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4BQM
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BU of 4bqm by Molmil
Crystal structure of human liver-type glutaminase, catalytic domain
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLUTAMINASE LIVER ISOFORM, ...
Authors:Ferreira, I.M, Vollmar, M, Krojer, T, Strain-Damerell, C, Froese, S, Coutandin, D, Williams, E, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Dias, S.M.G, Ambrosio, A.L.B, Yue, W.W.
Deposit date:2013-05-31
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain
To be Published
5U0K
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BU of 5u0k by Molmil
C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA)
Descriptor: Glutaminase liver isoform, mitochondrial
Authors:Ferreira, I.M, Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.548 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
7Q0S
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BU of 7q0s by Molmil
Human GYS1-GYG1 complex inhibited-like state bound to glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase, muscle, ...
Authors:McCorvie, T.J, Shrestha, L, Froese, D.S, Ferreira, I.M, Yue, W.W.
Deposit date:2021-10-16
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.
Nat.Struct.Mol.Biol., 29, 2022
7Q0B
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BU of 7q0b by Molmil
Human GYS1-GYG1 complex inhibited state
Descriptor: Glycogen [starch] synthase, muscle, Glycogenin-1
Authors:McCorvie, T.J, Shrestha, L, Froese, D.S, Ferreira, I.M, Yue, W.W.
Deposit date:2021-10-14
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.
Nat.Struct.Mol.Biol., 29, 2022
7Q12
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BU of 7q12 by Molmil
Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase, muscle, ...
Authors:McCorvie, T.J, Shrestha, L, Froese, D.S, Ferreira, I.M, Yue, W.W.
Deposit date:2021-10-17
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.
Nat.Struct.Mol.Biol., 29, 2022
7Q13
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BU of 7q13 by Molmil
Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate, uridine diphosphate, and glucose
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase, muscle, ...
Authors:McCorvie, T.J, Shrestha, L, Froese, D.S, Ferreira, I.M, Yue, W.W.
Deposit date:2021-10-17
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.
Nat.Struct.Mol.Biol., 29, 2022
4JKT
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BU of 4jkt by Molmil
Crystal structure of mouse Glutaminase C, BPTES-bound form
Descriptor: Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
Authors:Fornezari, C, Ferreira, A.P.S, Dias, S.M.G, Ambrosio, A.L.B.
Deposit date:2013-03-11
Release date:2013-08-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor.
J.Biol.Chem., 288, 2013
3SS5
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BU of 3ss5 by Molmil
Crystal structure of mouse Glutaminase C, L-glutamate-bound form
Descriptor: GLUTAMIC ACID, Glutaminase C
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS4
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BU of 3ss4 by Molmil
Crystal structure of mouse Glutaminase C, phosphate-bound form
Descriptor: Glutaminase C, PHOSPHATE ION
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS3
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BU of 3ss3 by Molmil
Crystal structure of mouse Glutaminase C, ligand-free form
Descriptor: CHLORIDE ION, Glutaminase C
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
5U0J
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BU of 5u0j by Molmil
C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - monoclinic crystal form
Descriptor: Glutaminase kidney isoform, mitochondrial, SODIUM ION
Authors:Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5U0I
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BU of 5u0i by Molmil
C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - tetragonal crystal form
Descriptor: CHLORIDE ION, Glutaminase kidney isoform, mitochondrial, ...
Authors:Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.423 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5UQE
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BU of 5uqe by Molmil
Multidomain structure of human kidney-type glutaminase(KGA/GLS)
Descriptor: Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
Authors:Pasquali, C.C, Dias, S.M.G, Ambrosio, A.L.B.
Deposit date:2017-02-08
Release date:2017-05-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017

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