Author results

1CYA
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NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING
Descriptor:CYCLOSPORIN A
Authors:Fesik, S.W.
Deposit date:1992-02-24
Release date:1994-01-31
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:NMR Studies of [U-13C]Cyclosporin a Bound to Cyclophilin: Bound Conformation and Portions of Cyclosporin Involved in Binding.
Biochemistry, 30, 1991
1CYB
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NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING
Descriptor:CYCLOSPORIN A
Authors:Fesik, S.W.
Deposit date:1992-02-24
Release date:1994-01-31
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:NMR Studies of [U-13C]Cyclosporin a Bound to Cyclophilin: Bound Conformation and Portions of Cyclosporin Involved in Binding.
Biochemistry, 30, 1991
1BVH
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SOLUTION STRUCTURE OF A LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE
Descriptor:ACID PHOSPHATASE
Authors:Logan, T.M., Zhou, M.-M., Nettesheim, D.G., Meadows, R.P., Van Etten, R.L., Fesik, S.W.
Deposit date:1994-05-03
Release date:1994-07-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a low molecular weight protein tyrosine phosphatase.
Biochemistry, 33, 1994
1URK
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SOLUTION STRUCTURE OF THE AMINO TERMINAL FRAGMENT OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR
Descriptor:PLASMINOGEN ACTIVATOR, ALPHA-L-FUCOSE
Authors:Hansen, A.P., Petros, A.M., Meadows, R.P., Nettesheim, D.G., Mazar, A.P., Olejniczak, E.T., Xu, R.X., Pederson, T.M., Henkin, J., Fesik, S.W.
Deposit date:1994-01-10
Release date:1995-05-08
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the amino-terminal fragment of urokinase-type plasminogen activator.
Biochemistry, 33, 1994
1PLS
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SOLUTION STRUCTURE OF A PLECKSTRIN HOMOLOGY DOMAIN
Descriptor:PLECKSTRIN HOMOLOGY DOMAIN
Authors:Yoon, H.S., Hajduk, P.J., Petros, A.M., Olejniczak, E.T., Meadows, R.P., Fesik, S.W.
Deposit date:1994-05-03
Release date:1995-06-03
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of a pleckstrin-homology domain.
Nature, 369, 1994
1FLI
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DNA-BINDING DOMAIN OF FLI-1
Descriptor:FLI-1
Authors:Liang, H., Mao, X., Olejniczak, E.T., Nettesheim, D.G., Yu, L., Meadows, R.P., Thompson, C.B., Fesik, S.W.
Deposit date:1994-09-15
Release date:1995-09-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the ets domain of Fli-1 when bound to DNA.
Nat.Struct.Biol., 1, 1994
1YUA
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C-TERMINAL DOMAIN OF ESCHERICHIA COLI TOPOISOMERASE I
Descriptor:TOPOISOMERASE I
Authors:Yu, L., Zhu, C.-X., Tse-Dinh, Y.-C., Fesik, S.W.
Deposit date:1995-03-02
Release date:1996-03-08
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the C-terminal single-stranded DNA-binding domain of Escherichia coli topoisomerase I.
Biochemistry, 34, 1995
1DHM
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DNA-BINDING DOMAIN OF E2 FROM HUMAN PAPILLOMAVIRUS-31, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:E2 PROTEIN
Authors:Liang, H., Petros, A.P., Meadows, R.P., Yoon, H.S., Egan, D.A., Walter, K., Holzman, T.F., Robins, T., Fesik, S.W.
Deposit date:1995-08-15
Release date:1996-12-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the DNA-binding domain of a human papillomavirus E2 protein: evidence for flexible DNA-binding regions.
Biochemistry, 35, 1996
1LXL
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NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE
Descriptor:BCL-XL
Authors:Muchmore, S.W., Sattler, M., Liang, H., Meadows, R.P., Harlan, J.E., Yoon, H.S., Nettesheim, D., Chang, B.S., Thompson, C.B., Wong, S.L., Ng, S.C., Fesik, S.W.
Deposit date:1996-04-04
Release date:1997-04-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1MAZ
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X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH
Descriptor:Bcl-2-like protein 1
Authors:Muchmore, S.W., Sattler, M., Liang, H., Meadows, R.P., Harlan, J.E., Yoon, H.S., Nettesheim, D., Chang, B.S., Thompson, C.B., Wong, S.L., Ng, S.C., Fesik, S.W.
Deposit date:1996-04-09
Release date:1997-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1IRS
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IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:IRS-1, IL-4 RECEPTOR PHOSPHOPEPTIDE
Authors:Zhou, M.-M., Huang, B., Olejniczak, E.T., Meadows, R.P., Shuker, S.B., Miyazaki, M., Trub, T., Shoelson, S.E., Feisk, S.W.
Deposit date:1996-03-22
Release date:1997-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
1SHC
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SHC PTB DOMAIN COMPLEXED WITH A TRKA RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:SHC, TRKA RECEPTOR PHOSPHOPEPTIDE
Authors:Zhou, M.-M., Ravichandran, K.S., Olejniczak, E.T., Petros, A.M., Meadows, R.P., Sattler, M., Harlan, J.E., Wade, W.S., Burakoff, S.J., Fesik, S.W.
Deposit date:1996-03-27
Release date:1997-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Nature, 378, 1995
1TCE
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SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE
Descriptor:SHC, PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR
Authors:Zhou, M.-M., Meadows, R.P., Logan, T.M., Yoon, H.S., Wade, W.R., Ravichandran, K.S., Burakoff, S.J., Feisk, S.W.
Deposit date:1996-03-27
Release date:1997-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor.
