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6PAH
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BU of 6pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR
Descriptor: 3,4-DIHYDROXYPHENYLALANINE, FE (III) ION, PHENYLALANINE 4-MONOOXYGENASE
Authors:Erlandsen, H, Flatmark, T, Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
1DMW
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BU of 1dmw by Molmil
CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN
Descriptor: 7,8-DIHYDROBIOPTERIN, FE (III) ION, PHENYLALANINE HYDROXYLASE
Authors:Erlandsen, H, Stevens, R.C, Flatmark, T.
Deposit date:1999-12-15
Release date:2000-03-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase.
Biochemistry, 39, 2000
5PAH
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BU of 5pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND DOPAMINE INHIBITOR
Descriptor: FE (III) ION, L-DOPAMINE, PHENYLALANINE 4-MONOOXYGENASE
Authors:Erlandsen, H, Flatmark, T, Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
3PAH
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BU of 3pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND ADRENALINE INHIBITOR
Descriptor: 4-[(1S)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, FE (III) ION, PHENYLALANINE HYDROXYLASE
Authors:Erlandsen, H, Flatmark, T, Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
1TG2
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BU of 1tg2 by Molmil
Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound
Descriptor: 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, FE (III) ION, Phenylalanine-4-hydroxylase
Authors:Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C.
Deposit date:2004-05-28
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1TDW
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BU of 1tdw by Molmil
Crystal structure of double truncated human phenylalanine hydroxylase BH4-responsive PKU mutant A313T.
Descriptor: FE (III) ION, Phenylalanine-4-hydroxylase
Authors:Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C.
Deposit date:2004-05-24
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101, 2004
4PAH
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BU of 4pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND NOR-ADRENALINE INHIBITOR
Descriptor: FE (III) ION, L-NOREPINEPHRINE, PHENYLALANINE HYDROXYLASE
Authors:Erlandsen, H, Flatmark, T, Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
1LTU
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BU of 1ltu by Molmil
CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM, APO (NO IRON BOUND) STRUCTURE
Descriptor: PHENYLALANINE-4-HYDROXYLASE
Authors:Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C.
Deposit date:2002-05-20
Release date:2002-07-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTZ
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BU of 1ltz by Molmil
CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE HAS BOUND IRON (III) AND OXIDIZED COFACTOR 7,8-DIHYDROBIOPTERIN
Descriptor: 7,8-DIHYDROBIOPTERIN, CHLORIDE ION, FE (III) ION, ...
Authors:Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C.
Deposit date:2002-05-21
Release date:2002-07-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTV
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BU of 1ltv by Molmil
CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE WITH BOUND OXIDIZED Fe(III)
Descriptor: FE (III) ION, PHENYLALANINE-4-HYDROXYLASE
Authors:Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C.
Deposit date:2002-05-20
Release date:2002-07-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1PAH
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BU of 1pah by Molmil
HUMAN PHENYLALANINE HYDROXYLASE DIMER, RESIDUES 117-424
Descriptor: FE (III) ION, PHENYLALANINE HYDROXYLASE
Authors:Stevens, R.C, Erlandsen, H.
Deposit date:1997-10-25
Release date:1999-01-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria.
Nat.Struct.Biol., 4, 1997
2FRX
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BU of 2frx by Molmil
Crystal structure of YebU, a m5C RNA methyltransferase from E.coli
Descriptor: Hypothetical protein yebU
Authors:Erlandsen, H, Nordlund, P, Hallberg, B.M, Johnson, K.A, Ericsson, U.B.
Deposit date:2006-01-20
Release date:2006-08-29
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain
J.Mol.Biol., 360, 2006
7MYM
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BU of 7mym by Molmil
Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM and NADPH
Descriptor: ARGININE, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Erlandsen, H, Wright, D, Krucinska, J.
Deposit date:2021-05-21
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
Commun Biol, 5, 2022
7MYL
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BU of 7myl by Molmil
Crystal structure of DfrA1 dihydrofolate reductase in complex with TRIMETHOPRIM
Descriptor: Dihydrofolate reductase, TRIMETHOPRIM
Authors:Erlandsen, H, Wright, D.
Deposit date:2021-05-21
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
Commun Biol, 5, 2022
6BFZ
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BU of 6bfz by Molmil
Crystal structure of enolase from E. coli with a mixture of apo form, substrate, and product form
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-PHOSPHOGLYCERIC ACID, Enolase, ...
Authors:Erlandsen, H, Wright, D, Krucinska, J.
