2A8Z
 
 | | Structure Of A Cold-Adapted Family 8 Xylanase | | Descriptor: | endo-1,4-beta-xylanase | | Authors: | Collins, T, De Vos, D, Hoyoux, A, Savvides, S.N, Gerday, C, Van Beeumen, J, Feller, G. | | Deposit date: | 2005-07-10 | | Release date: | 2005-12-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Study of the active site residues of a glycoside hydrolase family 8 xylanase.
J.Mol.Biol., 354, 2005
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2B4F
 | | Structure Of A Cold-Adapted Family 8 Xylanase in complex with substrate | | Descriptor: | beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, endo-1,4-beta-xylanase | | Authors: | De Vos, D, Collins, T, Savvides, S.N, Feller, G, Van Beeumen, J.J. | | Deposit date: | 2005-09-23 | | Release date: | 2006-09-05 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Oligosaccharide binding in family 8 glycosidases: crystal structures of active-site mutants of the beta-1,4-xylanase pXyl from Pseudoaltermonas haloplanktis TAH3a in complex with substrate and product.
Biochemistry, 45, 2006
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1H14
 | | Structure of a cold-adapted family 8 xylanase | | Descriptor: | ENDO-1,4-BETA-XYLANASE | | Authors: | Van Petegem, F, Collins, T, Meuwis, M.A, Feller, G, Gerday, C, Van Beeumen, J. | | Deposit date: | 2002-07-02 | | Release date: | 2003-03-13 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Structure of a Cold-Adapted Family 8 Xylanase at 1.3 A Resolution: Structural Adaptations to Cold and Investigation of the Active Site
J.Biol.Chem., 278, 2003
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2W5W
 | | Structure of TAB5 alkaline phosphatase mutant His 135 Asp with Zn bound in the M3 site. | | Descriptor: | ALKALINE PHOSPHATASE, ZINC ION | | Authors: | Koutsioulis, D, Lyskowski, A, Maki, S, Guthrie, E, Feller, G, Bouriotis, V, Heikinheimo, P. | | Deposit date: | 2008-12-15 | | Release date: | 2009-11-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Coordination Sphere of the Third Metal Site is Essential to the Activity and Metal Selectivity of Alkaline Phosphatases.
Protein Sci., 19, 2010
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2W5X
 | | Structure of TAB5 alkaline phosphatase mutant His 135 Glu with Mg bound in the M3 site. | | Descriptor: | ALKALINE PHOSPHATASE, MAGNESIUM ION, ZINC ION | | Authors: | Koutsioulis, D, Lyskowski, A, Maki, S, Guthrie, E, Feller, G, Bouriotis, V, Heikinheimo, P. | | Deposit date: | 2008-12-15 | | Release date: | 2009-11-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Coordination Sphere of the Third Metal Site is Essential to the Activity and Metal Selectivity of Alkaline Phosphatases.
Protein Sci., 19, 2010
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2W5V
 | | Structure of TAB5 alkaline phosphatase mutant His 135 Asp with Mg bound in the M3 site. | | Descriptor: | ALKALINE PHOSPHATASE, MAGNESIUM ION, ZINC ION | | Authors: | Koutsioulis, D, Lyskowski, A, Maki, S, Guthrie, E, Feller, G, Bouriotis, V, Heikinheimo, P. | | Deposit date: | 2008-12-15 | | Release date: | 2009-11-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Coordination Sphere of the Third Metal Site is Essential to the Activity and Metal Selectivity of Alkaline Phosphatases.
Protein Sci., 19, 2010
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1H12
 | | Structure of a cold-adapted family 8 xylanase | | Descriptor: | ENDO-1,4-BETA-XYLANASE, alpha-D-xylopyranose, beta-D-xylopyranose | | Authors: | Van Petegem, F, Collins, T, Meuwis, M.A, Feller, G, Gerday, C, Van Beeumen, J. | | Deposit date: | 2002-07-02 | | Release date: | 2003-03-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The Structure of a Cold-Adapted Family 8 Xylanase at 1.3 A Resolution: Structural Adaptations to Cold and Investigation of the Active Site
J.Biol.Chem., 278, 2003
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1H13
 | | Structure of a cold-adapted family 8 xylanase | | Descriptor: | ENDO-1,4-BETA-XYLANASE | | Authors: | Van Petegem, F, Collins, T, Meuwis, M.A, Feller, G, Gerday, C, Van Beeumen, J. | | Deposit date: | 2002-07-02 | | Release date: | 2003-03-13 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The Structure of a Cold-Adapted Family 8 Xylanase at 1.3 A Resolution: Structural Adaptations to Cold and Investigation of the Active Site
J.Biol.Chem., 278, 2003
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1XWQ
 | | Structure Of A Cold-Adapted Family 8 Xylanase | | Descriptor: | beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, endo-1,4-beta-xylanase | | Authors: | De Vos, D, Collins, T, Hoyoux, A, Savvides, S.N, Gerday, C, Van Beeumen, J.J, Feller, G. | | Deposit date: | 2004-11-02 | | Release date: | 2005-10-11 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Study of the active site residues of a glycoside hydrolase family 8 xylanase
J.Mol.Biol., 354, 2005
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1XWT
 | | Structure Of A Cold-Adapted Family 8 Xylanase | | Descriptor: | endo-1,4-beta-xylanase | | Authors: | De Vos, D, Collins, T, Hoyoux, A, Savvides, S.N, Gerday, C, Van Beeumen, J.J, Feller, G. | | Deposit date: | 2004-11-02 | | Release date: | 2005-10-11 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Study of the active site residues of a glycoside hydrolase family 8 xylanase
J.Mol.Biol., 354, 2005
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1XW2
 | | Structure Of A Cold-Adapted Family 8 Xylanase | | Descriptor: | Endo-1,4-beta-Xylanase | | Authors: | Collins, T, De Vos, D, Hoyoux, A, Savvides, S.N, Gerday, C, Van Beeumen, J, Feller, G. | | Deposit date: | 2004-10-29 | | Release date: | 2005-10-11 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Study of the active site residues of a glycoside hydrolase family 8 xylanase
J.Mol.Biol., 354, 2005
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1AQM
 | | ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS COMPLEXED WITH TRIS | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALPHA-AMYLASE, CALCIUM ION, ... | | Authors: | Aghajari, N, Haser, R. | | Deposit date: | 1997-07-31 | | Release date: | 1999-03-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.
