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1AJJ
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BU of 1ajj by Molmil
LDL RECEPTOR LIGAND-BINDING MODULE 5, CALCIUM-COORDINATING
Descriptor: CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, SULFATE ION
Authors:Fass, D, Blacklow, S.C, Kim, P.S, Berger, J.M.
Deposit date:1997-05-04
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module.
Nature, 388, 1997
1B79
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BU of 1b79 by Molmil
N-TERMINAL DOMAIN OF DNA REPLICATION PROTEIN DNAB
Descriptor: DnaB Helicase
Authors:Fass, D, Bogden, C.E, Berger, J.M.
Deposit date:1999-01-28
Release date:1999-06-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the N-terminal domain of the DnaB hexameric helicase.
Structure Fold.Des., 7, 1999
1AOL
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BU of 1aol by Molmil
FRIEND MURINE LEUKEMIA VIRUS RECEPTOR-BINDING DOMAIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GP70, ZINC ION
Authors:Fass, D, Davey, R.A, Hamson, C.A, Kim, P.S, Cunningham, J.M, Berger, J.M.
Deposit date:1997-07-08
Release date:1997-10-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution.
Science, 277, 1997
1BJT
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BU of 1bjt by Molmil
TOPOISOMERASE II RESIDUES 409-1201
Descriptor: TOPOISOMERASE II
Authors:Fass, D, Bogden, C.E, Berger, J.M.
Deposit date:1998-06-29
Release date:1999-05-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands.
Nat.Struct.Biol., 6, 1999
1MOF
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BU of 1mof by Molmil
COAT PROTEIN
Descriptor: CHLORIDE ION, MOLONEY MURINE LEUKEMIA VIRUS P15
Authors:Fass, D, Harrison, S.C, Kim, P.S.
Deposit date:1996-04-02
Release date:1996-10-14
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Retrovirus envelope domain at 1.7 angstrom resolution.
Nat.Struct.Biol., 3, 1996
4TW5
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BU of 4tw5 by Molmil
Structure Of the First Two Thioredoxin Domains of Saccharomyces cerevisiae Eps1p
Descriptor: Eps1p
Authors:Fass, D, Biran, S.
Deposit date:2014-06-30
Release date:2014-12-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:The eps1p protein disulfide isomerase conserves classic thioredoxin superfamily amino Acid motifs but not their functional geometries.
Plos One, 9, 2014
1A8V
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BU of 1a8v by Molmil
STRUCTURE OF THE RNA-BINDING DOMAIN OF THE RHO TRANSCRIPTION TERMINATOR
Descriptor: COPPER (II) ION, TRANSCRIPTION TERMINATION FACTOR RHO
Authors:Fass, D, Bogden, C, Berger, J.M.
Deposit date:1998-03-28
Release date:1999-05-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis for terminator recognition by the Rho transcription termination factor.
Mol.Cell, 3, 1999
4IJ3
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BU of 4ij3 by Molmil
Oxidoreductase Fragment of Human QSOX1 in Complex with a FAB Fragment from an Anti- Human QSOX1 Antibody
Descriptor: Heavy chain of FAB fragment, Light chain of FAB fragment, PHOSPHATE ION, ...
Authors:Fass, D, Grossman, I.
Deposit date:2012-12-21
Release date:2013-11-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An Inhibitory Antibody Blocks the First Step in the Dithiol/Disulfide Relay Mechanism of the Enzyme QSOX1.
J.Mol.Biol., 425, 2013
5D96
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BU of 5d96 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1
Descriptor: Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Sulfhydryl oxidase 1
Authors:Fass, D, Grossman, I.
Deposit date:2015-08-18
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
3T58
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BU of 3t58 by Molmil
C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
Authors:Fass, D, Alon, A, Gat, Y.
Deposit date:2011-07-27
Release date:2012-05-30
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
3T59
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BU of 3t59 by Molmil
C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
Authors:Fass, D, Alon, A, Gat, Y.
Deposit date:2011-07-27
Release date:2012-05-30
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
3Q6O
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BU of 3q6o by Molmil
Oxidoreductase Fragment of Human QSOX1
Descriptor: SULFATE ION, Sulfhydryl oxidase 1
Authors:Fass, D, Alon, A.
Deposit date:2011-01-03
Release date:2012-05-30
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
2I1A
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BU of 2i1a by Molmil
A Retroviral Protease-Like Domain in the Eukaryotic Protein Ddi1
Descriptor: DNA damage-inducible protein DDI1
Authors:Fass, D, Sirkis, R.
Deposit date:2006-08-14
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ddi1, a eukaryotic protein with the retroviral protease fold.
