Author results

1EJC
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CRYSTAL STRUCTURE OF UNLIGANDED MURA (TYPE2)
Descriptor:UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE, PHOSPHATE ION, GLYCEROL
Authors:Eschenburg, S., Schonbrunn, E.
Deposit date:2000-03-02
Release date:2000-10-25
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Proteins, 40, 2000
1EJD
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CRYSTAL STRUCTURE OF UNLIGANDED MURA (TYPE1)
Descriptor:UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE, PHOSPHATE ION, CYCLOHEXYLAMMONIUM ION
Authors:Eschenburg, S., Schonbrunn, E.
Deposit date:2000-03-02
Release date:2000-10-25
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Proteins, 40, 2000
1BH6
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SUBTILISIN DY IN COMPLEX WITH THE SYNTHETIC INHIBITOR N-BENZYLOXYCARBONYL-ALA-PRO-PHE-CHLOROMETHYL KETONE
Descriptor:SUBTILISIN DY, CALCIUM ION, SODIUM ION, ...
Authors:Eschenburg, S., Genov, N., Wilson, K.S., Betzel, C.
Deposit date:1998-06-15
Release date:1998-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of subtilisin DY, a random mutant of subtilisin Carlsberg.
Eur.J.Biochem., 257, 1998
1MI4
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GLYPHOSATE INSENSITIVE G96A MUTANT EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE
Descriptor:5-enolpyruvylshikimate-3-phosphate synthase, SHIKIMATE-3-PHOSPHATE, FORMIC ACID
Authors:Eschenburg, S., Healy, M.L., Priestman, M.A., Lushington, G.H., Schonbrunn, E.
Deposit date:2002-08-21
Release date:2002-12-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl shikimate-3-phosphate synthase from Escherichia coli.
PLANTA, 216, 2002
1Q36
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EPSP SYNTHASE (ASP313ALA) LIGANDED WITH TETRAHEDRAL REACTION INTERMEDIATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, 5-(1-CARBOXY-1-PHOSPHONOOXY-ETHOXYL)-4-HYDROXY-3-PHOSPHONOOXY-CYCLOHEX-1-ENECARBOXYLIC ACID, FORMIC ACID
Authors:Eschenburg, S., Kabsch, W., Healy, M.L., Schonbrunn, E.
Deposit date:2003-07-28
Release date:2003-12-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States.
J.Biol.Chem., 278, 2003
1Q3G
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MURA (ASP305ALA) LIGANDED WITH TETRAHEDRAL REACTION INTERMEDIATE
Descriptor:UDP-N-acetylglucosamine 1-carboxyvinyltransferase, 3'-1-CARBOXY-1-PHOSPHONOOXY-ETHOXY-URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, 1,2-ETHANEDIOL
Authors:Eschenburg, S., Kabsch, W., Healy, M.L., Schonbrunn, E.
Deposit date:2003-07-29
Release date:2003-12-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States.
J.Biol.Chem., 278, 2003
1RYW
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C115S MURA LIGANDED WITH REACTION PRODUCTS
Descriptor:UDP-N-acetylglucosamine 1-carboxyvinyltransferase, PHOSPHATE ION, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID, ...
Authors:Eschenburg, S., Schonbrunn, E.
Deposit date:2003-12-22
Release date:2004-11-09
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evidence That the Fosfomycin Target Cys115 in UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA) Is Essential for Product Release.
J.Biol.Chem., 280, 2005
1YBG
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MURA INHIBITED BY A DERIVATIVE OF 5-SULFONOXY-ANTHRANILIC ACID
Descriptor:UDP-N-acetylglucosamine 1-carboxyvinyltransferase, N-METHYL-N-{2-[(2-NAPHTHYLSULFONYL)AMINO]-5-[(2-NAPHTHYLSULFONYL)OXY]BENZOYL}-L-ASPARTIC ACID
Authors:Eschenburg, S., Priestman, M.A., Abdul-Latif, F.A., Delachaume, C., Fassy, F., Schonbrunn, E.
Deposit date:2004-12-20
Release date:2005-02-15
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA).
J.Biol.Chem., 280, 2005
3SFZ
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CRYSTAL STRUCTURE OF FULL-LENGTH MURINE APAF-1
Descriptor:Apoptotic peptidase activating factor 1, ADENOSINE-5'-DIPHOSPHATE, GAMMA-BUTYROLACTONE
Authors:Eschenburg, S., Reubold, T.F.
