2VB5
 
 | | Solution structure of W60G mutant of human beta2-microglobulin | | Descriptor: | BETA-2-MICROGLOBULIN | | Authors: | Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V. | | Deposit date: | 2007-09-06 | | Release date: | 2007-09-25 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties.
J.Mol.Biol., 378, 2008
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1FTT
 | | THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN (RATTUS NORVEGICUS) | | Descriptor: | THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN | | Authors: | Fogolari, F, Esposito, G, Damante, G, Formisano, S, Di Lauro, R, Viglino, P. | | Deposit date: | 1995-10-03 | | Release date: | 1996-01-29 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Analysis of the solution structure of the homeodomain of rat thyroid transcription factor 1 by 1H-NMR spectroscopy and restrained molecular mechanics.
Eur.J.Biochem., 241, 1996
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1Y9O
 | | 1H NMR Structure of Acylphosphatase from the hyperthermophile Sulfolobus Solfataricus | | Descriptor: | Acylphosphatase | | Authors: | Corazza, A, Rosano, C, Pagano, K, Alverdi, V, Esposito, G, Capanni, C, Bemporad, F, Plakoutsi, G, Stefani, M, Chiti, F, Zuccotti, S, Bolognesi, M, Viglino, P. | | Deposit date: | 2004-12-16 | | Release date: | 2005-11-29 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus
Proteins, 62, 2006
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2OII
 | | Structure of EMILIN-1 C1q-like domain | | Descriptor: | EMILIN-1 | | Authors: | Verdone, G, Colebrooke, S.A, Corazza, A, Cicero, D.O, Eliseo, T, Viglino, P, Campbell, I.D, Colombatti, A, Esposito, G. | | Deposit date: | 2007-01-11 | | Release date: | 2008-01-22 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the C-terminal domain of EMILIN-1
To be Published
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1JNJ
 | | NMR solution structure of the human beta2-microglobulin | | Descriptor: | beta2-microglobulin | | Authors: | Verdone, G, Corazza, A, Viglino, P, Pettirossi, F, Giorgetti, S, Mangione, P, Andreola, A, Stoppini, M, Bellotti, V, Esposito, G. | | Deposit date: | 2001-07-24 | | Release date: | 2002-02-27 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Protein Sci., 11, 2002
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2KA3
 | | Structure of EMILIN-1 C1Q-like domain | | Descriptor: | EMILIN-1 | | Authors: | Verdone, G, Corazza, A, Colebrooke, S.A, Cicero, D.O, Eliseo, T, Boyd, J, Doliana, R, Fogolari, F, Viglino, P, Colombatti, A, Campbell, I.D, Esposito, G. | | Deposit date: | 2008-10-30 | | Release date: | 2008-11-25 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1
J.Biomol.Nmr, 43, 2009
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2GV1
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7EH3
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1PY4
 | | Beta2 microglobulin mutant H31Y displays hints for amyloid formations | | Descriptor: | Beta-2-microglobulin precursor | | Authors: | Rosano, C, Zuccotti, S, Mangione, P, Giorgetti, S, Bellotti, V, Pettirossi, F, Corazza, A, Viglino, P, Esposito, G, Bolognesi, M. | | Deposit date: | 2003-07-08 | | Release date: | 2004-05-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation
J.Mol.Biol., 335, 2004
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2K27
 | | Solution structure of Human Pax8 Paired Box Domain | | Descriptor: | Paired box protein Pax-8 | | Authors: | Codutti, L, Esposito, G, Corazza, A, Fogolari, F, Tell, G, Vascotto, C, van Ingen, H, Boelens, R, Viglino, P, Quadrifoglio, F. | | Deposit date: | 2008-03-26 | | Release date: | 2008-09-30 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein Family.
J.Biol.Chem., 283, 2008
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2Z9T
 | | Crystal structure of the human beta-2 microglobulin mutant W60G | | Descriptor: | Beta-2-microglobulin | | Authors: | Ricagno, S, Bolognesi, M, Bellotti, V, Corazza, A, Rennella, E, Gural, D, Mimmi, M.C, Betto, E, Pucillo, C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M. | | Deposit date: | 2007-09-26 | | Release date: | 2008-04-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties
J.Mol.Biol., 378, 2008
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3QDA
 | | Crystal structure of W95L beta-2 microglobulin | | Descriptor: | Beta-2-microglobulin, TRIETHYLENE GLYCOL | | Authors: | Ricagno, S, Bellotti, V, Bolognesi, M. | | Deposit date: | 2011-01-18 | | Release date: | 2011-06-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | The two tryptophans of beta2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure.
BMC Evol Biol, 11, 2011
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2BJE
 | | Acylphosphatase from Sulfolobus solfataricus. Monclinic P21 space group | | Descriptor: | ACYLPHOSPHATASE, CHLORIDE ION, SULFATE ION | | Authors: | Rosano, C, Zuccotti, S. | | Deposit date: | 2005-02-02 | | Release date: | 2005-11-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
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2BJD
 | | Sulfolobus Solfataricus Acylphosphatase. Triclinic space group | | Descriptor: | ACYLPHOSPHATASE, CADMIUM ION, CHLORIDE ION, ... | | Authors: | Rosano, C, Zuccotti, S, Bolognesi, M. | | Deposit date: | 2005-02-02 | | Release date: | 2005-11-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
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3MKP
 | | Crystal structure of 1K1 mutant of Hepatocyte Growth Factor/Scatter Factor fragment NK1 in complex with heparin | | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Gherardi, E, Chirgadze, D.Y, Blundell, T.L. | | Deposit date: | 2010-04-15 | | Release date: | 2010-08-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Engineering a fragment of Hepatocyte Growth Factor/Scatter Factor for tissue and organ regeneration
To be Published
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4L3C
 | | Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant | | Descriptor: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | | Authors: | Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S. | | Deposit date: | 2013-06-05 | | Release date: | 2013-12-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
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4L29
 | | Structure of wtMHC class I with NY-ESO1 double mutant | | Descriptor: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | | Authors: | Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S. | | Deposit date: | 2013-06-04 | | Release date: | 2013-12-25 | | Last modified: | 2014-02-26 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
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4M3K
 | | Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis | | Descriptor: | Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S | | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | | Deposit date: | 2013-08-06 | | Release date: | 2014-08-06 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
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4M3J
 | | Structure of a single-domain camelid antibody fragment cAb-H7S specific of the BlaP beta-lactamase from Bacillus licheniformis | | Descriptor: | Camelid heavy-chain antibody variable fragment cAb-H7S, SULFATE ION | | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | | Deposit date: | 2013-08-06 | | Release date: | 2014-08-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
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4N1H
 | | Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis | | Descriptor: | Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N | | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | | Deposit date: | 2013-10-04 | | Release date: | 2014-10-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
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5CKA
 | | Human beta-2 microglobulin double mutant W60G-N83V | | Descriptor: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | | Deposit date: | 2015-07-15 | | Release date: | 2016-05-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
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5CKG
 | | Human beta-2 microglobulin mutant V85E | | Descriptor: | ACETATE ION, Beta-2-microglobulin, GLYCEROL | | Authors: | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | | Deposit date: | 2015-07-15 | | Release date: | 2016-05-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
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5CFH
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7RKT
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7RKW
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