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5IAY
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NMR STRUCTURE OF UHRF1 TANDEM TUDOR DOMAINS IN A COMPLEX WITH SPACER PEPTIDE
Descriptor:E3 ubiquitin-protein ligase UHRF1, Spacer
Authors:Fang, J., Cheng, J., Wang, J., Zhang, Q., Liu, M., Gong, R., Wang, P., Zhang, X., Feng, Y., Lan, W., Gong, Z., Tang, C., Wong, J., Yang, H., Cao, C., Xu, Y.
Deposit date:2016-02-22
Release date:2016-04-20
Method:SOLUTION NMR
Cite:Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition
Nat Commun, 7, 2016
6ADW
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS3 HELICASE (APO FORM)
Descriptor:Serine protease NS3, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Fang, J., Lu, G., Gong, P.
Deposit date:2018-08-02
Release date:2019-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
ACS Infect Dis, 5, 2019
6ADX
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS3 HELICASE (ADP-MN2+ COMPLEX, FORM 1)
Descriptor:Serine protease NS3, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION
Authors:Fang, J., Lu, G., Gong, P.
Deposit date:2018-08-02
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Crystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
ACS Infect Dis, 5, 2019
6ADY
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CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS3 HELICASE (ADP-MN2+ COMPLEX, FORM 2)
Descriptor:Serine protease NS3, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION
Authors:Fang, J., Lu, G., Gong, P.
Deposit date:2018-08-02
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
ACS Infect Dis, 5, 2019
4GU1
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CRYSTAL STRUCTURE OF LSD2
Descriptor:Lysine-specific histone demethylase 1B, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.939 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUR
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3 IN SPACE GROUP P21
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3.3, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUS
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3 IN SPACE GROUP P3221
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3.3, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUT
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CRYSTAL STRUCTURE OF LSD2-NPAC
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
5E5A
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CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE
Descriptor:DNA (146-MER), Histone H3.2, Histone H4, ...
Authors:Fang, Q., Chen, P., Wang, M., Fang, J., Yang, N., Li, G., Xu, R.M.
Deposit date:2015-10-08
Release date:2016-02-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.809 Å)
Cite:Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
4GU0
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CRYSTAL STRUCTURE OF LSD2 WITH H3
Descriptor:Lysine-specific histone demethylase 1B, Histone H3.3, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Chen, F., Yang, H., Dong, Z., Fang, J., Zhu, T., Gong, W., Xu, Y.
Deposit date:2012-08-29
Release date:2013-02-13
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (3.103 Å)
Cite:Structural insight into substrate recognition by histone demethylase LSD2/KDM1b
Cell Res., 23, 2013
4GUU
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH TRANYLCYPROMINE
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(3R,3aS,7aR)-10,11-dimethyl-1,4,6-trioxo-3-phenyl-2,3,5,6,7,7a-hexahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4HSU
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3(1-26)IN SPACE GROUP P21
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3, ...
Authors:Chen, F., Dong, Z., Fang, J., Xu, Y.
Deposit date:2012-10-30
Release date:2013-02-13
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.988 Å)
Cite:Structural insight into substrate recognition by histone demethylase LSD2/KDM1b.
Cell Res., 23, 2013
4GY5
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CRYSTAL STRUCTURE OF THE TANDEM TUDOR DOMAIN AND PLANT HOMEODOMAIN OF UHRF1 WITH HISTONE H3K9ME3
Descriptor:E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION
Authors:Cheng, J., Yang, Y., Fang, J., Xiao, J., Zhu, T., Chen, F., Wang, P., Xu, Y.
