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4CP3
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THE STRUCTURE OF BCL6 BTB (POZ) DOMAIN IN COMPLEX WITH THE ANSAMYCIN ANTIBIOTIC RIFABUTIN.
Descriptor:B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN
Authors:Evans, S.E., Fairall, L., Goult, B.T., Jamieson, A.G., Ferrigno, P.K., Ford, R., Wagner, S.D., Schwabe, J.W.R.
Deposit date:2014-01-31
Release date:2014-03-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
2K0X
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THE ACTINORHODIN HOLO ACYL CARRIER PROTEIN FROM S. COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, 4'-PHOSPHOPANTETHEINE
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2008-02-15
Release date:2008-09-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein.
Chembiochem, 9, 2008
2K0Y
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THE ACTINORHODIN APO ACYL CARRIER PROTEIN FROM S. COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein
Authors:Crump, M.P., Evans, S.E., Christopher, W.
Deposit date:2008-02-15
Release date:2008-09-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein.
Chembiochem, 9, 2008
2KG6
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SOLUTION STRUCTURE OF THE ACETYL ACTINORHODIN ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, THIOACETIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER
Authors:Crump, M.P., Evans, S.E., Eliza, P., Christopher, W.
Deposit date:2009-03-06
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KG8
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NMR SOLUTION STRUCTURES OF MALONYL ACP FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid
Authors:Crump, M.P., Evans, S.E., Williams, C., Eliza, P.
Deposit date:2009-03-06
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KG9
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NMR SOLUTION STRUCTURES OF BUTYRYL-ACP (A NON-POLAR, NON PATHWAY INTERMEDIATE) FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, THIOBUTYRIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-07
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGA
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NMR SOLUTION STRUCTURES OF HEXANOYL ACP (A NON NATURAL INTERMEDIATE) FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-07
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGC
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NMR SOLUTION STRUCTURES OF OCTANOYL ACP (A NON-NATURAL INTERMEDIATE) FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGD
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NMR SOLUTION STRUCTURES OF 3-OXO-BUTYL-ACP, AN INTERMEDIATE MIMIC FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(3-oxobutyl)sulfanyl]ethyl}-beta-alaninamide
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGE
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NMR SOLUTION STRUCTURES OF 3,5-DIOXOHEXYL ACP (A TRIKETIDE MIMIC) FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, N-{2-[(3,5-dioxohexyl)sulfanyl]ethyl}-N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2PNG
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TYPE I RAT FATTY ACID SYNTHASE ACYL CARRIER PROTEIN (ACP) DOMAIN
Descriptor:Fatty acid synthase (EC 2.3.1.85)
Authors:Ploskon, E.A., Arthur, C.J., Evans, S.E., Williams, C., Crosby, J., Crump, M.P.
Deposit date:2007-04-24
Release date:2007-06-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Mammalian type I Fatty Acid synthase acyl carrier protein domain does not sequester acyl chains.
J.Biol.Chem., 283, 2008
3PHT
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CRYSTAL STRUCTURE OF H74A MUTANT OF HELICOBACTER PYLORI NIKR
Descriptor:Putative nickel-responsive regulator, NICKEL (II) ION
Authors:Pozharski, E., Evans, S., Michel, S.
Deposit date:2010-11-04
Release date:2011-11-23
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect.
Proc.Natl.Acad.Sci.USA, 109, 2012
3QSI
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NICKEL BINDING DOMAIN OF NIKR FROM HELICOBACTER PYLORI DISCLOSING PARTIAL METAL OCCUPANCY
Descriptor:NikR nickel-responsive regulator, NICKEL (II) ION, SULFATE ION
Authors:Gonzalez, J.M., Pozharski, E.
Deposit date:2011-02-21
Release date:2012-04-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect.
Proc.Natl.Acad.Sci.USA, 109, 2012