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5E5A
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CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE
分子名称:DNA (146-MER), Histone H3.2, Histone H4, ...
著者Fang, Q., Chen, P., Wang, M., Fang, J., Yang, N., Li, G., Xu, R.M.
登録日2015-10-08
公開日2016-02-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.809 Å)
主引用文献Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
6NCL
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NEAR-ATOMIC STRUCTURE OF ICOSAHEDRALLY AVERAGED PBCV-1 CAPSID
分子名称:P14, P9, P10, ...
著者Fang, Q., Rossmann, M.G.
登録日2018-12-11
公開日2019-01-30
最終更新日2019-02-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Near-atomic structure of a giant virus.
Nat Commun, 10, 2019
6NQD
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CRYO-EM STRUCTURE OF T/F100 SOSIP.664 HIV-1 ENV TRIMER IN COMPLEX WITH 8ANC195 FAB
分子名称:T/F100 Env gp120, T/F100 Env gp41, 8ANC195 G52K5 heavy chain, ...
著者Fang, Q., Rossmann, M.G.
登録日2019-01-21
公開日2019-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer.
Nat Commun, 10, 2019
5ZVS
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STRUCTURE OF RNA POLYMERASE COMPLEX AND GENOME WITHIN A DSRNA VIRUS PROVIDES INSIGHTS INTO THE MECHANISMS OF TRANSCRIPTION AND ASSEMBLY
分子名称:VP3, VP2, Putative core protein NTPase/VP5
著者Liu, H., Fang, Q., Cheng, L.
登録日2018-05-12
公開日2018-07-04
最終更新日2018-07-25
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZVT
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STRUCTURE OF RNA POLYMERASE COMPLEX AND GENOME WITHIN A DSRNA VIRUS PROVIDES INSIGHTS INTO THE MECHANISMS OF TRANSCRIPTION AND ASSEMBLY
分子名称:Outer capsid VP7, N-terminus of outer capsid protein VP5, C-terminus of outer capsid protein VP5, ...
著者Liu, H., Fang, Q., Cheng, L.
登録日2018-05-12
公開日2018-07-04
最終更新日2018-07-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3EP3
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HUMAN ADOMETDC D174N MUTANT WITH NO PUTRESCINE BOUND
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP4
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HUMAN ADOMETDC E256Q MUTANT WITH NO PUTRESCINE BOUND
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP5
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HUMAN ADOMETDC E178Q MUTANT WITH NO PUTRESCINE BOUND
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP6
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HUMAN ADOMETDC D174N MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP7
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HUMAN ADOMETDC E256Q MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP8
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HUMAN ADOMETDC E178Q MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP9
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HUMAN ADOMETDC WITH NO PUTRESCINE BOUND
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EPA
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HUMAN ADOMETDC E178Q MUTANT COMPLEXED WITH PUTRESCINE
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EPB
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HUMAN ADOMETDC E256Q MUTANT COMPLEXED WITH PUTRESCINE
分子名称:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, 1,4-DIAMINOBUTANE, ...
著者Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3IYL
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ATOMIC CRYOEM STRUCTURE OF A NONENVELOPED VIRUS SUGGESTS HOW MEMBRANE PENETRATION PROTEIN IS PRIMED FOR CELL ENTRY
分子名称:Outer capsid VP4, Core protein VP6, VP1, ...
著者Zhang, X., Jin, L., Fang, Q., Hui, W., Zhou, Z.H.
登録日2010-02-02
公開日2010-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry.
Cell(Cambridge,Mass.), 141, 2010
3K1Q
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BACKBONE MODEL OF AN AQUAREOVIRUS VIRION BY CRYO-ELECTRON MICROSCOPY AND BIOINFORMATICS
分子名称:VP1, VP3A, VP3B, ...
著者Cheng, L.P., Zhu, J., Hiu, W.H., Zhang, X.K., Honig, B., Fang, Q., Zhou, Z.H.
登録日2009-09-28
公開日2010-03-23
最終更新日2015-01-14
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Backbone Model of an Aquareovirus Virion by Cryo-Electron Microscopy and Bioinformatics
J.Mol.Biol., 397, 2010
4KUD
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED SIR3 BAH DOMAIN D205N MUTANT IN COMPLEX WITH YEAST NUCLEOSOME CORE PARTICLE
分子名称:Histone H3, Histone H4, Histone H2A.2, ...
著者Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
登録日2013-05-22
公開日2013-08-07
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
4KUI
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED YEAST SIR3 BAH DOMAIN
分子名称:Regulatory protein SIR3, ISOPROPYL ALCOHOL, ACETIC ACID
著者Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
登録日2013-05-22
公開日2013-08-07
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
4KUL
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED YEAST SIR3 BAH DOMAIN V83P MUTANT
分子名称:Regulatory protein SIR3
著者Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
登録日2013-05-22
公開日2013-08-07
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
4PH4
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THE CRYSTAL STRUCTURE OF HUMAN VPS34 IN COMPLEX WITH PIK-III
分子名称:Phosphatidylinositol 3-kinase catalytic subunit type 3, GLYCEROL, 4'-(cyclopropylmethyl)-N~2~-(pyridin-4-yl)-4,5'-bipyrimidine-2,2'-diamine
著者Knapp, M.S., Elling, R.A.
登録日2014-05-04
公開日2014-10-29
最終更新日2015-02-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Nat.Cell Biol., 16, 2014
4PSW
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CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX
分子名称:Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4 type VIII, ...
著者Yang, M., Li, Y.
登録日2014-03-08
公開日2014-07-09
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
4PSX
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CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX
分子名称:Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4, ...
著者Yang, M., Li, Y.
登録日2014-03-08
公開日2014-07-09
実験手法X-RAY DIFFRACTION (2.509 Å)
主引用文献Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014