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2YIX
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BU of 2yix by Molmil
Triazolopyridine Inhibitors of p38
Descriptor: 1-ethyl-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea, MITOGEN-ACTIVATED PROTEIN KINASE 14
Authors:Millan, D.S, Anderson, M, Bunnage, M.E, Burrows, J.L, Butcher, K.J, Dodd, P.G, Evans, T.J, Fairman, D.A, Han, s, Hughes, S.J, Irving, S.L, Kilty, I.C, Lemaitre, A, Lewthawaite, R.A, Mahke, A, Marr, E, Mathias, J.P, Philip, J, Phillips, C, Smith, R.T, Stefaniak, M.H, Yeadon, M.
Deposit date:2011-05-17
Release date:2011-11-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.
J.Med.Chem., 54, 2011
2YIS
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BU of 2yis by Molmil
triazolopyridine inhibitors of p38 kinase.
Descriptor: 1-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl]-3-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl]phenyl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, MITOGEN-ACTIVATED PROTEIN KINASE 14
Authors:Millan, D.S, Anderson, M, Bazin, R, Bunnage, M.E, Burrows, J.L, Butcher, K.J, Dodd, P.G, Evans, T.J, Fairman, D.A, Hughes, S.J, Irving, S.L, Kilty, I.C, Lemaitre, A, Lewthwaite, R.A, Mahnke, A, Mathais, J.P, Philip, J, Phillips, C, Smith, R.T, Stefaniack, M.H, Yeadon, M.
Deposit date:2011-05-16
Release date:2011-11-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.
J.Med.Chem., 54, 2011
2YIW
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BU of 2yiw by Molmil
triazolopyridine inhibitors of p38 kinase
Descriptor: 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, MITOGEN-ACTIVATED PROTEIN KINASE 14
Authors:Millan, D.S, Anderson, M, Bunnage, M.E, Burrows, J.L, Butcher, K.J, Dodd, P.G, Evans, T.J, Fairman, D.A, Hughes, S.J, Irving, S.L, Kilty, I.C, Lemaitre, A, Lewthwaite, R.A, Mahnke, A, Mathais, J.P, Philip, J, Phillips, C, Smith, R.T, Stefamiak, M.H, Yeadon, M.
Deposit date:2011-05-17
Release date:2011-11-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.
J.Med.Chem., 54, 2011
2CE1
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BU of 2ce1 by Molmil
Structure of reduced Arabidopsis thaliana cytochrome 6A
Descriptor: CYTOCHROME C6, HEME C
Authors:Marcaida, M.J, Schlarb-Ridley, B.G, Worrall, J.A.R, Wastl, J, Evans, T.J, Bendall, D.S, Luisi, B.F, Howe, C.J.
Deposit date:2006-02-02
Release date:2006-07-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of Cytochrome C(6A), a Novel Dithio-Cytochrome of Arabidopsis Thaliana, and its Reactivity with Plastocyanin: Implications for Function.
J.Mol.Biol., 360, 2006
2CE0
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BU of 2ce0 by Molmil
Structure of oxidized Arabidopsis thaliana cytochrome 6A
Descriptor: CYTOCHROME C6, HEME C
Authors:Marcaida, M.J, Schlarb-Ridley, B.G, Worrall, J.A.R, Wastl, J, Evans, T.J, Bendall, D.S, Luisi, B.F, Howe, C.J.
Deposit date:2006-02-01
Release date:2006-07-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structure of Cytochrome C(6A), a Novel Dithio-Cytochrome of Arabidopsis Thaliana, and its Reactivity with Plastocyanin: Implications for Function.
J.Mol.Biol., 360, 2006
4KV3
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BU of 4kv3 by Molmil
Ubiquitin-like domain of the Mycobacterium tuberculosis type VII secretion system protein EccD1 as maltose-binding protein fusion
Descriptor: Chimera fusion protein of ESX-1 secretion system protein eccD1 and Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Korotkov, K.V, Evans, T.J.
Deposit date:2013-05-22
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
4KV2
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BU of 4kv2 by Molmil
Ubiquitin-like domain of the mycobacterium tuberculosis type VII secretion system protein ECCD1
Descriptor: ESX-1 secretion system protein eccD1
Authors:Korotkov, K.V, Evans, T.J.
Deposit date:2013-05-22
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
4F3V
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BU of 4f3v by Molmil
Crystal structure of N-terminal domain of EccA1 ATPase from ESX-1 secretion system of Mycobacterium tuberculosis
Descriptor: ESX-1 secretion system protein EccA1, SAMARIUM (III) ION, SULFATE ION
Authors:Korotkov, K.V, Evans, T.J.
Deposit date:2012-05-09
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the N-terminal domain of EccA1 ATPase from the ESX-1 secretion system of Mycobacterium tuberculosis.
