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4TVM
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BU of 4tvm by Molmil
Structure of Citrate Synthase from Mycobacterium tuberculosis
Descriptor: Citrate synthase, OXALOACETATE ION
Authors:Ferraris, D.M, Rizzi, M.
Deposit date:2014-06-27
Release date:2015-01-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis.
Proteins, 83, 2015
4TVO
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BU of 4tvo by Molmil
Structure of Malate Dehydrogenase from Mycobacterium tuberculosis
Descriptor: Malate dehydrogenase, SODIUM ION, SULFATE ION
Authors:Ferraris, D.M, Rizzi, M.
Deposit date:2014-06-27
Release date:2015-01-14
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis.
Proteins, 83, 2015
6R76
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BU of 6r76 by Molmil
Crystal structure of trans-3-Hydroxy-L-proline dehydratase from Thermococcus litoralis - open conformation
Descriptor: Proline racemase
Authors:Ferraris, D.M, Miggiano, R, Rizzi, M.
Deposit date:2019-03-28
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form.
Biochem.Biophys.Res.Commun., 516, 2019
6R77
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BU of 6r77 by Molmil
Crystal structure of trans-3-Hydroxy-L-proline dehydratase in complex with substrate - closed conformation
Descriptor: 3-HYDROXYPROLINE, Proline racemase
Authors:Ferraris, D.M, Miggiano, R, Rizzi, M.
Deposit date:2019-03-28
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form.
Biochem.Biophys.Res.Commun., 516, 2019
3ZUK
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BU of 3zuk by Molmil
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ZINC METALLOPROTEASE ZMP1 IN COMPLEX WITH INHIBITOR
Descriptor: 2,2',2''-NITRILOTRIETHANOL, ACETATE ION, CALCIUM ION, ...
Authors:Ferraris, D.M, Sbardella, D, Petrera, A, Marini, S, Amstutz, B, Coletta, M, Sander, P, Rizzi, M.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Mycobacterium Tuberculosis Zinc-Dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity.
J.Biol.Chem., 286, 2011
2WQW
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BU of 2wqw by Molmil
DOUBLE-DISULFIDE CROSS-LINKED CRYSTAL DIMER of the Listeria monocytogenes InlB internalin domain
Descriptor: DI(HYDROXYETHYL)ETHER, INTERNALIN B
Authors:Ferraris, D.M, Heinz, D.W, Niemann, H.H.
Deposit date:2009-08-27
Release date:2009-11-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Ligand-Mediated Dimerization of the met Receptor Tyrosine Kinase by the Bacterial Invasion Protein Inlb.
J.Mol.Biol., 395, 2010
4LVQ
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BU of 4lvq by Molmil
Crystal structure of the M. tuberculosis phosphate binding protein PstS3
Descriptor: PHOSPHATE ION, Phosphate-binding protein PstS 3
Authors:Ferraris, D.M, Rizzi, M.
Deposit date:2013-07-26
Release date:2014-03-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3.
Proteins, 82, 2014
6T3E
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BU of 6t3e by Molmil
Structure of Thermococcus litoralis Delta(1)-pyrroline-2-carboxylate reductase in complex with NADH and L-proline
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DELTA1-pyrroline-2-carboxylate reductase, PROLINE
Authors:Ferraris, D.M, Miggiano, R, Ferrario, E, Rizzi, M.
Deposit date:2019-10-10
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Thermococcus litoralis Delta1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline.
Acta Crystallogr D Struct Biol, 76, 2020
2WQX
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BU of 2wqx by Molmil
InlB321_4R: S199R, D200R, G206R, A227R, C242A mutant of the Listeria monocytogenes InlB internalin domain
Descriptor: INTERNALIN B
Authors:Niemann, H.H, Ferraris, D.M, Heinz, D.W.
Deposit date:2009-08-27
Release date:2009-11-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Ligand-Mediated Dimerization of the met Receptor Tyrosine Kinase by the Bacterial Invasion Protein Inlb.
J.Mol.Biol., 395, 2010
7Z6C
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BU of 7z6c by Molmil
Crystal structure of human Dihydroorotate Dehydrogenase in complex with the inhibitor 2-Hydroxy-N-(2-ispropyl-5-methyl-4-phenoxyphenyl)pyrazolo[1,5-a]pyridine-3-carboxamide.
Descriptor: ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Alberti, M, Lolli, M.L, Boschi, D, Sainas, S, Rizzi, M, Ferraris, D.M, Miggiano, R.
Deposit date:2022-03-11
Release date:2022-10-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a ]pyridine Scaffold: SAR of the Aryloxyaryl Moiety.
J.Med.Chem., 65, 2022
7QPO
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BU of 7qpo by Molmil
Crystal structure of human trans-3-Hydroxy-L-proline dehydratase
Descriptor: Trans-3-hydroxy-L-proline dehydratase
Authors:Ferrario, E, Miggiano, R, Rizzi, M, Ferraris, D.M.
Deposit date:2022-01-05
Release date:2022-08-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:The integration of AlphaFold-predicted and crystal structures of human trans -3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism.
Comput Struct Biotechnol J, 20, 2022
8OFW
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BU of 8ofw by Molmil
Crystal structure of the full-length dihydroorotate dehydrogenase from Mycobacterium tuberculosis
Descriptor: Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE
Authors:Alberti, M, Ferraris, D.M, Miggiano, R.
Deposit date:2023-03-17
Release date:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor.
