Author results

1FI1
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FHUA IN COMPLEX WITH LIPOPOLYSACCHARIDE AND RIFAMYCIN CGP4832
Descriptor:FERRICHROME-IRON RECEPTOR, 2-amino-2-deoxy-alpha-D-glucopyranose, 3-DEOXY-D-GLUCOSAMINE, ...
Authors:Ferguson, A.D., Koedding, J., Boes, C., Walker, G., Coulton, J.W., Diederichs, K., Braun, V., Welte, W.
Deposit date:2000-08-03
Release date:2001-08-29
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Active transport of an antibiotic rifamycin derivative by the outer-membrane protein FhuA.
Structure, 9, 2001
1QFF
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E. COLI FERRIC HYDROXAMATE UPTAKE RECEPTOR (FHUA) IN COMPLEX WITH BOUND FERRICHROME-IRON
Descriptor:FERRIC HYDROXAMATE UPTAKE RECEPTOR, 2-amino-2-deoxy-alpha-D-glucopyranose, 3-DEOXY-D-GLUCOSAMINE, ...
Authors:Ferguson, A.D., Hofmann, E., Coulton, J.W., Diederichs, K., Welte, W.
Deposit date:1999-04-10
Release date:2000-07-26
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins.
Structure Fold.Des., 8, 2000
1QFG
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E. COLI FERRIC HYDROXAMATE RECEPTOR (FHUA)
Descriptor:PROTEIN (FERRIC HYDROXAMATE UPTAKE RECEPTOR), 2-amino-2-deoxy-alpha-D-glucopyranose, 3-DEOXY-D-GLUCOSAMINE, ...
Authors:Ferguson, A.D., Welte, W., Hofmann, E., Lindner, B., Holst, O., Coulton, J.W., Diederichs, K.
Deposit date:1999-04-10
Release date:2000-07-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins.
Structure Fold.Des., 8, 2000
1QJQ
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FERRIC HYDROXAMATE RECEPTOR FROM ESCHERICHIA COLI (FHUA)
Descriptor:FERRIC HYDROXAMATE RECEPTOR, 3-DEOXY-D-GLUCOSAMINE, 3-DEOXY-D-MANNO-OCT-2-ULOSONIC ACID, ...
Authors:Ferguson, A.D., Braun, V., Fiedler, H.-P., Coulton, J.W., Diederichs, K., Welte, W.
Deposit date:1999-06-29
Release date:2000-06-05
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structure of the Antibiotic Albomycin in Complex with the Outer Membrane Protein Fhua
Protein Sci., 9, 2000
1QKC
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ESCHERICHIA COLI FERRIC HYDROXAMATE UPTAKE RECEPTOR (FHUA) IN COMPLEX DELTA TWO-ALBOMYCIN
Descriptor:FERRIC HYDROXAMATE RECEPTOR, 2-amino-2-deoxy-alpha-D-glucopyranose, 3-DEOXY-D-GLUCOSAMINE, ...
Authors:Ferguson, A.D., Braun, V., Fiedler, H.-P., Coulton, J.W., Diederichs, K., Welte, W.
Deposit date:1999-07-18
Release date:2000-06-05
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of the Antibiotic Albomycin in Complex with the Outer Membrane Protein Fhua
Protein Sci., 9, 2000
3NGA
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HUMAN CK2 CATALYTIC DOMAIN IN COMPLEX WITH CX-4945
Descriptor:Casein kinase II subunit alpha, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, SULFATE ION
Authors:Ferguson, A.D.
Deposit date:2010-06-11
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural basis of CX-4945 binding to human protein kinase CK2.
Febs Lett., 585, 2011
3NSZ
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HUMAN CK2 CATALYTIC DOMAIN IN COMPLEX WITH AMPPN
Descriptor:Casein kinase II subunit alpha, GLYCEROL, SULFATE ION, ...
Authors:Ferguson, A.D.
Deposit date:2010-07-02
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis of CX-4945 binding to human protein kinase CK2.
