Author results

5IAY
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NMR STRUCTURE OF UHRF1 TANDEM TUDOR DOMAINS IN A COMPLEX WITH SPACER PEPTIDE
分子名称:E3 ubiquitin-protein ligase UHRF1, Spacer
著者Fang, J., Cheng, J., Wang, J., Zhang, Q., Liu, M., Gong, R., Wang, P., Zhang, X., Feng, Y., Lan, W., Gong, Z., Tang, C., Wong, J., Yang, H., Cao, C., Xu, Y.
登録日2016-02-22
公開日2016-04-20
実験手法SOLUTION NMR
主引用文献Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition
Nat Commun, 7, 2016
6ADW
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS3 HELICASE (APO FORM)
分子名称:Serine protease NS3, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Fang, J., Lu, G., Gong, P.
登録日2018-08-02
公開日2019-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
ACS Infect Dis, 5, 2019
6ADX
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS3 HELICASE (ADP-MN2+ COMPLEX, FORM 1)
分子名称:Serine protease NS3, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION
著者Fang, J., Lu, G., Gong, P.
登録日2018-08-02
公開日2019-03-13
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Crystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
ACS Infect Dis, 5, 2019
6ADY
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS3 HELICASE (ADP-MN2+ COMPLEX, FORM 2)
分子名称:Serine protease NS3, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION
著者Fang, J., Lu, G., Gong, P.
登録日2018-08-02
公開日2019-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
ACS Infect Dis, 5, 2019
4GU1
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CRYSTAL STRUCTURE OF LSD2
分子名称:Lysine-specific histone demethylase 1B, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ...
著者Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.939 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUR
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3 IN SPACE GROUP P21
分子名称:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3.3, ...
著者Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUS
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3 IN SPACE GROUP P3221
分子名称:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3.3, ...
著者Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUT
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CRYSTAL STRUCTURE OF LSD2-NPAC
分子名称:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
5E5A
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CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE
分子名称:DNA (146-MER), Histone H3.2, Histone H4, ...
著者Fang, Q., Chen, P., Wang, M., Fang, J., Yang, N., Li, G., Xu, R.M.
登録日2015-10-08
公開日2016-02-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.809 Å)
主引用文献Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
4GUU
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH TRANYLCYPROMINE
分子名称:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(3R,3aS,7aR)-10,11-dimethyl-1,4,6-trioxo-3-phenyl-2,3,5,6,7,7a-hexahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate, ...
著者Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GU0
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CRYSTAL STRUCTURE OF LSD2 WITH H3
分子名称:Lysine-specific histone demethylase 1B, Histone H3.3, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Chen, F., Yang, H., Dong, Z., Fang, J., Zhu, T., Gong, W., Xu, Y.
登録日2012-08-29
公開日2013-02-13
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (3.103 Å)
主引用文献Structural insight into substrate recognition by histone demethylase LSD2/KDM1b
Cell Res., 23, 2013
4HSU
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3(1-26)IN SPACE GROUP P21
分子名称:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3, ...
著者Chen, F., Dong, Z., Fang, J., Xu, Y.
登録日2012-10-30
公開日2013-02-13
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (1.988 Å)
主引用文献Structural insight into substrate recognition by histone demethylase LSD2/KDM1b.
Cell Res., 23, 2013
4GY5
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CRYSTAL STRUCTURE OF THE TANDEM TUDOR DOMAIN AND PLANT HOMEODOMAIN OF UHRF1 WITH HISTONE H3K9ME3
分子名称:E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION
著者Cheng, J., Yang, Y., Fang, J., Xiao, J., Zhu, T., Chen, F., Wang, P., Xu, Y.