Deposit date:2012-09-05
Release date:2012-11-14
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.956 Å)
Cite:Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
6MZC
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HUMAN TFIID BC CORE
Descriptor:Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 4, Transcription initiation factor TFIID subunit 5, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZD
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HUMAN TFIID LOBE A CANONICAL
Descriptor:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 3, Transcription initiation factor TFIID subunit 4, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZL
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HUMAN TFIID CANONICAL STATE
Descriptor:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 3, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZM
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HUMAN TFIID BOUND TO PROMOTER DNA AND TFIIA
Descriptor:Transcription initiation factor TFIID subunit 1, TAF1, Transcription initiation factor TFIID subunit 2, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
1HWY
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BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE
Descriptor:GLUTAMATE DEHYDROGENASE, PHOSPHATE ION, 2-OXOGLUTARIC ACID, ...
Authors:Smith, T.J., Peterson, P.E., Schmidt, T., Fang, J., Stanley, C.A.
Deposit date:2001-01-10
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
J.Mol.Biol., 307, 2001
1L1F
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STRUCTURE OF HUMAN GLUTAMATE DEHYDROGENASE-APO FORM
Descriptor:Glutamate Dehydrogenase 1
Authors:Smith, T.J., Schmidt, T., Fang, J., Wu, J., Siuzdak, G., Stanley, C.A.
Deposit date:2002-02-15
Release date:2002-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of apo human glutamate dehydrogenase details subunit communication and allostery.
J.Mol.Biol., 318, 2002
3J1Z
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INWARD-FACING CONFORMATION OF THE ZINC TRANSPORTER YIIP REVEALED BY CRYO-ELECTRON MICROSCOPY
Descriptor:Cation efflux family protein
Authors:Coudray, N., Valvo, S., Hu, M., Lasala, R., Kim, C., Vink, M., Zhou, M., Provasi, D., Filizola, M., Tao, J., Fang, J., Penczek, P.A., Ubarretxena-Belandia, I., Stokes, D.L., Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS)
Deposit date:2012-07-24
Release date:2012-10-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 110, 2013
3R45
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STRUCTURE OF A CENP-A-HISTONE H4 HETERODIMER IN COMPLEX WITH CHAPERONE HJURP
Descriptor:Histone H3-like centromeric protein A, Histone H4, Holliday junction recognition protein, ...
Authors:Hu, H., Liu, Y., Wang, M., Fang, J., Huang, H., Yang, N., Li, Y., Wang, J., Yao, X., Shi, Y., Li, G., Xu, R.M.
Deposit date:2011-03-17
Release date:2011-04-06
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP
Genes Dev., 25, 2011
4YOC
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CRYSTAL STRUCTURE OF HUMAN DNMT1 AND USP7/HAUSP COMPLEX
Descriptor:DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION
Authors:Cheng, J., Yang, H., Fang, J., Gong, R., Wang, P., Li, Z., Xu, Y.
Deposit date:2015-03-11
Release date:2015-05-27
Method:X-RAY DIFFRACTION (2.916 Å)
Cite:Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.
Nat Commun, 6, 2015
5C56
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CRYSTAL STRUCTURE OF USP7/HAUSP IN COMPLEX WITH ICP0
Descriptor:Ubiquitin E3 ligase ICP0, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Cheng, J., Li, Z., Gong, R., Fang, J., Yang, Y., Sun, C., Yang, H., Xu, Y.
Deposit date:2015-06-19
Release date:2015-07-08
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2.685 Å)
Cite:Molecular mechanism for the substrate recognition of USP7.
Protein Cell, 6, 2015
1NQT
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CRYSTAL STRUCTURE OF BOVINE GLUTAMATE DEHYDROGENASE-ADP COMPLEX
Descriptor:Glutamate dehydrogenase 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Banerjee, S., Schmidt, T., Fang, J., Stanley, C.A., Smith, T.J.
Deposit date:2003-01-23
Release date:2003-05-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation
Biochemistry, 42, 2003
1NR1
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CRYSTAL STRUCTURE OF THE R463A MUTANT OF HUMAN GLUTAMATE DEHYDROGENASE
Descriptor:Glutamate dehydrogenase 1
Authors:Banerjee, S., Schmidt, T., Fang, J., Stanley, C.A., Smith, T.J.
Deposit date:2003-01-23
Release date:2003-05-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation
Biochemistry, 42, 2003