Author results

2L97
  • Download 2l97
  • View 2l97
Molmil generated image of 2l97
SOLUTION STRUCTURE OF HTRA PDZ DOMAIN FROM STREPTOCOCCUS PNEUMONIAE
分子名称:Putative serine protease
著者Fan, K., Zhang, J., Zhang, X., Tu, X.
登録日2011-02-02
公開日2012-01-18
実験手法SOLUTION NMR
主引用文献Solution structure of HtrA PDZ domain from Streptococcus pneumoniae and its interaction with YYF-COOH containing peptides.
J.Struct.Biol., 176, 2011
5F9P
  • Download 5f9p
  • View 5f9p
Molmil generated image of 5f9p
CRYSTAL STRUCTURE STUDY OF ANTHRONE OXIDASE-LIKE PROTEIN
分子名称:Anthrone oxidase-like protein, GLYCEROL
著者Gao, X., Wu, D., Fan, K., Liu, Z.-J.
登録日2015-12-10
公開日2016-12-14
最終更新日2018-07-18
実験手法X-RAY DIFFRACTION (2.078 Å)
主引用文献Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis
ACS Chem. Biol., 12, 2017
2KI0
  • Download 2ki0
  • View 2ki0
Molmil generated image of 2ki0
NMR STRUCTURE OF A DE NOVO DESIGNED BETA ALPHA BETA
分子名称:DS119
著者Liang, H., Chen, H., Fan, K., Wei, P., Guo, X., Jin, C., Zeng, C., Tang, C., Lai, L.
登録日2009-04-18
公開日2009-10-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献De novo design of a beta alpha beta motif.
Angew.Chem.Int.Ed.Engl., 48, 2009
2L83
  • Download 2l83
  • View 2l83
Molmil generated image of 2l83
A PROTEIN FROM HALOFERAX VOLCANII
分子名称:Small archaeal modifier protein 1
著者Zhang, W., Liao, S., Fan, K., Tu, X.
登録日2011-01-03
公開日2012-01-11
実験手法SOLUTION NMR
主引用文献A protein from Haloferax volcanii
To be Published
2LJI
  • Download 2lji
  • View 2lji
Molmil generated image of 2lji
STRUCTURE OF A PROTEIN FROM HALOFERAX VOLCANII
分子名称:Small archaeal modifier protein 2
著者Zhang, W., Liao, S., Fan, K.
登録日2011-09-14
公開日2012-10-10
実験手法SOLUTION NMR
主引用文献Structure of a protein from Haloferax volcanii
To be Published
2L32
  • Download 2l32
  • View 2l32
Molmil generated image of 2l32
SOLUTION STRUCTURE OF UBIQUITIN-LIKE SMALL ARCHAEAL MODIFIER PROTEIN IN HALOFERAX VOLCANII
分子名称:Small archaeal modifier protein 2
著者Zhang, W., Fan, K., Liao, S., Tu, X.
登録日2010-09-01
公開日2011-10-05
実験手法SOLUTION NMR
主引用文献solution structure of ubiquitin-like small archaeal modifier protein in Haloferax volcanii
To be Published
3IGB
  • Download 3igb
  • View 3igb
Molmil generated image of 3igb
BACE-1 WITH COMPOUND 3
分子名称:Beta-secretase 1, 8,8-diphenyl-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine
著者Olland, A.M.
登録日2009-07-27
公開日2009-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.238 Å)
主引用文献Aminoimidazoles as potent and selective human beta-secretase (BACE1) inhibitors
J.Med.Chem., 52, 2009
3IN3
  • Download 3in3
  • View 3in3
Molmil generated image of 3in3
BACE1 WITH COMPOUND 30
分子名称:Beta-secretase 1, (5S)-2-amino-3-methyl-5-pyridin-4-yl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one
著者Olland, A.M.
登録日2009-08-11
公開日2010-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem., 18, 2010
3IN4
  • Download 3in4
  • View 3in4
Molmil generated image of 3in4
BACE1 WITH COMPOUND 38
分子名称:Beta-secretase 1, (5S)-2-amino-5-(2,6-diethylpyridin-4-yl)-3-methyl-5-(3-pyrimidin-5-ylphenyl)-3,5-dihydro-4H-imidazol-4-one
著者Olland, A.M.
登録日2009-08-11
公開日2010-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem., 18, 2010
3L38
  • Download 3l38
  • View 3l38
Molmil generated image of 3l38
BACE1 IN COMPLEX WITH THE AMINOPYRIDINE COMPOUND 44
分子名称:Beta-secretase 1, 6-({2-(2-chlorophenyl)-5-[4-(pyrimidin-5-yloxy)phenyl]-1H-pyrrol-1-yl}methyl)pyridin-2-amine
著者Olland, A.M., Chopra, R.