Proc.Natl.Acad.Sci.USA, 92, 1995
1BXL
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STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:BCL-XL, BAK PEPTIDE
Authors:Sattler, M., Liang, H., Nettesheim, D., Meadows, R.P., Harlan, J.E., Eberstadt, M., Yoon, H., Shuker, S.B., Chang, B.S., Minn, A.J., Thompson, C.B., Fesik, S.W.
Deposit date:1996-10-16
Release date:1997-10-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
1DDF
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FAS DEATH DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:FAS
Authors:Huang, B., Eberstadt, M., Olejniczak, E., Meadows, R.P., Fesik, S.
Deposit date:1996-11-08
Release date:1997-11-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain.
Nature, 384, 1996
1YUB
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SOLUTION STRUCTURE OF AN RRNA METHYLTRANSFERASE (ERMAM) THAT CONFERS MACROLIDE-LINCOSAMIDE-STREPTOGRAMIN ANTIBIOTIC RESISTANCE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:RRNA METHYLTRANSFERASE
Authors:Yu, L., Petros, A.M., Schnuchel, A., Zhong, P., Severin, J.M., Walter, K., Holzman, T.F., Fesik, S.W.
Deposit date:1997-03-04
Release date:1998-03-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance.
Nat.Struct.Biol., 4, 1997
1A1W
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FADD DEATH EFFECTOR DOMAIN, F25Y MUTANT, NMR MINIMIZED AVERAGE STRUCTURE
Descriptor:FADD PROTEIN
Authors:Eberstadt, M., Huang, B., Chen, Z., Meadows, R.P., Ng, C., Fesik, S.W.
Deposit date:1997-12-18
Release date:1998-12-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.
Nature, 392, 1998
1A1Z
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FADD DEATH EFFECTOR DOMAIN, F25G MUTANT, NMR MINIMIZED AVERAGE STRUCTURE
Descriptor:FADD PROTEIN
Authors:Eberstadt, M., Huang, B., Chen, Z., Meadows, R.P., Ng, C., Fesik, S.W.
Deposit date:1997-12-18
Release date:1998-12-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.
Nature, 392, 1998
1BC9
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CYTOHESIN-1/B2-1 SEC7 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:CYTOHESIN-1
Authors:Betz, S.F., Schnuchel, A., Wang, H., Olejniczak, E.T., Meadows, R.P., Fesik, S.W.
Deposit date:1998-05-06
Release date:1999-05-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the cytohesin-1 (B2-1) Sec7 domain and its interaction with the GTPase ADP ribosylation factor 1.
Proc.Natl.Acad.Sci.USA, 95, 1998
1C9Q
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AVERAGE NMR SOLUTION STRUCTURE OF THE BIR-2 DOMAIN OF XIAP
Descriptor:APOPTOSIS INHIBITOR IAP HOMOLOG, ZINC ION
Authors:Meadows, R.P., Fesik, S.W.
Deposit date:1999-08-03
Release date:2000-08-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP.
Nature, 401, 1999
1FV9
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CRYSTAL STRUCTURE OF HUMAN MICROUROKINASE IN COMPLEX WITH 2-AMINO-5-HYDROXY-BENZIMIDAZOLE
Descriptor:UROKINASE, SULFATE ION, 2-AMINO-5-HYDROXY-BENZIMIDAZOLE
Authors:Nienaber, V.
Deposit date:2000-09-19
Release date:2000-10-18
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Identification of novel inhibitors of urokinase via NMR-based screening.
J.Med.Chem., 43, 2000
1G3F
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NMR STRUCTURE OF A 9 RESIDUE PEPTIDE FROM SMAC/DIABLO COMPLEXED TO THE BIR3 DOMAIN OF XIAP
Descriptor:INHIBITOR OF APOPTOSIS PROTEIN 3, SMAC, ZINC ION
Authors:Liu, Z., Sun, C., Olejniczak, E.T., Meadows, R.P., Betz, S.F., Oost, T., Herrmann, J., Wu, J.C., Fesik, S.W.
Deposit date:2000-10-24
Release date:2001-01-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain.
Nature, 408, 2000
1G5J
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COMPLEX OF BCL-XL WITH PEPTIDE FROM BAD
Descriptor:APOPTOSIS REGULATOR BCL-X, BAD PROTEIN
Authors:Petros, A.M., Nettesheim, D.G., Wang, Y., Olejniczak, E.T., Meadows, R.P., Mack, J., Swift, K., Matayoshi, E.D., Zhang, H., Thompson, C.B., Fesik, S.W.
Deposit date:2000-11-01
Release date:2001-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.
Protein Sci., 9, 2000
1G5M
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HUMAN BCL-2, ISOFORM 1
Descriptor:PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN)
Authors:Petros, A.M., Medek, A., Nettesheim, D.G., Kim, D.H., Yoon, H.S., Swift, K., Matayoshi, E.D., Oltersdorf, T., Fesik, S.W.
Deposit date:2000-11-01
Release date:2001-03-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the antiapoptotic protein bcl-2.
Proc.Natl.Acad.Sci.USA, 98, 2001
1I3O
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CRYSTAL STRUCTURE OF THE COMPLEX OF XIAP-BIR2 AND CASPASE 3
Descriptor:CASPASE 3, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, ZINC ION
Authors:Riedl, S.J., Renatus, M., Schwarzenbacher, R., Zhou, Q., Sun, C., Fesik, S.W., Liddington, R.C., Salvesen, G.S.
Deposit date:2001-02-15
Release date:2001-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the inhibition of caspase-3 by XIAP.
Cell(Cambridge,Mass.), 104, 2001