Protein Sci., 7, 1998
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1AQH
 | | ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS | | Descriptor: | ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION | | Authors: | Aghajari, N, Haser, R. | | Deposit date: | 1997-07-30 | | Release date: | 1999-02-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.
Protein Sci., 7, 1998
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1B0I
 | | ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS | | Descriptor: | CALCIUM ION, CHLORIDE ION, PROTEIN (ALPHA-AMYLASE) | | Authors: | Aghajari, N, Haser, R. | | Deposit date: | 1998-11-10 | | Release date: | 1999-11-17 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of the psychrophilic Alteromonas haloplanctis alpha-amylase give insights into cold adaptation at a molecular level.
Structure, 6, 1998
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6YRP
 | | Crystal Structure of the VIM-2 Acquired Metallo-beta-Lactamase in Complex with JMV-4690 (Cpd 31) | | Descriptor: | 1,2-ETHANEDIOL, 2-[[[3-(5-methoxy-2-oxidanyl-phenyl)-5-sulfanylidene-1~{H}-1,2,4-triazol-4-yl]amino]methyl]benzoic acid, ACETATE ION, ... | | Authors: | Docquier, J.D, Pozzi, C, De Luca, F, Benvenuti, M, Mangani, S. | | Deposit date: | 2020-04-20 | | Release date: | 2020-09-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 208, 2020
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7PP0
 | | Crystal structure of the VIM-2 acquired metallo-beta-Lactamase in complex with compound 28 (JMV-7038) | | Descriptor: | 2-[2-[3-[3-(2-morpholin-4-ylethoxy)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]ethyl]benzoic acid, ACETATE ION, Metallo-beta-lactamase VIM-2-like protein, ... | | Authors: | Tassone, G, Benvenuti, M, Verdirosa, F, Corsica, G, Chelini, G, De Luca, F, Docquier, J.D, Pozzi, C, Mangani, S. | | Deposit date: | 2021-09-10 | | Release date: | 2022-03-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | 1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-beta-Lactamase Inhibitors.
Chemmedchem, 17, 2022
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6HXE
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6I06
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8A4M
 | | Crystal structure of the VIM-2 acquired metallo-beta-Lactamase in complex with compound 8 (JMV-7061) | | Descriptor: | (2~{S})-2-[bis(1~{H}-imidazol-4-ylmethyl)amino]-5-(3-phenyl-5-sulfanylidene-1~{H}-1,2,4-triazol-4-yl)pentanoic acid, ACETATE ION, Metallo-beta-lactamase VIM-2-like protein, ... | | Authors: | Tassone, G, Benvenuti, M, Verdirosa, F, Corsica, G, Sannio, F, Docquier, J.D, Pozzi, C, Mangani, S. | | Deposit date: | 2022-06-13 | | Release date: | 2023-04-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-beta-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.
J.Med.Chem., 65, 2022
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8A76
 | | Metallo-beta-lactamase NDM-1 in complex with 1,2,4-Triazole-3-thione compound 26 | | Descriptor: | (2~{S})-2-[bis(pyridin-2-ylmethyl)amino]-5-(3-phenyl-5-sulfanylidene-1~{H}-1,2,4-triazol-4-yl)pentanoic acid, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Vascon, F, Legru, A, Hernandez, J.F, Cendron, L. | | Deposit date: | 2022-06-20 | | Release date: | 2022-12-14 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-beta-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.
J.Med.Chem., 65, 2022
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1JD9
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1JD7
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3CIA
 | | Crystal structure of cold-aminopeptidase from Colwellia psychrerythraea | | Descriptor: | ZINC ION, cold-active aminopeptidase | | Authors: | Bauvois, C, Jacquamet, L, Borel, F, Ferrer, J.-L. | | Deposit date: | 2008-03-11 | | Release date: | 2008-07-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of the Cold-active Aminopeptidase from Colwellia psychrerythraea, a Close Structural Homologue of the Human Bifunctional Leukotriene A4 Hydrolase.
J.Biol.Chem., 283, 2008
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1TVP
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1TVN
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