Author results

1BQQ
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CRYSTAL STRUCTURE OF THE MT1-MMP--TIMP-2 COMPLEX
Descriptor:MEMBRANE-TYPE MATRIX METALLOPROTEINASE, METALLOPROTEINASE INHIBITOR 2, CALCIUM ION, ...
Authors:Fernandez-Catalan, C., Bode, W., Huber, R., Turk, D., Calvete, J.J., Lichte, A., Tschesche, H., Maskos, K.
Deposit date:1998-08-18
Release date:1999-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor.
EMBO J., 17, 1998
1BUV
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CRYSTAL STRUCTURE OF THE MT1-MMP-TIMP-2 COMPLEX
Descriptor:PROTEIN (MEMBRANE-TYPE MATRIX METALLOPROTEINASE (CDMT1-MMP)), PROTEIN (METALLOPROTEINASE INHIBITOR (TIMP-2)), CALCIUM ION, ...
Authors:Fernandez-Catalan, C., Bode, W., Huber, R., Turk, D., Calvete, J.J., Lichte, A., Tschesche, H., Maskos, K.
Deposit date:1998-09-07
Release date:1999-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor.
EMBO J., 17, 1998
1KFU
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CRYSTAL STRUCTURE OF HUMAN M-CALPAIN FORM II
Descriptor:M-CALPAIN LARGE SUBUNIT, M-CALPAIN SMALL SUBUNIT
Authors:Strobl, S., Fernandez-Catalan, C., Braun, M., Huber, R., Masumoto, H., Nakagawa, K., Irie, A., Sorimachi, H., Bourenkow, G., Bartunik, H., Suzuki, K., Bode, W.
Deposit date:2001-11-23
Release date:2001-12-07
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.
Proc.Natl.Acad.Sci.USA, 97, 2000
1KFX
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CRYSTAL STRUCTURE OF HUMAN M-CALPAIN FORM I
Descriptor:M-CALPAIN LARGE SUBUNIT, M-CALPAIN SMALL SUBUNIT
Authors:Strobl, S., Fernandez-Catalan, C., Braun, M., Huber, R., Masumoto, H., Nakagawa, K., Irie, A., Sorimachi, H., Bourenkow, G., Bartunik, H., Suzuki, K., Bode, W.
Deposit date:2001-11-23
Release date:2001-12-07
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.
Proc.Natl.Acad.Sci.USA, 97, 2000
1BD8
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STRUCTURE OF CDK INHIBITOR P19INK4D
Descriptor:P19INK4D CDK4/6 INHIBITOR
Authors:Baumgartner, R., Fernandez-Catalan, C., Winoto, A., Huber, R., Engh, R., Holak, T.A.
Deposit date:1998-05-12
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human cyclin-dependent kinase inhibitor p19INK4d: comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16INK4a.
Structure, 6, 1998
1BKC
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CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE)
Descriptor:TUMOR NECROSIS FACTOR-ALPHA-CONVERTING ENZYME, ZINC ION, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide
Authors:Maskos, K., Fernandez-Catalan, C., Bode, W.
Deposit date:1998-04-23
Release date:1999-06-22
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BUI
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STRUCTURE OF THE TERNARY MICROPLASMIN-STAPHYLOKINASE-MICROPLASMIN COMPLEX: A PROTEINASE-COFACTOR-SUBSTRATE COMPLEX IN ACTION
Descriptor:Plasminogen, Staphylokinase, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide
Authors:Parry, M.A.A., Fernandez-Catalan, C., Bergner, A., Huber, R., Hopfner, K., Schlott, B., Guehrs, K., Bode, W.
Deposit date:1998-09-04
Release date:1999-09-02
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action.
Nat.Struct.Biol., 5, 1998
1DTD
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE LEECH CARBOXYPEPTIDASE INHIBITOR AND THE HUMAN CARBOXYPEPTIDASE A2 (LCI-CPA2)
Descriptor:CARBOXYPEPTIDASE A2, METALLOCARBOXYPEPTIDASE INHIBITOR, ZINC ION, ...
Authors:Reverter, D., Fernandez-Catalan, C., Bode, W., Holak, T.A., Aviles, F.X.
Deposit date:2000-01-12
Release date:2000-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat.Struct.Biol., 7, 2000
1DTV
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NMR STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR (LCI)
Descriptor:CARBOXYPEPTIDASE INHIBITOR
Authors:Reverter, D., Fernandez-Catalan, C., Bode, W., Holak, T.A., Aviles, F.X.
Deposit date:2000-01-13
Release date:2000-07-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat.Struct.Biol., 7, 2000
1Q2L
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CRYSTAL STRUCTURE OF PITRILYSIN
Descriptor:Protease III, ZINC ION, PLATINUM (II) ION
Authors:Maskos, K., Jozic, D., Fernandez-Catalan, C.
Deposit date:2003-07-25
Release date:2005-05-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of pitrilysin, the prototype of insulin-degrading enzymes
To be Published
1BQB
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AUREOLYSIN, STAPHYLOCOCCUS AUREUS METALLOPROTEINASE
Descriptor:PROTEIN (AUREOLYSIN), ZINC ION, CALCIUM ION
Authors:Medrano, F.J., Banbula, A., Potempa, J., Travis, J., Bode, W.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution.
Structure, 6, 1998
1BR9
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HUMAN TISSUE INHIBITOR OF METALLOPROTEINASE-2
Descriptor:METALLOPROTEINASE-2 INHIBITOR
Authors:Tuuttila, A., Morgunova, E., Bergmann, U., Lindqvist, Y., Tryggvason, K., Schneider, G.
Deposit date:1998-08-28
Release date:1999-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 A resolution.
J.Mol.Biol., 284, 1998
1QRZ
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CATALYTIC DOMAIN OF PLASMINOGEN
Descriptor:PLASMINOGEN
Authors:Peisach, E., Wang, J., de los Santos, T., Reich, E., Ringe, D.
Deposit date:1999-06-16
Release date:1999-10-14
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the proenzyme domain of plasminogen.
Biochemistry, 38, 1999
1ZFI
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SOLUTION STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR
Descriptor:Metallocarboxypeptidase inhibitor
Authors:Arolas, J.L., D'Silva, L., Popowicz, G.M., Aviles, F.X., Holak, T.A., Ventura, S.
Deposit date:2005-04-20
Release date:2005-09-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
1ZFL
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SOLUTION STRUCTURE OF III-A, THE MAJOR INTERMEDIATE IN THE OXIDATIVE FOLDING OF LEECH CARBOXYPEPTIDASE INHIBITOR
Descriptor:Metallocarboxypeptidase inhibitor
Authors:Arolas, J.L., D'Silva, L., Popowicz, G.M., Aviles, F.X., Holak, T.A., Ventura, S.
Deposit date:2005-04-20
Release date:2005-09-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
2ABZ
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CRYSTAL STRUCTURE OF C19A/C43A MUTANT OF LEECH CARBOXYPEPTIDASE INHIBITOR IN COMPLEX WITH BOVINE CARBOXYPEPTIDASE A
Descriptor:Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L., Popowicz, G.M., Bronsoms, S., Aviles, F.X., Huber, R., Holak, T.A., Ventura, S.
Deposit date:2005-07-18
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352, 2005
3DF0
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CALCIUM-DEPENDENT COMPLEX BETWEEN M-CALPAIN AND CALPASTATIN
Descriptor:Calpain-2 catalytic subunit, Calpain small subunit 1, Calpastatin, ...
Authors:Moldoveanu, T., Gehring, K., Green, D.R.
Deposit date:2008-06-11
Release date:2008-11-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.
Nature, 456, 2008