登録日2009-12-16
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3L3A
  • Download 3l3a
  • View 3l3a
Molmil generated image of 3l3a
BACE-1 WITH THE AMINOPYRIDINE COMPOUND 32
分子名称:Beta-secretase 1, 4-(4-{1-[(6-aminopyridin-2-yl)methyl]-5-(2-chlorophenyl)-1H-pyrrol-2-yl}phenoxy)butanenitrile
著者Olland, A.M., Chopra, R.
登録日2009-12-16
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.362 Å)
主引用文献Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3OOZ
  • Download 3ooz
  • View 3ooz
Molmil generated image of 3ooz
BACE1 IN COMPLEX WITH THE AMINOHYDANTOIN COMPOUND 102
分子名称:Beta-secretase 1, (5R)-2-amino-5-[4-(difluoromethoxy)phenyl]-5-[4-fluoro-3-(5-fluoropent-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one
著者Olland, A.M.
登録日2010-08-31
公開日2011-08-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design and Synthesis of Aminohydantoins as Potent and Selective Human beta-Secretase (BACE1) Inhibitors with Enhanced Brain Permeability
Bioorg.Med.Chem.Lett., 20, 2010
2M1H
  • Download 2m1h
  • View 2m1h
Molmil generated image of 2m1h
SOLUTION STRUCTURE OF A PWWP DOMAIN FROM TRYPANOSOMA BRUCEI
分子名称:Transcription elongation factor S-II
著者Wang, R., Fan, K., Liao, S., Zhang, J., Tu, X.
登録日2012-11-28
公開日2013-12-04
最終更新日2016-06-22
実験手法SOLUTION NMR
主引用文献Solution structure of TbTFIIS2-1 PWWP domain from Trypanosoma brucei.
Proteins, 84, 2016
3IND
  • Download 3ind
  • View 3ind
Molmil generated image of 3ind
BACE1 WITH THE AMINOHYDANTOIN COMPOUND 29
分子名称:Beta-secretase 1, (5S)-2-amino-3-methyl-5-phenyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]-3,5-dihydro-4H-imidazol-4-one
著者Olland, A.M., Chopra, R.
登録日2009-08-12
公開日2010-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.246 Å)
主引用文献Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
J.Med.Chem., 53, 2010
3INE
  • Download 3ine
  • View 3ine
Molmil generated image of 3ine
BACE1 WITH THE AMINOHYDANTOIN COMPOUND S-34
分子名称:Beta-secretase 1, (5S)-2-amino-5-(4-methoxy-3-methylphenyl)-3-methyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]-3,5-dihydro-4H-imidazol-4-one
著者Olland, A.M., Chopra, R.
登録日2009-08-12
公開日2010-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
J.Med.Chem., 53, 2010
3INF
  • Download 3inf
  • View 3inf
Molmil generated image of 3inf
BACE1 WITH THE AMINOHYDANTOIN COMPOUND 37
分子名称:Beta-secretase 1, (5S)-2-amino-5-(4-methoxy-3-methylphenyl)-3-methyl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one
著者Olland, A.M., Chopra, R.
登録日2009-08-12
公開日2010-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
J.Med.Chem., 53, 2010
3INH
  • Download 3inh
  • View 3inh
Molmil generated image of 3inh
BACE1 WITH THE AMINOHYDANTOIN COMPOUND R-58
分子名称:Beta-secretase 1, (5R)-2-amino-5-(4-fluoro-3-pyrimidin-5-ylphenyl)-3-methyl-5-[4-(trifluoromethoxy)phenyl]-3,5-dihydro-4H-imidazol-4-one
著者Olland, A.M., Chopra, R.
登録日2009-08-12
公開日2010-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
J.Med.Chem., 53, 2010
3MTS
  • Download 3mts
  • View 3mts
Molmil generated image of 3mts
CHROMO DOMAIN OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1
分子名称:Histone-lysine N-methyltransferase SUV39H1
著者Lam, R., Li, Z., Wang, J., Crombet, L., Walker, J.R., Ouyang, H., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-30
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3.
Plos One, 7, 2012
6J0Z
  • Download 6j0z
  • View 6j0z
Molmil generated image of 6j0z
CRYSTAL STRUCTURE OF ALPK
分子名称:Putative angucycline-like polyketide oxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Wang, W., Liu, Y., Liang, H.
登録日2018-12-27
公開日2019-03-06
実験手法X-RAY DIFFRACTION (2.889 Å)
主引用文献Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin
Biochem. Biophys. Res. Commun., 510, 2019