Deposit date:2011-06-14
Release date:2011-08-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of full-length Apaf-1: how the death signal is relayed in the mitochondrial pathway of apoptosis.
Structure, 19, 2011
3SHF
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CRYSTAL STRUCTURE OF THE R265S MUTANT OF FULL-LENGTH MURINE APAF-1
Descriptor:Apoptotic peptidase activating factor 1, ADENOSINE-5'-DIPHOSPHATE, GAMMA-BUTYROLACTONE
Authors:Eschenburg, S., Reubold, T.F.
Deposit date:2011-06-16
Release date:2011-08-24
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Crystal structure of full-length Apaf-1: how the death signal is relayed in the mitochondrial pathway of apoptosis.
Structure, 19, 2011
1EYN
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STRUCTURE OF MURA LIGANDED WITH THE EXTRINSIC FLUORESCENCE PROBE ANS
Descriptor:UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE, 8-ANILINO-1-NAPHTHALENE SULFONATE, GLYCEROL
Authors:Schonbrunn, E., Eschenburg, S., Luger, K., Kabsch, W., Amrhein, N.
Deposit date:2000-05-07
Release date:2000-06-09
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA.
Proc.Natl.Acad.Sci.USA, 97, 2000
1DLG
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CRYSTAL STRUCTURE OF THE C115S ENTEROBACTER CLOACAE MURA IN THE UN-LIGANDED STATE
Descriptor:UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE MURA, PHOSPHATE ION, CYCLOHEXYLAMMONIUM ION
Authors:Schonbrunn, E., Eschenburg, S., Krekel, F., Luger, K., Amrhein, N.
Deposit date:1999-12-09
Release date:2000-04-12
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA.
Biochemistry, 39, 2000
2AKA
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STRUCTURE OF THE NUCLEOTIDE-FREE MYOSIN II MOTOR DOMAIN FROM DICTYOSTELIUM DISCOIDEUM FUSED TO THE GTPASE DOMAIN OF DYNAMIN 1 FROM RATTUS NORVEGICUS
Descriptor:myosin II heavy chain, LINKER, Dynamin-1
Authors:Reubold, T.F., Eschenburg, S., Becker, A., Leonard, M., Schmid, S.L., Vallee, R.B., Kull, F.J., Manstein, D.J.
Deposit date:2005-08-03
Release date:2005-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the GTPase domain of rat dynamin 1.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1CE7
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MISTLETOE LECTIN I FROM VISCUM ALBUM
Descriptor:PROTEIN (RIBOSOME-INACTIVATING PROTEIN TYPE II), N-ACETYL-D-GLUCOSAMINE
Authors:Krauspenhaar, R., Eschenburg, S., Perbandt, M., Kornilov, V., Konareva, N., Mikailova, I., Stoeva, S., Wacker, R., Maier, T., Singh, T.P., Mikhailov, A., Voelter, W., Betzel, C.
Deposit date:1999-03-18
Release date:2000-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of mistletoe lectin I from Viscum album.
Biochem.Biophys.Res.Commun., 257, 1999
1IC6
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STRUCTURE OF A SERINE PROTEASE PROTEINASE K FROM TRITIRACHIUM ALBUM LIMBER AT 0.98 A RESOLUTION
Descriptor:PROTEINASE K, CALCIUM ION, NITRATE ION
Authors:Betzel, C., Gourinath, S., Kumar, P., Kaur, P., Perbandt, M., Eschenburg, S., Singh, T.P.
Deposit date:2001-03-30
Release date:2001-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution.
Biochemistry, 40, 2001
1NAW
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ENOLPYRUVYL TRANSFERASE
Descriptor:UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYL-TRANSFERASE, CYCLOHEXYLAMMONIUM ION
Authors:Schoenbrunn, E., Sack, S., Eschenburg, S., Perrakis, A., Krekel, F., Amrhein, N., Mandelkow, E.
Deposit date:1996-07-23
Release date:1997-07-23
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin.
Structure, 4, 1996
2MLL
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MISTLETOE LECTIN I FROM VISCUM ALBUM
Descriptor:PROTEIN (RIBOSOME-INACTIVATING PROTEIN TYPE II), N-ACETYL-D-GLUCOSAMINE
Authors:Krauspenhaar, R., Eschenburg, S., Perbandt, M., Kornilov, V., Konareva, N., Mikailova, I., Stoeva, S., Wacker, R., Maier, T., Singh, T.P., Mikhailov, A., Voelter, W., Betzel, C.