登録日2012-09-05
公開日2012-11-14
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.956 Å)
主引用文献Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
6MZC
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HUMAN TFIID BC CORE
分子名称:Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 4, Transcription initiation factor TFIID subunit 5, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZD
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HUMAN TFIID LOBE A CANONICAL
分子名称:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 3, Transcription initiation factor TFIID subunit 4, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZL
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HUMAN TFIID CANONICAL STATE
分子名称:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 3, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (23 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZM
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HUMAN TFIID BOUND TO PROMOTER DNA AND TFIIA
分子名称:Transcription initiation factor TFIID subunit 1, TAF1, Transcription initiation factor TFIID subunit 2, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
1L1F
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STRUCTURE OF HUMAN GLUTAMATE DEHYDROGENASE-APO FORM
分子名称:Glutamate Dehydrogenase 1
著者Smith, T.J., Schmidt, T., Fang, J., Wu, J., Siuzdak, G., Stanley, C.A.
登録日2002-02-15
公開日2002-03-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of apo human glutamate dehydrogenase details subunit communication and allostery.
J.Mol.Biol., 318, 2002
3J1Z
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INWARD-FACING CONFORMATION OF THE ZINC TRANSPORTER YIIP REVEALED BY CRYO-ELECTRON MICROSCOPY
分子名称:Cation efflux family protein
著者Coudray, N., Valvo, S., Hu, M., Lasala, R., Kim, C., Vink, M., Zhou, M., Provasi, D., Filizola, M., Tao, J., Fang, J., Penczek, P.A., Ubarretxena-Belandia, I., Stokes, D.L., Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS)
登録日2012-07-24
公開日2012-10-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 110, 2013
3R45
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STRUCTURE OF A CENP-A-HISTONE H4 HETERODIMER IN COMPLEX WITH CHAPERONE HJURP
分子名称:Histone H3-like centromeric protein A, Histone H4, Holliday junction recognition protein, ...
著者Hu, H., Liu, Y., Wang, M., Fang, J., Huang, H., Yang, N., Li, Y., Wang, J., Yao, X., Shi, Y., Li, G., Xu, R.M.
登録日2011-03-17
公開日2011-04-06
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP
Genes Dev., 25, 2011
4YOC
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CRYSTAL STRUCTURE OF HUMAN DNMT1 AND USP7/HAUSP COMPLEX
分子名称:DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION
著者Cheng, J., Yang, H., Fang, J., Gong, R., Wang, P., Li, Z., Xu, Y.
登録日2015-03-11
公開日2015-05-27
実験手法X-RAY DIFFRACTION (2.916 Å)
主引用文献Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.
Nat Commun, 6, 2015
5C56
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CRYSTAL STRUCTURE OF USP7/HAUSP IN COMPLEX WITH ICP0
分子名称:Ubiquitin E3 ligase ICP0, Ubiquitin carboxyl-terminal hydrolase 7
著者Cheng, J., Li, Z., Gong, R., Fang, J., Yang, Y., Sun, C., Yang, H., Xu, Y.
登録日2015-06-19
公開日2015-07-08
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (2.685 Å)
主引用文献Molecular mechanism for the substrate recognition of USP7.
Protein Cell, 6, 2015
1HWY
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BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE
分子名称:GLUTAMATE DEHYDROGENASE, PHOSPHATE ION, 2-OXOGLUTARIC ACID, ...
著者Smith, T.J., Peterson, P.E., Schmidt, T., Fang, J., Stanley, C.A.
登録日2001-01-10
公開日2001-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
J.Mol.Biol., 307, 2001
1NQT
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CRYSTAL STRUCTURE OF BOVINE GLUTAMATE DEHYDROGENASE-ADP COMPLEX
分子名称:Glutamate dehydrogenase 1, ADENOSINE-5'-DIPHOSPHATE
著者Banerjee, S., Schmidt, T., Fang, J., Stanley, C.A., Smith, T.J.
登録日2003-01-23
公開日2003-05-06
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation
Biochemistry, 42, 2003
1NR1
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CRYSTAL STRUCTURE OF THE R463A MUTANT OF HUMAN GLUTAMATE DEHYDROGENASE
分子名称:Glutamate dehydrogenase 1
著者Banerjee, S., Schmidt, T., Fang, J., Stanley, C.A., Smith, T.J.
登録日2003-01-23
公開日2003-05-06
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation
Biochemistry, 42, 2003