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7O6W
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BU of 7o6w by Molmil
Crystal structure of (the) VEL1 VEL polymerising domain (I664D mutant)
Descriptor: PHOSPHATE ION, VIN3-like protein 2
Authors:Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
Deposit date:2021-04-12
Release date:2022-11-09
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6V
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BU of 7o6v by Molmil
Crystal structure of the VEL1 VEL polymerising domain (R643A K645D I664D mutant)
Descriptor: VIN3-like protein 2
Authors:Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
Deposit date:2021-04-12
Release date:2022-11-09
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6T
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BU of 7o6t by Molmil
Crystal structure of the polymerising VEL domain of VIN3 (R556D I575D mutant)
Descriptor: MAGNESIUM ION, Protein VERNALIZATION INSENSITIVE 3
Authors:Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
Deposit date:2021-04-12
Release date:2022-11-09
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7OQV
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BU of 7oqv by Molmil
Crystal structure of the polymerising VEL domain of VIN3 (I575D mutant)
Descriptor: Protein VERNALIZATION INSENSITIVE 3
Authors:Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
Deposit date:2021-06-04
Release date:2022-11-09
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6U
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BU of 7o6u by Molmil
Crystal structure of the VIN3 VEL polymerising domain (R554A R556D mutant)
Descriptor: Protein VERNALIZATION INSENSITIVE 3
Authors:Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
Deposit date:2021-04-12
Release date:2022-11-09
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
2VPD
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BU of 2vpd by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
Descriptor: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, ZINC ION
Authors:Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
Deposit date:2008-02-27
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VP7
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BU of 2vp7 by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
Descriptor: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SULFATE ION, ...
Authors:Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
Deposit date:2008-02-26
Release date:2008-06-17
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VPB
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BU of 2vpb by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
Descriptor: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SODIUM ION, ...
Authors:Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
Deposit date:2008-02-27
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VPE
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BU of 2vpe by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
Descriptor: B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ...
Authors:Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
Deposit date:2008-02-27
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VPG
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BU of 2vpg by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
Descriptor: B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ...
Authors:Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Bienz, M, Evans, P.
Deposit date:2008-02-27
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
4WIP
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BU of 4wip by Molmil
DIX domain of human Dvl2
Descriptor: PENTAETHYLENE GLYCOL, Segment polarity protein dishevelled homolog DVL-2
Authors:Fiedler, M, Bienz, M, Madrzak, J, Chin, J.W.
Deposit date:2014-09-26
Release date:2015-05-13
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.
Nat Commun, 6, 2015
7OEX
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BU of 7oex by Molmil
Crystal structure of RBBP9 in complex with phenylalanine
Descriptor: PHENYLALANINE, Serine hydrolase RBBP9
Authors:Fiedler, M, Tang, S, Chin, J.W.
Deposit date:2021-05-04
Release date:2021-12-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Mechanism-based traps enable protease and hydrolase substrate discovery.
Nature, 602, 2022
6RSN
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BU of 6rsn by Molmil
SOSEKI polymerising domain (SOK4 D85A mutant)
Descriptor: SULFATE ION, UPSTREAM OF FLC-like protein (DUF966)
Authors:Fiedler, M, Bienz, M.
Deposit date:2019-05-21
Release date:2020-01-29
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:DIX Domain Polymerization Drives Assembly of Plant Cell Polarity Complexes.
Cell, 180, 2020
7QCE
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BU of 7qce by Molmil
Crystal structure of an atypical PHD finger of VIN3
Descriptor: DI(HYDROXYETHYL)ETHER, VIN3 (Protein VERNALIZATION INSENSITIVE 3), ZINC ION
Authors:Franco-Echevarria, E, Fiedler, M, Dean, C, Bienz, M.