Febs Lett., 585, 2011
1KMO
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CRYSTAL STRUCTURE OF THE OUTER MEMBRANE TRANSPORTER FECA
Descriptor:Iron(III) dicitrate transport protein fecA, LAURYL DIMETHYLAMINE-N-OXIDE, HEPTANE-1,2,3-TRIOL
Authors:Ferguson, A.D., Chakraborty, R., Smith, B.S., Esser, L., van der Helm, D., Deisenhofer, J.
Deposit date:2001-12-17
Release date:2002-03-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of gating by the outer membrane transporter FecA.
Science, 295, 2002
1KMP
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CRYSTAL STRUCTURE OF THE OUTER MEMBRANE TRANSPORTER FECA COMPLEXED WITH FERRIC CITRATE
Descriptor:IRON(III) DICITRATE TRANSPORT PROTEIN FECA, FE (III) ION, CITRIC ACID, ...
Authors:Ferguson, A.D., Chakraborty, R., Smith, B.S., Esser, L., van der Helm, D., Deisenhofer, J.
Deposit date:2001-12-17
Release date:2002-03-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of gating by the outer membrane transporter FecA.
Science, 295, 2002
1ZZV
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SOLUTION NMR STRUCTURE OF THE PERIPLASMIC SIGNALING DOMAIN OF THE OUTER MEMBRANE IRON TRANSPORTER FECA FROM ESCHERICHIA COLI.
Descriptor:Iron(III) dicitrate transport protein fecA
Authors:Ferguson, A.D., Amezcua, C.A., Chelliah, Y., Rosen, M.K., Deisenhofer, J.
Deposit date:2005-06-14
Release date:2006-09-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
2A02
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SOLUTION NMR STRUCTURE OF THE PERIPLASMIC SIGNALING DOMAIN OF THE OUTER MEMBRANE IRON TRANSPORTER PUPA FROM PSEUDOMONAS PUTIDA.
Descriptor:Ferric-pseudobactin 358 receptor
Authors:Ferguson, A.D., Amezcua, C.A., Chelliah, Y., Rosen, M.K., Deisenhofer, J.
Deposit date:2005-06-15
Release date:2006-09-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
2A2P
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SOLUTION STRUCTURE OF SELM FROM MUS MUSCULUS
Descriptor:Selenoprotein M
Authors:Ferguson, A.D., Labunskyy, V.M., Fomenko, D.E., Chelliah, Y., Amezcua, C.A., Rizo, J., Gladyshev, V.N., Deisenhofer, J.
Deposit date:2005-06-22
Release date:2005-12-06
Last modified:2014-04-09
Method:SOLUTION NMR
Cite:NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family.
J.Biol.Chem., 281, 2006
2A4H
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SOLUTION STRUCTURE OF SEP15 FROM DROSOPHILA MELANOGASTER
Descriptor:Selenoprotein Sep15
Authors:Ferguson, A.D., Labunskyy, V.M., Fomenko, D.E., Chelliah, Y., Amezcua, C.A., Rizo, J., Gladyshev, V.N., Deisenhofer, J.
Deposit date:2005-06-28
Release date:2005-12-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family.
J.Biol.Chem., 281, 2006
2Q7M
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CRYSTAL STRUCTURE OF HUMAN FLAP WITH MK-591
Descriptor:Arachidonate 5-lipoxygenase-activating protein, 3-[3-(TERT-BUTYLTHIO)-1-(4-CHLOROBENZYL)-5-(QUINOLIN-2-YLMETHOXY)-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC ACID
Authors:Ferguson, A.D.
Deposit date:2007-06-07
Release date:2007-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
Science, 317, 2007
2Q7R
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CRYSTAL STRUCTURE OF HUMAN FLAP WITH AN IODINATED ANALOG OF MK-591
Descriptor:Arachidonate 5-lipoxygenase-activating protein, 3-[3-(3,3-DIMETHYLBUTANOYL)-1-(4-IODOBENZYL)-5-(QUINOLIN-2-YLMETHOXY)-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC ACID
Authors:Ferguson, A.D.
Deposit date:2007-06-07
Release date:2007-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
Science, 317, 2007
3S7B
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STRUCTURAL BASIS OF SUBSTRATE METHYLATION AND INHIBITION OF SMYD2
Descriptor:N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, (R,R)-2,3-BUTANEDIOL, ...