Deposit date:2017-10-27
Release date:2018-10-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
Biochemistry, 58, 2019
6BFY
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BU of 6bfy by Molmil
Crystal structure of enolase from Escherichia coli with bound 2-phosphoglycerate substrate
Descriptor: 2-PHOSPHOGLYCERIC ACID, Enolase, GLYCEROL, ...
Authors:Erlandsen, H, Wright, D, Krucinska, J.
Deposit date:2017-10-27
Release date:2018-10-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
Biochemistry, 58, 2019
6D3L
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BU of 6d3l by Molmil
Crystal structure of unphosphorylated human PKR
Descriptor: Interferon-induced, double-stranded RNA-activated protein kinase
Authors:Erlandsen, H, Mayo, C, Robinson, V.L, Cole, J.L.
Deposit date:2018-04-16
Release date:2019-07-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Protein Kinase R Autophosphorylation.
Biochemistry, 58, 2019
6D3Q
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BU of 6d3q by Molmil
Crystal structure of Escherichia coli enolase complexed with a natural inhibitor SF2312.
Descriptor: Enolase, GLYCEROL, MAGNESIUM ION, ...
Authors:Erlandsen, H, Krucinska, J, Hazeen, A, Wright, D.
Deposit date:2018-04-16
Release date:2019-11-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.
Sci Rep, 9, 2019
6D3K
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BU of 6d3k by Molmil
Crystal structure of unphosphorylated human PKR kinase domain in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced, double-stranded RNA-activated protein kinase, ...
Authors:Erlandsen, H, Mayo, C.B, Robinson, V.L, Cole, J.L.
Deposit date:2018-04-16
Release date:2019-07-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis of Protein Kinase R Autophosphorylation.
Biochemistry, 58, 2019
6NPF
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BU of 6npf by Molmil
Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite.
Descriptor: Enolase, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Erlandsen, H, Krucinska, J, Lombardo, M, Wright, D.
Deposit date:2019-01-17
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.
Sci Rep, 9, 2019
7NAE
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BU of 7nae by Molmil
Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM
Descriptor: Dihydrofolate reductase, SULFATE ION, TRIMETHOPRIM
Authors:Estrada, A, Wright, D, Krucinska, J, Erlandsen, H.
Deposit date:2021-06-21
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
Commun Biol, 5, 2022
3FHD
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BU of 3fhd by Molmil
Crystal structure of the Shutoff and Exonuclease Protein from Kaposis Sarcoma Associated Herpesvirus
Descriptor: MAGNESIUM ION, ORF 37, SULFATE ION
Authors:Dahlroth, S.L, Gurmu, D, Schmitzberger, F, Haas, J, Erlandsen, H, Nordlund, P.
Deposit date:2008-12-09
Release date:2009-11-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the shutoff and exonuclease protein from the oncogenic Kaposi's sarcoma-associated herpesvirus
Febs J., 276, 2009
2VEC
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BU of 2vec by Molmil
The crystal structure of the protein YhaK from Escherichia coli
Descriptor: CHLORIDE ION, PIRIN-LIKE PROTEIN YHAK
Authors:Gurmu, D, Lu, J, Johnson, K.A, Nordlund, P, Holmgren, A, Erlandsen, H.
Deposit date:2007-10-18
Release date:2008-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Crystal Structure of the Protein Yhak from Escherichia Coli Reveals a New Subclass of Redox Sensitive Enterobacterial Bicupins.
Proteins, 74, 2008
2PAH
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BU of 2pah by Molmil
TETRAMERIC HUMAN PHENYLALANINE HYDROXYLASE
Descriptor: FE (III) ION, PROTEIN (PHENYLALANINE HYDROXYLASE)
Authors:Stevens, R.C, Fusetti, F, Erlandsen, H.
Deposit date:1998-05-26
Release date:1999-10-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria.
J.Biol.Chem., 273, 1998
3QKW
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BU of 3qkw by Molmil
Structure of Streptococcus parasangunini Gtf3 glycosyltransferase
Descriptor: Nucleotide sugar synthetase-like protein, URIDINE-5'-DIPHOSPHATE
Authors:Zhu, F, Erlandsen, H, Huang, Y, Ding, L, Zhou, M, Liang, X, Ma, J.-B, Wu, H.
Deposit date:2011-02-01
Release date:2011-06-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.287 Å)
Cite:Structural and Functional Analysis of a New Subfamily of Glycosyltransferases Required for Glycosylation of Serine-rich Streptococcal Adhesins.
J.Biol.Chem., 286, 2011

 

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