J.Mol.Biol., 364, 2006
3NVJ
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BU of 3nvj by Molmil
Crystal structure of the C143A/C166A mutant of Ero1p
Descriptor: 1-ETHYL-PYRROLIDINE-2,5-DIONE, CADMIUM ION, Endoplasmic oxidoreductin-1, ...
Authors:Fass, D, Vonshak, O.
Deposit date:2010-07-08
Release date:2010-11-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Steps in reductive activation of the disulfide-generating enzyme Ero1p
Protein Sci., 19, 2010
8QCI
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BU of 8qci by Molmil
FCGBP D10 Assembly Segment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Yeshaya, N, Fass, D.
Deposit date:2023-08-27
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Protein Sci., 33, 2024
7ZWH
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BU of 7zwh by Molmil
VWF Tubules of D1D2 and D'D3A1 domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Javitt, G, Fass, D.
Deposit date:2022-05-19
Release date:2022-07-13
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Assembly of von Willebrand factor tubules with in vivo helical parameters requires A1 domain insertion.
Blood, 140, 2022
8OV0
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BU of 8ov0 by Molmil
MUC5AC CysD7 amino acids 3518-3626
Descriptor: CALCIUM ION, CHLORIDE ION, Mucin-5AC
Authors:Khmelnitsky, L, Milo, A, Dym, O, Fass, D.
Deposit date:2023-04-25
Release date:2023-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Diversity of CysD domains in gel-forming mucins.
Febs J., 290, 2023
8OER
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BU of 8oer by Molmil
MUC5B amino acids 26-1435
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-5B
Authors:Khmelnitsky, L, Fass, D.
Deposit date:2023-03-12
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Pulmonary Fibrosis Linked to Impaired Mucin 5B Supramolecular Assembly
To Be Published
8OES
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BU of 8oes by Molmil
MUC5B amino acids 26-1435 Three beads
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-5B
Authors:Khmelnitsky, L, Fass, D.
Deposit date:2023-03-12
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Pulmonary Fibrosis Linked to Impaired Mucin 5B Supramolecular Assembly
To Be Published
8AON
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BU of 8aon by Molmil
Oxidoreductase fragment of human QSOX1 in complex with a Fab fragment of a humanized anti-QSOX1 antibody
Descriptor: GLYCEROL, Heavy chain, Light chain, ...
Authors:Khmelnitsky, L, Fass, D.
Deposit date:2022-08-08
Release date:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Reliable energy-based antibody humanization and stabilization
To Be Published
8CK2
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BU of 8ck2 by Molmil
MUC2 CysD1 G1352S
Descriptor: ACETATE ION, CALCIUM ION, Mucin-2, ...
Authors:Khmelnitsky, L, Fass, D.
Deposit date:2023-02-14
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Pulmonary Fibrosis Mutation Undermines Mucin 5B Supramolecular Assembly
To Be Published
3ED3
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BU of 3ed3 by Molmil
Crystal Structure of the Yeast Dithiol/Disulfide Oxidoreductase Mpd1p
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Protein disulfide-isomerase MPD1
Authors:Vitu, E, Greenblatt, H.M, Fass, D.
Deposit date:2008-09-02
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Yeast Mpd1p reveals the structural diversity of the protein disulfide isomerase family
J.Mol.Biol., 384, 2008
6HF1
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BU of 6hf1 by Molmil
Mutant oxidoreductase fragment of mouse QSOX1 in complex with an antibody Fab
Descriptor: Fab 316 heavy chain, Fab 316 light chain, Sulfhydryl oxidase 1
Authors:Grossman-Haham, I, Fass, D.
Deposit date:2018-08-21
Release date:2019-04-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures.
Protein Sci., 28, 2019
6GC2
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BU of 6gc2 by Molmil
AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface
Descriptor: Heavy chain, Light Chain
Authors:Warszawski, S, Katz, A, Khmelnitsky, L, Ben Nissan, G, Javitt, G, Dym, O, Unger, T, Knop, O, Diskin, R, Albeck, S, Fass, D, Sharon, M, Fleishman, S.J.
Deposit date:2018-04-17
Release date:2019-05-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
Plos Comput.Biol., 15, 2019
2A8V
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BU of 2a8v by Molmil
RHO TRANSCRIPTION TERMINATION FACTOR/RNA COMPLEX
Descriptor: 5'-R(P*CP*CP*C)-3', 5'-R(P*CP*CP*CP*CP*CP*C)-3', RNA BINDING DOMAIN OF RHO TRANSCRIPTION TERMINATION FACTOR
Authors:Bogden, C.E, Fass, D, Bergman, N, Nichols, M.D, Berger, J.M.
Deposit date:1998-11-08
Release date:1999-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structural basis for terminator recognition by the Rho transcription termination factor.
Mol.Cell, 3, 1999

 

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