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3OV9
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BU of 3ov9 by Molmil
Structure of the Nucleoprotein from Rift Valley Fever Virus
Descriptor: NITRITE ION, Nucleoprotein, SODIUM ION
Authors:Ferron, F, Danek, E.I, Li, Z, Luo, D, Wong, Y.H, Coutard, B, Lantez, V, Charrel, R, Canard, B, Walz, T, Lescar, J.
Deposit date:2010-09-16
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3OUO
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BU of 3ouo by Molmil
Structure of the Nucleoprotein from Rift Valley Fever Virus
Descriptor: NITRITE ION, Nucleoprotein
Authors:Ferron, F, Danek, E.I, Li, Z, Luo, D, Wong, Y.H, Coutard, B, Lantez, V, Charrel, R, Canard, B, Walz, T, Lescar, J.
Deposit date:2010-09-15
Release date:2011-05-25
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
8C0G
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BU of 8c0g by Molmil
SARS-CoV nsp16-nsp10 complexed with N7-GTP
Descriptor: DI(HYDROXYETHYL)ETHER, Non-structural protein 7, SODIUM ION, ...
Authors:Ferron, F, Debarnot, C, Coutard, B, Canard, B, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2022-12-16
Release date:2023-12-27
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Observation of N7-GTP in nsp16-nsp10 Sars-CoV
To Be Published
5NFY
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BU of 5nfy by Molmil
SARS-CoV nsp10/nsp14 dynamic complex
Descriptor: DI(HYDROXYETHYL)ETHER, Polyprotein 1ab, ZINC ION
Authors:Ferron, F, Gluais, L, Vonrhein, C, Bricogne, G, Canard, B, Imbert, I.
Deposit date:2017-03-16
Release date:2018-01-10
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.382 Å)
Cite:Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2PBD
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BU of 2pbd by Molmil
Ternary complex of profilin-actin with the poly-PRO-GAB domain of VASP*
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Ferron, F, Rebowski, G, Dominguez, R.
Deposit date:2007-03-28
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP
Embo J., 26, 2007
2PAV
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BU of 2pav by Molmil
Ternary complex of Profilin-Actin with the Last Poly-Pro of Human VASP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Ferron, F, Rebowski, G, Dominguez, R.
Deposit date:2007-03-27
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.
Embo J., 26, 2007
6YU8
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BU of 6yu8 by Molmil
RNA Methyltransferase of Sudan Ebola Virus
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Ferron, F, Valle, C, Zamboni, V, Canard, B, Decroly, E.
Deposit date:2020-04-25
Release date:2021-02-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.841 Å)
Cite:First insights into the structural features of Ebola virus methyltransferase activities.
Nucleic Acids Res., 49, 2021
7Z05
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BU of 7z05 by Molmil
White Bream virus N7-Methyltransferase
Descriptor: DI(HYDROXYETHYL)ETHER, Non-structural protein 1, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Shannon, A, Gauffre, P, Canard, B, Ferron, F.
Deposit date:2022-02-22
Release date:2022-09-28
Last modified:2022-11-16
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome.
Nucleic Acids Res., 50, 2022
7Z2J
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BU of 7z2j by Molmil
White Bream virus N7-Methyltransferase
Descriptor: Non-structural protein 1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Shannon, A, Gauffre, P, Canard, B, Ferron, F.
Deposit date:2022-02-28
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.657 Å)
Cite:A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome.
Nucleic Acids Res., 50, 2022
1QZ8
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BU of 1qz8 by Molmil
Crystal structure of SARS coronavirus NSP9
Descriptor: SULFATE ION, polyprotein 1ab
Authors:Egloff, M.P, Ferron, F, Campanacci, V, Longhi, S, Rancurel, C, Dutartre, H, Snijder, E.J, Gorbalenya, A.E, Cambillau, C, Canard, B.
Deposit date:2003-09-16
Release date:2004-02-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world.
Proc.Natl.Acad.Sci.USA, 101, 2004
8RCQ
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BU of 8rcq by Molmil
Structural flexibility of Nucleoprotein of the Toscana virus in the presence of a nanobody.
Descriptor: Nucleoprotein, VHH
Authors:Papageorgiou, N, Ferron, F, Coutard, B, Lichiere, J, Baklouti, A.
Deposit date:2023-12-06
Release date:2024-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural flexibility of Toscana virus nucleoprotein in the presence of a single-chain camelid antibody.
Acta Crystallogr D Struct Biol, 80, 2024
5FVA
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BU of 5fva by Molmil
Toscana Virus Nucleocapsid Protein
Descriptor: NUCLEOPROTEIN, SODIUM ION
Authors:Baklouti, A, Sevajol, M, Goulet, A, Lichiere, J, Ferron, F, Canard, B, Charrel, R.N, Coutard, B, Papageorgiou, N.
Deposit date:2016-02-03
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Toscana virus nucleoprotein oligomer organization observed in solution.