Deposit date:1999-03-16
Release date:2000-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of mistletoe lectin I from Viscum album.
Biochem.Biophys.Res.Commun., 257, 1999
1AOK
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VIPOXIN COMPLEX
Descriptor:VIPOXIN COMPLEX, ACETATE ION
Authors:Perbandt, M., Wilson, J.C., Eschenburg, S., Betzel, C.
Deposit date:1997-07-07
Release date:1998-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of vipoxin at 2.0 A: an example of regulation of a toxic function generated by molecular evolution.
FEBS Lett., 412, 1997
1G6S
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STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE AND GLYPHOSATE
Descriptor:EPSP SYNTHASE, SHIKIMATE-3-PHOSPHATE, GLYPHOSATE, ...
Authors:Schonbrunn, E., Eschenburg, S., Shuttleworth, W., Schloss, J.V., Amrhein, N., Evans, J.N.S., Kabsch, W.
Deposit date:2000-11-07
Release date:2001-02-07
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail.
Proc.Natl.Acad.Sci.USA, 98, 2001
1G6T
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STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE
Descriptor:EPSP SYNTHASE, PHOSPHATE ION, SHIKIMATE-3-PHOSPHATE, ...
Authors:Schonbrunn, E., Eschenburg, S., Shuttleworth, W., Schloss, J.V., Amrhein, N., Evans, J.N.S., Kabsch, W.
Deposit date:2000-11-07
Release date:2001-02-07
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail.
Proc.Natl.Acad.Sci.USA, 98, 2001
1L3P
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CRYSTAL STRUCTURE OF THE FUNCTIONAL DOMAIN OF THE MAJOR GRASS POLLEN ALLERGEN PHL P 5B
Descriptor:POLLEN ALLERGEN Phl p 5b, PHOSPHATE ION, MAGNESIUM ION
Authors:Rajashankar, K.R., Bufe, A., Weber, W., Eschenburg, S., Lindner, B., Betzel, C.
Deposit date:2002-02-28
Release date:2003-02-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the functional domain of the major grass-pollen allergen Phlp 5b.
Acta Crystallogr.,Sect.D, 58, 2002
5A3F
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CRYSTAL STRUCTURE OF THE DYNAMIN TETRAMER
Descriptor:DYNAMIN 3
Authors:Reubold, T.F., Faelber, K., Plattner, N., Posor, Y., Branz, K., Curth, U., Schlegel, J., Anand, R., Manstein, D.J., Noe, F., Haucke, V., Daumke, O., Eschenburg, S.
Deposit date:2015-05-29
Release date:2015-08-26
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal Structure of the Dynamin Tetramer
Nature, 525, 2015
5D3Q
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DYNAMIN 1 GTPASE-BSE FUSION DIMER COMPLEXED WITH GDP
Descriptor:Dynamin-1,Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL
Authors:Anand, R., Eschenburg, S., Reubold, T.F.
Deposit date:2015-08-06
Release date:2015-12-02
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the GTPase domain and the bundle signalling element of dynamin in the GDP state.
Biochem.Biophys.Res.Commun., 469, 2016
1HT3
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MERCURY INDUCED MODIFICATIONS IN THE STEREOCHEMISTRY OF THE ACTIVE SITE THROUGH CYS-73 IN A SERINE PROTEASE: CRYSTAL STRUCTURE OF THE COMPLEX OF A PARTIALLY MODIFIED PROTEINASE K WITH MERCURY AT 1.8 A RESOLUTION
Descriptor:PROTEINASE K, MERCURY (II) ION, CALCIUM ION
Authors:Gourinath, S.
Deposit date:2000-12-27
Release date:2001-06-27
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mercury induced modifications in the stereochemistry of the active site through Cys-73 in a serine protease--crystal structure of the complex of a partially modified proteinase K with mercury at 1.8 A resolution
Indian J.Biochem.Biophys., 38, 2001
3J2T
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AN IMPROVED MODEL OF THE HUMAN APOPTOSOME
Descriptor:Apoptotic protease-activating factor 1, Cytochrome c, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Yuan, S., Topf, M., Akey, C.W.
Deposit date:2012-12-23
Release date:2013-04-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Changes in apaf-1 conformation that drive apoptosome assembly.
Biochemistry, 52, 2013
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