Febs Lett., 597, 2023
2C0G
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BU of 2c0g by Molmil
Structure of PDI-related Chaperone, Wind mutant-Y53S
Descriptor: CHLORIDE ION, SODIUM ION, WINDBEUTEL PROTEIN
Authors:Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M.
Deposit date:2005-09-02
Release date:2006-08-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants.
Acta Crystallogr.,Sect.D, 62, 2006
2C0F
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BU of 2c0f by Molmil
Structure of Wind Y53F mutant
Descriptor: WINDBEUTEL PROTEIN
Authors:Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M.
Deposit date:2005-09-02
Release date:2006-08-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants.
Acta Crystallogr.,Sect.D, 62, 2006
2C0E
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BU of 2c0e by Molmil
Structure of PDI-related Chaperone, Wind with his-tag on C-terminus.
Descriptor: WINDBEUTEL PROTEIN
Authors:Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M.
Deposit date:2005-09-01
Release date:2006-08-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants.
Acta Crystallogr.,Sect.D, 62, 2006
2C1Y
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BU of 2c1y by Molmil
Structure of PDI-related Chaperone, Wind mutant-Y55K
Descriptor: WINDBEUTEL PROTEIN
Authors:Sevvana, M, Ma, Q, Barnewitz, K, Guo, C, Soling, H.-D, Ferrari, D.M, Sheldrick, G.M.
Deposit date:2005-09-22
Release date:2006-08-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Elucidation of the Pdi-Related Chaperone Wind with the Help of Mutants.
Acta Crystallogr.,Sect.D, 62, 2006
2QC7
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BU of 2qc7 by Molmil
Crystal structure of the protein-disulfide isomerase related chaperone ERp29
Descriptor: Endoplasmic reticulum protein ERp29
Authors:Barak, N.N, Sevvana, M, Neumann, P, Malesevic, M, Naumann, K, Fischer, G, Sheldrick, G.M, Stubbs, M.T, Ferrari, D.M.
Deposit date:2007-06-19
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29.
J.Mol.Biol., 385, 2009
6S6W
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BU of 6s6w by Molmil
Crystal Structure of human ALDH1A3 in complex with 2,6-diphenylimidazo[1,2-a]pyridine (compound GA11) and NAD+
Descriptor: 2,6-diphenylimidazo[1,2-a]pyridine, Aldehyde dehydrogenase family 1 member A3, GLYCEROL, ...
Authors:Gelardi, E.L.M, Quattrini, L, LaMotta, C, Ferraris, D.M, Garavaglia, S.
Deposit date:2019-07-03
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells.
J.Med.Chem., 63, 2020
5MP7
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BU of 5mp7 by Molmil
Crystal structure of phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis
Descriptor: ACETATE ION, Ribose-phosphate pyrophosphokinase
Authors:Donini, S, Garavaglia, S, Ferraris, D.M, Miggiano, R, Mori, S, Shibayama, K, Rizzi, M.
Deposit date:2016-12-16
Release date:2017-04-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis.
PLoS ONE, 12, 2017
5HKF
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BU of 5hkf by Molmil
Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Orotate phosphoribosyltransferase
Authors:Donini, S, Ferraris, D.M, Bolognesi, G, Rizzi, M.
Deposit date:2016-01-14
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.
Sci Rep, 7, 2017
5HKI
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BU of 5hki by Molmil
Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with Fe(III) dicitrate
Descriptor: Iron(III) dicitrate, Orotate phosphoribosyltransferase
Authors:Donini, S, Ferraris, D.M, Bolognesi, G, Rizzi, M.
Deposit date:2016-01-14
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.
Sci Rep, 7, 2017
3UJ1
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BU of 3uj1 by Molmil
Crystal structure of the third thioredoxin domain of human ERp46
Descriptor: Thioredoxin domain-containing protein 5
Authors:Parthier, C, Funkner, A, Ferrari, D.M, Stubbs, M.T.
Deposit date:2011-11-07
Release date:2012-11-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:Peptide Binding by Catalytic Domains of the Protein Disulfide Isomerase-Related Protein ERp46.
J.Mol.Biol., 425, 2013
1OVN
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BU of 1ovn by Molmil
Crystal Structure and Functional Analysis of Drosophila Wind-- a PDI-Related Protein
Descriptor: CESIUM ION, Windbeutel
Authors:Ma, Q, Guo, C, Barnewitz, K, Sheldrick, G.M, Soling, H.D, Uson, I, Ferrari, D.M.
Deposit date:2003-03-27
Release date:2004-02-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and functional analysis of Drosophila Wind, a protein-disulfide isomerase-related protein.
J.Biol.Chem., 278, 2003
2WQV
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BU of 2wqv by Molmil
Internalin domain of Listeria monocytogenes InlB: rhombohedral crystal form
Descriptor: INTERNALIN B, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL
Authors:Niemann, H.H, Heinz, D.W.
Deposit date:2009-08-27
Release date:2009-11-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ligand-Mediated Dimerization of the met Receptor Tyrosine Kinase by the Bacterial Invasion Protein Inlb.
J.Mol.Biol., 395, 2010
2WQU
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BU of 2wqu by Molmil
Internalin domain of Listeria monocytogenes InlB: triclinic crystal form
Descriptor: GLYCEROL, INTERNALIN B, SULFATE ION
Authors:Niemann, H.H, Heinz, D.W.
Deposit date:2009-08-27
Release date:2009-11-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ligand-Mediated Dimerization of the met Receptor Tyrosine Kinase by the Bacterial Invasion Protein Inlb.
J.Mol.Biol., 395, 2010

 

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