2h77 by Molmil
Crystal structure of human TR alpha bound T3 in monoclinic space group
Descriptor: 3,5,3'TRIIODOTHYRONINE, THRA protein
Authors:Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I.
Deposit date:2006-06-01
Release date:2006-07-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
2H79
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BU of 2h79 by Molmil
Crystal Structure of human TR alpha bound T3 in orthorhombic space group
Descriptor: 3,5,3'TRIIODOTHYRONINE, THRA protein
Authors:Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I.
Deposit date:2006-06-01
Release date:2006-07-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
6AN1
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BU of 6an1 by Molmil
Crystal structure of the complex between PPARgamma LBD and the ligand AM-879
Descriptor: 4-({2-[(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)methyl]phenoxy}methyl)benzoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Veras, H, Figueira, A.C, le Maire, A.
Deposit date:2017-08-11
Release date:2018-02-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.687 Å)
Cite:Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties.
Front Endocrinol (Lausanne), 9, 2018
7UXX
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BU of 7uxx by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein C-terminal domain
Descriptor: ACETATE ION, GLYCEROL, Nucleoprotein
Authors:Bezerra, E.H.S, Tonoli, C.C.C, Soprano, A.S, Franchini, K.G, Trivella, D.B.B, Benedetti, C.E.
Deposit date:2022-05-06
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor.
Sci Rep, 12, 2022
7UXZ
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BU of 7uxz by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein C-terminal domain complexed with Chicoric acid
Descriptor: (2R,3R)-2,3-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}butanedioic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Bezerra, E.H.S, Tonoli, C.C.C, Soprano, A.S, Franchini, K.G, Trivella, D.B.B, Benedetti, C.E.
Deposit date:2022-05-06
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.733 Å)
Cite:Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor.
Sci Rep, 12, 2022
5VWN
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BU of 5vwn by Molmil
Triosephosphate isomerases deletion loop 3 from Trichomonas vaginalis
Descriptor: SODIUM ION, Triosephosphate isomerase
Authors:Lara-Gonzalez, S, Rojas-Mendez, K, Jimenez-Sandoval, P, Estrella-Hernandez, P, Brieba, L.G.
Deposit date:2017-05-22
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:A competent catalytic active site is necessary for substrate induced dimer assembly in triosephosphate isomerase.
Biochim. Biophys. Acta, 1865, 2017
3GWS
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BU of 3gws by Molmil
Crystal Structure of T3-Bound Thyroid Hormone Receptor
Descriptor: 3,5,3'TRIIODOTHYRONINE, Thyroid hormone receptor beta
Authors:Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Polikarpov, I, Baxter, J.D, Webb, P.
Deposit date:2009-04-01
Release date:2009-04-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function
J.Mol.Biol., 360, 2006
3IMY
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BU of 3imy by Molmil
Structure of TR-beta bound to selective thyromimetic GC-1
Descriptor: Thyroid hormone receptor beta, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
Authors:Bleicher, L, Polikarpov, L, Aparicio, R.
Deposit date:2009-08-11
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
BMC STRUCT.BIOL., 8, 2008

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