Author results

2L97
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SOLUTION STRUCTURE OF HTRA PDZ DOMAIN FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Putative serine protease
Authors:Fan, K., Zhang, J., Zhang, X., Tu, X.
Deposit date:2011-02-02
Release date:2012-01-18
Method:SOLUTION NMR
Cite:Solution structure of HtrA PDZ domain from Streptococcus pneumoniae and its interaction with YYF-COOH containing peptides.
J.Struct.Biol., 176, 2011
5F9P
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CRYSTAL STRUCTURE STUDY OF ANTHRONE OXIDASE-LIKE PROTEIN
Descriptor:Anthrone oxidase-like protein, GLYCEROL
Authors:Gao, X., Wu, D., Fan, K., Liu, Z.-J.
Deposit date:2015-12-10
Release date:2016-12-14
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.078 Å)
Cite:Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis
ACS Chem. Biol., 12, 2017
2KI0
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NMR STRUCTURE OF A DE NOVO DESIGNED BETA ALPHA BETA
Descriptor:DS119
Authors:Liang, H., Chen, H., Fan, K., Wei, P., Guo, X., Jin, C., Zeng, C., Tang, C., Lai, L.
Deposit date:2009-04-18
Release date:2009-10-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:De novo design of a beta alpha beta motif.
Angew.Chem.Int.Ed.Engl., 48, 2009
2L83
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A PROTEIN FROM HALOFERAX VOLCANII
Descriptor:Small archaeal modifier protein 1
Authors:Zhang, W., Liao, S., Fan, K., Tu, X.
Deposit date:2011-01-03
Release date:2012-01-11
Method:SOLUTION NMR
Cite:A protein from Haloferax volcanii
To be Published
2LJI
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STRUCTURE OF A PROTEIN FROM HALOFERAX VOLCANII
Descriptor:Small archaeal modifier protein 2
Authors:Zhang, W., Liao, S., Fan, K.
Deposit date:2011-09-14
Release date:2012-10-10
Method:SOLUTION NMR
Cite:Structure of a protein from Haloferax volcanii
To be Published
2L32
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SOLUTION STRUCTURE OF UBIQUITIN-LIKE SMALL ARCHAEAL MODIFIER PROTEIN IN HALOFERAX VOLCANII
Descriptor:Small archaeal modifier protein 2
Authors:Zhang, W., Fan, K., Liao, S., Tu, X.
Deposit date:2010-09-01
Release date:2011-10-05
Method:SOLUTION NMR
Cite:solution structure of ubiquitin-like small archaeal modifier protein in Haloferax volcanii
To be Published
3IGB
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BACE-1 WITH COMPOUND 3
Descriptor:Beta-secretase 1, 8,8-diphenyl-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine
Authors:Olland, A.M.
Deposit date:2009-07-27
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.238 Å)
Cite:Aminoimidazoles as potent and selective human beta-secretase (BACE1) inhibitors
J.Med.Chem., 52, 2009
3IN3
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BACE1 WITH COMPOUND 30
Descriptor:Beta-secretase 1, (5S)-2-amino-3-methyl-5-pyridin-4-yl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one
Authors:Olland, A.M.
Deposit date:2009-08-11
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem., 18, 2010
3IN4
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BACE1 WITH COMPOUND 38
Descriptor:Beta-secretase 1, (5S)-2-amino-5-(2,6-diethylpyridin-4-yl)-3-methyl-5-(3-pyrimidin-5-ylphenyl)-3,5-dihydro-4H-imidazol-4-one
Authors:Olland, A.M.
Deposit date:2009-08-11
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem., 18, 2010
3L38
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BACE1 IN COMPLEX WITH THE AMINOPYRIDINE COMPOUND 44
Descriptor:Beta-secretase 1, 6-({2-(2-chlorophenyl)-5-[4-(pyrimidin-5-yloxy)phenyl]-1H-pyrrol-1-yl}methyl)pyridin-2-amine
Authors:Olland, A.M., Chopra, R.