Deposit date:2021-11-23
Release date:2022-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
J.Biol.Chem., 298, 2022
4UP0
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BU of 4up0 by Molmil
Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
Descriptor: HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
Authors:Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
Deposit date:2014-06-11
Release date:2014-11-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
4UP5
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BU of 4up5 by Molmil
Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment
Descriptor: 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
Authors:Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
Deposit date:2014-06-12
Release date:2014-11-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
3ZPV
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BU of 3zpv by Molmil
Crystal structure of Drosophila Pygo PHD finger in complex with Legless HD1 domain
Descriptor: PROTEIN BCL9 HOMOLOG, PROTEIN PYGOPUS, ZINC ION
Authors:Miller, T.C.R, Mieszczanek, J, Sanchez-Barrena, M.J, Rutherford, T.J, Fiedler, M, Bienz, M.
Deposit date:2013-03-02
Release date:2013-10-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Evolutionary Adaptation of the Fly Pygo Phd Finger Towards Recognizing Histone H3 Tail Methylated at Arginine 2
Structure, 21, 2013
8OVY
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BU of 8ovy by Molmil
Structure of analogue of superfolded GFP
Descriptor: Green fluorescent protein
Authors:Dunkelmann, D, Fiedler, M, Bellini, D, Alvira, C.P, Chin, J.W.
Deposit date:2023-04-26
Release date:2024-01-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.537 Å)
Cite:Adding alpha , alpha-disubstituted and beta-linked monomers to the genetic code of an organism.
Nature, 625, 2024
2JDG
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BU of 2jdg by Molmil
Affilin based on HUMAN GAMMA-B CRYSTALLIN
Descriptor: GAMMA CRYSTALLIN B
Authors:Ebersbach, H, Fiedler, E, Scheuermann, T, Fiedler, M, Stubbs, M.T, Reimann, C, Proetzel, G, Rudolph, R, Fiedler, U.
Deposit date:2007-01-08
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein.
J.Mol.Biol., 372, 2007
2JDF
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BU of 2jdf by Molmil
Human gamma-B crystallin
Descriptor: GAMMA CRYSTALLIN B
Authors:Ebersbach, H, Fiedler, E, Scheuermann, T, Fiedler, M, Stubbs, M.T, Reimann, C, Proetzel, G, Rudolph, R, Fiedler, U.
Deposit date:2007-01-08
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein.
J.Mol.Biol., 372, 2007
2XB1
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BU of 2xb1 by Molmil
Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ...
Authors:Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor.
J.Mol.Biol., 401, 2010
7Z06
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BU of 7z06 by Molmil
Structure of YwlG (Q2FF14) from Staphylococcus aureus
Descriptor: SULFATE ION, UPF0340 protein SAUSA300_2068
Authors:Schneider, S, Scheidler, C.M, Sieber, S.A.
Deposit date:2022-02-22
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Bidirectional sequestration between a bacterial hibernation factor and a glutamate metabolizing protein.
Proc.Natl.Acad.Sci.USA, 119, 2022
6JCK
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BU of 6jck by Molmil
Complex structure of Axin-DIX and Dvl2-DIX
Descriptor: Axin-1, Segment polarity protein dishevelled homolog DVL-2
Authors:Yamanishi, K, Shibata, N.
Deposit date:2019-01-29
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:A direct heterotypic interaction between the DIX domains of Dishevelled and Axin mediates signaling to beta-catenin.
Sci.Signal., 12, 2019
5Y3C
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BU of 5y3c by Molmil
Crystal structure of zebrafish Ccd1 DIX domain
Descriptor: Dixin-A
Authors:Terawaki, S, Shibata, N, Higuchi, Y.
Deposit date:2017-07-28
Release date:2017-09-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural basis for Ccd1 auto-inhibition in the Wnt pathway through homomerization of the DIX domain.
Sci Rep, 7, 2017
5Y3B
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BU of 5y3b by Molmil
Crystal structure of mouse Ccd1 DIX domain
Descriptor: Dixin
Authors:Terawaki, S, Shibata, N, Higuchi, Y.
Deposit date:2017-07-28
Release date:2017-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Ccd1 auto-inhibition in the Wnt pathway through homomerization of the DIX domain.
Sci Rep, 7, 2017

 

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