Author results

2KOX
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NMR RESIDUAL DIPOLAR COUPLINGS IDENTIFY LONG RANGE CORRELATED MOTIONS IN THE BACKBONE OF THE PROTEIN UBIQUITIN
Descriptor:Ubiquitin
Authors:Fenwick, R.B., Richter, B., Lee, D., Walter, K.F.A., Milovanovic, D., Becker, S., Lakomek, N.A., Griesinger, C., Salvatella, X.
Deposit date:2009-10-02
Release date:2011-06-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Weak Long-Range Correlated Motions in a Surface Patch of Ubiquitin Involved in Molecular Recognition
J.Am.Chem.Soc., 2011
2KWH
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RAL BINDING DOMAIN OF RLIP76 (RALBP1)
Descriptor:RalA-binding protein 1
Authors:Fenwick, R.B., Campbell, L.J., Rajasekar, K., Prasannan, S., Nietlispach, D., Camonis, J., Owen, D., Mott, H.R.
Deposit date:2010-04-12
Release date:2010-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction
Structure, 18, 2010
2KWI
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RALB-RLIP76 (RALBP1) COMPLEX
Descriptor:Ras-related protein Ral-B, RalA-binding protein 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Fenwick, R.B., Campbell, L.J., Rajasekar, K., Prasannan, S., Nietlispach, D., Camonis, J., Owen, D., Mott, H.R.
Deposit date:2010-04-12
Release date:2010-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction
Structure, 18, 2010
4NX6
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SINGLE ROOM TEMPERATURE MODEL OF DHFR
Descriptor:Dihydrofolate reductase, FOLIC ACID, BETA-MERCAPTOETHANOL, ...
Authors:Fenwick, R.B., van den Bedem, H., Fraser, J.S., Wright, P.E.
Deposit date:2013-12-08
Release date:2014-01-15
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NX7
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SINGLE CRYOGENIC TEMPERATURE MODEL OF DHFR
Descriptor:Dihydrofolate reductase, MANGANESE (II) ION, FOLIC ACID, ...
Authors:Fenwick, R.B., van den Bedem, H., Fraser, J.S., Wright, P.E.
Deposit date:2013-12-08
Release date:2014-01-15
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.
Proc.Natl.Acad.Sci.USA, 111, 2014
2KE5
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SOLUTION STRUCTURE AND DYNAMICS OF THE SMALL GTPASE RALB IN ITS ACTIVE CONFORMATION: SIGNIFICANCE FOR EFFECTOR PROTEIN BINDING
Descriptor:Ras-related protein Ral-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION
Authors:Fenwick, R., Prasannan, S., Campbell, L.J., Nietlispach, D., Evetts, K.A., Camonis, J., Mott, H.R., Owen, D.
Deposit date:2009-01-23
Release date:2009-02-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding
Biochemistry, 48, 2009
5CC9
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L28F E.COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND OXIDIZED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE
Descriptor:Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5,10-DIDEAZATETRAHYDROFOLIC ACID
Authors:Oyen, D., Wright, P.E.
Deposit date:2015-07-01
Release date:2015-08-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
5CCC
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WILD-TYPE E.COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND OXIDIZED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE
Descriptor:Dihydrofolate reductase, 5,10-DIDEAZATETRAHYDROFOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Oyen, D., Wright, P.E.
Deposit date:2015-07-01
Release date:2015-08-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
5W3Q
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L28F E.COLI DHFR IN COMPLEX WITH NADPH
Descriptor:Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION
Authors:Oyen, D., Wright, P.E., Wilson, I.A.
Deposit date:2017-06-08
Release date:2017-08-09
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion.
J. Am. Chem. Soc., 139, 2017