Deposit date:2009-12-16
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3L3A
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BACE-1 WITH THE AMINOPYRIDINE COMPOUND 32
Descriptor:Beta-secretase 1, 4-(4-{1-[(6-aminopyridin-2-yl)methyl]-5-(2-chlorophenyl)-1H-pyrrol-2-yl}phenoxy)butanenitrile
Authors:Olland, A.M., Chopra, R.
Deposit date:2009-12-16
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.362 Å)
Cite:Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3OOZ
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BACE1 IN COMPLEX WITH THE AMINOHYDANTOIN COMPOUND 102
Descriptor:Beta-secretase 1, (5R)-2-amino-5-[4-(difluoromethoxy)phenyl]-5-[4-fluoro-3-(5-fluoropent-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one
Authors:Olland, A.M.
Deposit date:2010-08-31
Release date:2011-08-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and Synthesis of Aminohydantoins as Potent and Selective Human beta-Secretase (BACE1) Inhibitors with Enhanced Brain Permeability
Bioorg.Med.Chem.Lett., 20, 2010
2M1H
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SOLUTION STRUCTURE OF A PWWP DOMAIN FROM TRYPANOSOMA BRUCEI
Descriptor:Transcription elongation factor S-II
Authors:Wang, R., Fan, K., Liao, S., Zhang, J., Tu, X.
Deposit date:2012-11-28
Release date:2013-12-04
Last modified:2016-06-22
Method:SOLUTION NMR
Cite:Solution structure of TbTFIIS2-1 PWWP domain from Trypanosoma brucei.
Proteins, 84, 2016
3IND
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BACE1 WITH THE AMINOHYDANTOIN COMPOUND 29
Descriptor:Beta-secretase 1, (5S)-2-amino-3-methyl-5-phenyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]-3,5-dihydro-4H-imidazol-4-one
Authors:Olland, A.M., Chopra, R.
Deposit date:2009-08-12
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.246 Å)
Cite:Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
J.Med.Chem., 53, 2010
3INE
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BACE1 WITH THE AMINOHYDANTOIN COMPOUND S-34
Descriptor:Beta-secretase 1, (5S)-2-amino-5-(4-methoxy-3-methylphenyl)-3-methyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]-3,5-dihydro-4H-imidazol-4-one
Authors:Olland, A.M., Chopra, R.
Deposit date:2009-08-12
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
J.Med.Chem., 53, 2010
3INF
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BACE1 WITH THE AMINOHYDANTOIN COMPOUND 37
Descriptor:Beta-secretase 1, (5S)-2-amino-5-(4-methoxy-3-methylphenyl)-3-methyl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one
Authors:Olland, A.M., Chopra, R.
Deposit date:2009-08-12
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.852 Å)
Cite:Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
J.Med.Chem., 53, 2010
3INH
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BACE1 WITH THE AMINOHYDANTOIN COMPOUND R-58
Descriptor:Beta-secretase 1, (5R)-2-amino-5-(4-fluoro-3-pyrimidin-5-ylphenyl)-3-methyl-5-[4-(trifluoromethoxy)phenyl]-3,5-dihydro-4H-imidazol-4-one
Authors:Olland, A.M., Chopra, R.
Deposit date:2009-08-12
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
J.Med.Chem., 53, 2010
3MTS
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CHROMO DOMAIN OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1
Descriptor:Histone-lysine N-methyltransferase SUV39H1
Authors:Lam, R., Li, Z., Wang, J., Crombet, L., Walker, J.R., Ouyang, H., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-04-30
Release date:2010-06-30
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3.
Plos One, 7, 2012
6J0Z
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CRYSTAL STRUCTURE OF ALPK
Descriptor:Putative angucycline-like polyketide oxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Wang, W., Liu, Y., Liang, H.
Deposit date:2018-12-27
Release date:2019-03-06
Method:X-RAY DIFFRACTION (2.889 Å)
Cite:Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin
Biochem. Biophys. Res. Commun., 510, 2019