Proteins, 82, 2014
4FTF
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BU of 4ftf by Molmil
Structure of the Type II secretion system pilotin AspS from Vibrio cholerae
Descriptor: ACETATE ION, Alternate secretin pathway subunit S (VC395_1821, VC1703), ...
Authors:Korotkov, K.V, Evans, T.J.
Deposit date:2012-06-27
Release date:2012-11-28
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspS.
Plos Pathog., 9, 2013
4HVL
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BU of 4hvl by Molmil
Structure of a serine protease MycP1, an essential component of the type VII (ESX-1) secretion system
Descriptor: ACETATE ION, CHLORIDE ION, IMIDAZOLE, ...
Authors:Korotkov, K.V, Evans, T.J.
Deposit date:2012-11-06
Release date:2013-05-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
J.Struct.Biol., 184, 2013
4KK7
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BU of 4kk7 by Molmil
Structure of EccB1 from the type VII (ESX-1) secretion system of Mycobacterium tuberculosis.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ESX-1 secretion system protein eccB1, GLYCEROL, ...
Authors:Korotkov, K.V, Evans, T.J.
Deposit date:2013-05-05
Release date:2013-06-19
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
4KG7
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BU of 4kg7 by Molmil
Structure of MycP3 protease from the type VII (ESX-3) secretion system.
Descriptor: CHLORIDE ION, Peptidase S8 and S53, subtilisin, ...
Authors:Korotkov, K.V, Evans, T.J.
Deposit date:2013-04-28
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
J.Struct.Biol., 184, 2013
5CYU
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BU of 5cyu by Molmil
Structure of the soluble domain of EccB1 from the Mycobacterium smegmatis ESX-1 secretion system.
Descriptor: Conserved membrane protein
Authors:Arbing, M.A, Chan, S, Kahng, S, Kim, J, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-07-30
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
5DLB
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BU of 5dlb by Molmil
Crystal structure of chaperone EspG3 of ESX-3 type VII secretion system from Mycobacterium marinum M
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, PLATINUM (II) ION, ...
Authors:Chan, S, Arbing, M.A, Kim, J, Kahng, S, Sawaya, M.R, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-09-04
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
4XWP
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BU of 4xwp by Molmil
Structure of PE-PPE domains of ESX-1 secreted protein EspB, C2221 in presence of Ca
Descriptor: CALCIUM ION, ESX-1 secretion-associated protein EspB
Authors:Korotkov, K.V.
Deposit date:2015-01-28
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4XY3
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BU of 4xy3 by Molmil
Structure of ESX-1 secreted protein EspB
Descriptor: ESX-1 secretion-associated protein EspB
Authors:Wagner, J.M, Korotkov, K.V.
Deposit date:2015-02-01
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4XXN
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BU of 4xxn by Molmil
Structure of PE-PPE domains of ESX-1 secreted protein EspB, I222
Descriptor: CHLORIDE ION, ESX-1 secretion-associated protein EspB, SODIUM ION
Authors:Korotkov, K.V.
Deposit date:2015-01-30
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4XXX
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BU of 4xxx by Molmil
Structure of PE-PPE domains of ESX-1 secreted protein EspB, C2221
Descriptor: CHLORIDE ION, ESX-1 secretion-associated protein EspB, GLYCEROL
Authors:Piton, J, Pojer, F, Korotkov, K.V.
Deposit date:2015-01-30
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4RCL
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BU of 4rcl by Molmil
Structure of EspG3 chaperone from the type VII (ESX-3) secretion system, space group P43212
Descriptor: ESPG3
Authors:Korotkov, K.V.
Deposit date:2014-09-16
Release date:2015-09-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
5SXL
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BU of 5sxl by Molmil
Structure of EspG3 chaperone from the type VII (ESX-3) secretion system, space group P3221
Descriptor: ESX-3 secretion-associated protein EspG3
Authors:Korotkov, K.V.
Deposit date:2016-08-09
Release date:2016-08-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
5VBA
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BU of 5vba by Molmil
Structure of EspG1 chaperone from the type VII (ESX-1) secretion system determined with the assistance of N-terminal T4 lysozyme fusion
Descriptor: CHLORIDE ION, Lysozyme, ESX-1 secretion-associated protein EspG1 chimera
Authors:Korotkov, K.V.
Deposit date:2017-03-29
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
4L4W
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BU of 4l4w by Molmil
Structure of EspG3 chaperone from the type VII (ESX-3) secretion system
Descriptor: EspG3
Authors:Korotkov, K.V.
Deposit date:2013-06-09
Release date:2014-06-11
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.036 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
4KXR
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BU of 4kxr by Molmil
Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer
Descriptor: EspG5, PE25, PPE41
Authors:Korotkova, N, Creekmore, C.C, Korotkov, K.V.
Deposit date:2013-05-27
Release date:2014-05-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer.
Mol.Microbiol., 94, 2014

217705

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