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1WP5
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BU of 1wp5 by Molmil
Crystal structure of the C-terminal domain of DNA topoisomerase IV
Descriptor: topoisomerase IV
Authors:Hsieh, T.-J, Farh, L, Huang, W.M, Chan, N.-L.
Deposit date:2004-08-30
Release date:2004-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure of the topoisomerase IV C-terminal domain: a broken beta-propeller implies a role as geometry facilitator in catalysis
J.Biol.Chem., 279, 2004
3L6V
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BU of 3l6v by Molmil
Crystal Structure of the Xanthomonas campestris Gyrase A C-terminal Domain
Descriptor: DNA gyrase subunit A
Authors:Hsieh, T.J, Yen, T.J, Lin, T.S, Chang, H.T, Huang, S.Y, Farh, L, Chan, N.L.
Deposit date:2009-12-26
Release date:2010-03-09
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Twisting of the DNA binding surface by a beta-strand-bearing proline modulates DNA gyrase activity
To be Published
3QX3
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BU of 3qx3 by Molmil
Human topoisomerase IIbeta in complex with DNA and etoposide
Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wu, C.C, Li, T.K, Farh, L, Lin, L.Y, Lin, T.S, Yu, Y.J, Yen, T.J, Chiang, C.W, Chan, N.L.
Deposit date:2011-03-01
Release date:2011-07-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.162 Å)
Cite:Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide
Science, 333, 2011

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