Authors:Ferguson, A.D.
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis of Substrate Methylation and Inhibition of SMYD2.
Structure, 19, 2011
3S7D
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STRUCTURAL BASIS OF SUBSTRATE METHYLATION AND INHIBITION OF SMYD2
Descriptor:N-lysine methyltransferase SMYD2, Monomethylated p53 peptide, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Ferguson, A.D.
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Substrate Methylation and Inhibition of SMYD2.
Structure, 19, 2011
3S7F
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STRUCTURAL BASIS OF SUBSTRATE METHYLATION AND INHIBITION OF SMYD2
Descriptor:N-lysine methyltransferase SMYD2, p53 peptide, S-ADENOSYLMETHIONINE, ...
Authors:Ferguson, A.D.
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Basis of Substrate Methylation and Inhibition of SMYD2.
Structure, 19, 2011
3S7J
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STRUCTURAL BASIS OF SUBSTRATE METHYLATION AND INHIBITION OF SMYD2
Descriptor:N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ZINC ION
Authors:Ferguson, A.D.
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural Basis of Substrate Methylation and Inhibition of SMYD2.
Structure, 19, 2011
5KGD
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CRYSTAL STRUCTURE OF PIM1 WITH INHIBITOR: 2-PYRIDIN-3-YL-1~{H}-BENZIMIDAZOLE
Descriptor:Serine/threonine-protein kinase pim-1, 1,2-ETHANEDIOL, 2-pyridin-3-yl-1~{H}-benzimidazole, ...
Authors:Ferguson, A.D.
Deposit date:2016-06-13
Release date:2017-08-09
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of PIM1 in complex with inhibitor
To Be Published
5KGE
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CRYSTAL STRUCTURE OF PIM1 WITH INHIBITOR: 5-(3,4-DICHLOROPHENYL)-1~{H}-PYRAZOL-3-AMINE
Descriptor:Serine/threonine-protein kinase pim-1, 1,2-ETHANEDIOL, 5-(3,4-dichlorophenyl)-1~{H}-pyrazol-3-amine, ...
Authors:Ferguson, A.D.
Deposit date:2016-06-13
Release date:2017-08-09
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of PIM1 in complex with inhibitor
To Be Published
5KGG
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CRYSTAL STRUCTURE OF PIM1 WITH INHIBITOR: 2-(5-CHLORANYL-1~{H}-INDOL-3-YL)ETHANAMINE
Descriptor:Serine/threonine-protein kinase pim-1, CHLORIDE ION, 1,2-ETHANEDIOL, ...
Authors:Ferguson, A.D.
Deposit date:2016-06-13
Release date:2017-08-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of PIM1 in complex with inhibitor
To Be Published
5KGI
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CRYSTAL STRUCTURE OF PIM1 WITH INHIBITOR 2-[3,4-BIS(CHLORANYL)PHENOXY]ETHANAMINE
Descriptor:Serine/threonine-protein kinase pim-1, 1,2-ETHANEDIOL, 2-[3,4-bis(chloranyl)phenoxy]ethanamine, ...
Authors:Ferguson, A.D.
Deposit date:2016-06-13
Release date:2017-08-09
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structure of PIM1 in complex with inhibitor
To Be Published
5KGK
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CRYSTAL STRUCTURE OF PIM1 WITH INHIBITOR: 3-(4-METHOXYPHENYL)-1~{H}-PYRAZOL-5-AMINE
Descriptor:Serine/threonine-protein kinase pim-1, 1,2-ETHANEDIOL, 3-(4-methoxyphenyl)-1~{H}-pyrazol-5-amine, ...
Authors:Ferguson, A.D.
Deposit date:2016-06-13
Release date:2017-08-09
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structure of PIM1 in complex with inhibitor
To Be Published
5KU8
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CRYSTAL STRUCTURE OF CK2
Descriptor:Casein kinase II subunit alpha, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Ferguson, A.D., Dowling, J.
Deposit date:2016-07-13
Release date:2017-11-08
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of CK2
To Be Published