Acta Crystallogr D Struct Biol, 73, 2017
4UD1
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BU of 4ud1 by Molmil
Structure of the N Terminal domain of the MERS CoV nucleocapsid
Descriptor: AMMONIUM ION, GLYCEROL, IMIDAZOLE, ...
Authors:Papageorgiou, N, Lichiere, J, Ferron, F, Canard, B, Coutard, B.
Deposit date:2014-12-05
Release date:2015-12-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Characterization of the N-Terminal Part of the Mers-Cov Nucleocapsid by X-Ray Diffraction and Small-Angle X-Ray Scattering
Acta Crystallogr.,Sect.D, 72, 2016
2EYN
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BU of 2eyn by Molmil
Crystal structure of the actin-binding domain of human alpha-actinin 1 at 1.8 Angstrom resolution
Descriptor: Alpha-actinin 1
Authors:Borrego-Diaz, E, Kerff, F, Lee, S.H, Ferron, F, Li, Y, Dominguez, R.
Deposit date:2005-11-09
Release date:2006-08-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the actin-binding domain of alpha-actinin 1: Evaluating two competing actin-binding models.
J.Struct.Biol., 155, 2006
2EYI
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BU of 2eyi by Molmil
Crystal structure of the actin-binding domain of human alpha-actinin 1 at 1.7 Angstrom resolution
Descriptor: Alpha-actinin 1
Authors:Borrego-Diaz, E, Kerff, F, Lee, S.H, Ferron, F, Li, Y, Dominguez, R.
Deposit date:2005-11-09
Release date:2006-08-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the actin-binding domain of alpha-actinin 1: Evaluating two competing actin-binding models.
J.Struct.Biol., 155, 2006
8BCR
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BU of 8bcr by Molmil
DENV3 Methyltransferase in complexed with AT-9010 and SAH
Descriptor: Genome polyprotein, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Gauffre, P, Fattorini, V, Canard, B, Ferron, F.
Deposit date:2022-10-17
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5.
Antiviral Res., 212, 2023
7OA4
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BU of 7oa4 by Molmil
Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001
Descriptor: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, FORMIC ACID, MANGANESE (II) ION, ...
Authors:Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K.
Deposit date:2021-04-19
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001
To Be Published
5T2T
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BU of 5t2t by Molmil
Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease bound to compound L742001
Descriptor: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, CHLORIDE ION, GLYCEROL, ...
Authors:Saez-Ayala, M, Yekwa, E.L, Canard, B, Alvarez, K, Ferron, F.
Deposit date:2016-08-24
Release date:2017-09-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.967 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
7PLR
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BU of 7plr by Molmil
Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir
Descriptor: Baloxavir acid, FORMIC ACID, GLYCEROL, ...
Authors:Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K.
Deposit date:2021-09-01
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir
To Be Published
7ED5
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BU of 7ed5 by Molmil
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Descriptor: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
Authors:Shannon, A, Fattorini, V, Sama, B, Selisko, B, Feracci, M, Falcou, C, Gauffre, P, El Kazzi, P, Delpal, A, Decroly, E, Alvarez, K, Eydoux, C, Guillemot, J.-C, Moussa, A, Good, S, Colla, P, Lin, K, Sommadossi, J.-P, Zhu, Y.X, Yan, X.D, Shi, H, Ferron, F, Canard, B.
Deposit date:2021-03-15
Release date:2022-02-16
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Nat Commun, 13, 2022
8CB3
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BU of 8cb3 by Molmil
SARS-CoV Macro domain complexed with 3-(N-morpholino)propanesulfonic acid
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, Papain-like protease nsp3
Authors:Morin, B, Ferron, F, Coutard, B, Canard, B, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2023-01-25
Release date:2024-02-07
Method:X-RAY DIFFRACTION (1.572 Å)
Cite:SARS-CoV Macro domain complexed with 3-(N-morpholino)propanesulfonic acid
To Be Published
2D1L
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BU of 2d1l by Molmil
Structure of F-actin binding domain IMD of MIM (Missing In Metastasis)
Descriptor: Metastasis suppressor protein 1
Authors:Lee, S.H, Kerff, F, Chereau, D, Ferron, F, Dominguez, R.
Deposit date:2005-08-27
Release date:2006-09-12
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for the actin-binding function of missing-in-metastasis
Structure, 15, 2007
2XYV
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BU of 2xyv by Molmil
Crystal structure of the nsp16 nsp10 SARS coronavirus complex
Descriptor: CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ...
Authors:Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B.
Deposit date:2010-11-19
Release date:2011-10-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
2XYQ
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BU of 2xyq by Molmil
Crystal structure of the nsp16 nsp10 SARS coronavirus complex
Descriptor: CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ...
Authors:Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B.
Deposit date:2010-11-18
Release date:2011-10-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
2XYR
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BU of 2xyr by Molmil
Crystal structure of the nsp16 nsp10 SARS coronavirus complex
Descriptor: CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ...
Authors:Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B.
Deposit date:2010-11-18
Release date:2011-10-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011

 

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