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6SPF
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PSEUDOMONAS AERUGINOSA 70S RIBOSOME FROM AN AMINOGLYCOSIDE RESISTANT CLINICAL ISOLATE
Descriptor:Pseudomonas aeruginosa strain PAO1 23S ribosomal RNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Halfon, Y., Jimenez-Fernande, A., La Ros, R., Espinos, R., Krogh Johansen, H., Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S., Yonath, A.
Deposit date:2019-09-01
Release date:2019-10-23
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
6SPB
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PSEUDOMONAS AERUGINOSA 50S RIBOSOME FROM A CLINICAL ISOLATE WITH A MUTATION IN UL6
Descriptor:23S ribosomal RNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Halfon, Y., Jimenez-Fernande, A., La Ros, R., Espinos, R., Krogh Johansen, H., Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S., Yonath, A.
Deposit date:2019-09-01
Release date:2019-10-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
6SPC
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PSEUDOMONAS AERUGINOSA 30S RIBOSOME FROM AN AMINOGLYCOSIDE RESISTANT CLINICAL ISOLATE
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Halfon, Y., Jimenez-Fernande, A., La Ros, R., Espinos, R., Krogh Johansen, H., Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S., Yonath, A.
Deposit date:2019-09-01
Release date:2019-10-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
6SPD
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PSEUDOMONAS AERUGINOSA 50S RIBOSOME FROM A CLINICAL ISOLATE
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Halfon, Y., Jimenez-Fernande, A., La Ros, R., Espinos, R., Krogh Johansen, H., Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S., Yonath, A.
Deposit date:2019-09-01
Release date:2019-10-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
6SPE
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PSEUDOMONAS AERUGINOSA 30S RIBOSOME FROM A CLINICAL ISOLATE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Halfon, Y., Jimenez-Fernande, A., La Ros, R., Espinos, R., Krogh Johansen, H., Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S., Yonath, A.
Deposit date:2019-09-01
Release date:2019-10-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
6SPG
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PSEUDOMONAS AERUGINOSA 70S RIBOSOME FROM A CLINICAL ISOLATE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Halfon, Y., Jimenez-Fernande, A., La Ros, R., Espinos, R., Krogh Johansen, H., Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S., Yonath, A.
Deposit date:2019-09-01
Release date:2019-10-16
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
6S0X
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ERYTHROMYCIN RESISTANT STAPHYLOCOCCUS AUREUS 70S RIBOSOME (DELTA R88 A89 UL22) IN COMPLEX WITH ERYTHROMYCIN.
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Halfon, Y., Matozv, D., Eyal, Z., Bashan, A., Zimmerman, E., Kjeldgaard, J., Ingmer, H., Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (2.425 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
6S0Z
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ERYTHROMYCIN RESISTANT STAPHYLOCOCCUS AUREUS 50S RIBOSOME (DELTA R88 A89 UL22) IN COMPLEX WITH ERYTHROMYCIN.
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Halfon, Y., Matozv, D., Eyal, Z., Bashan, A., Zimmerman, E., Kjeldgaard, J., Ingmer, H., Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
6S12
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ERYTHROMYCIN RESISTANT STAPHYLOCOCCUS AUREUS 50S RIBOSOME (DELTA R88 A89 UL22).
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Halfon, Y., Matozv, D., Eyal, Z., Bashan, A., Zimmerman, E., Kjeldgaard, J., Ingmer, H., Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
6S13
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ERYTHROMYCIN RESISTANT STAPHYLOCOCCUS AUREUS 70S RIBOSOME (DELTA R88 A89 UL22).
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Halfon, Y., Matozv, D., Eyal, Z., Bashan, A., Zimmerman, E., Kjeldgaard, J., Ingmer, H., Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
6HMA
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IMPROVED MODEL DERIVED FROM CRYO-EM MAP OF STAPHYLOCOCCUS AUREUS LARGE RIBOSOMAL SUBUNIT
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Cimicata, G., Matzov, D., Fox, T., de Val, N., Zimmerman, E., Bashan, A., Yonath, A.
Deposit date:2018-09-12
Release date:2018-11-14
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit
To Be Published
5NRG
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH RB02
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A., Matzov, D., Eyal, Z., Ben Hamou, R., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M.
Deposit date:2017-04-23
Release date:2017-08-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.442 Å)
Cite:Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
5T7V
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METHICILLIN RESISTANT, LINEZOLID RESISTANT STAPHYLOCOCCUS AUREUS 70S RIBOSOME (DELTA S145 UL3)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Belousoff, M.J., Lithgow, T., Eyal, Z., Yonath, A., Radjainia, M.
Deposit date:2016-09-06
Release date:2017-05-31
Last modified:2018-03-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for Linezolid Binding Site Rearrangement in theStaphylococcus aureusRibosome.
MBio, 8, 2017
5TCU
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METHICILLIN SENSITIVE STAPHYLOCOCCUS AUREUS 70S RIBOSOME
Descriptor:16S RRNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Eyal, Z., Ahmed, T., Belousoff, N., Mishra, S., Matzov, D., Bashan, A., Zimmerman, E., Lithgow, T., Bhushan, S., Yonath, A.
Deposit date:2016-09-15
Release date:2017-05-24
Last modified:2017-09-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
MBio, 8, 2017
5HKV
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LINCOMYCIN
Descriptor:23s ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A., Matzov, D., Eyal, Z., Ben Hamou, R., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M.
Deposit date:2016-01-14
Release date:2017-05-03
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
5HL7
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LEFAMULIN
Descriptor:50S ribosomal protein L2, 23S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Rozenberg, H., Zimmerman, E., Bashan, A., Yonath, A.
Deposit date:2016-01-14
Release date:2016-12-21
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Sci Rep, 6, 2016
5JVG
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THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH AVILAMYCIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Krupkin, M., Wekselman, I., Matzov, D., Eyal, Z., Diskin Posner, Y., Rozenberg, H., Zimmerman, E., Bashan, A., Yonath, A.
Deposit date:2016-05-11
Release date:2016-11-09
Last modified:2019-09-25
Method:X-RAY DIFFRACTION (3.428 Å)
Cite:Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JVH
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THE CRYSTAL STRUCTURE LARGE RIBOSOMAL SUBUNIT (50S) OF DEINOCOCCUS RADIODURANS IN COMPLEX WITH EVERNIMICIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A.
Deposit date:2016-05-11
Release date:2016-11-09
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
4WCE
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.
Deposit date:2014-09-04
Release date:2015-10-21
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (3.526 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WF9
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH TELITHROMYCIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.427 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WFA
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LINEZOLID
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (3.392 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WFB
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH BC-3205
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (3.43 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015