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6EZ0
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SPECIFIC PHOSPHOROTHIOATE SUBSTITUTION WITHIN DOMAIN 6 OF A GROUP II INTRON RIBOZYME LEADS TO CHANGES IN LOCAL STRUCTURE AND METAL ION BINDING
Descriptor:RNA (27-MER)
Authors:Erat, M.C., Besic, E., Oberhuber, M., Johannsen, S., Sigel, R.K.O.
Deposit date:2017-11-13
Release date:2018-01-03
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Specific phosphorothioate substitution within domain 6 of a group II intron ribozyme leads to changes in local structure and metal ion binding.
J. Biol. Inorg. Chem., 23, 2018
2AHT
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SOLUTION STRUCTURE OF DOMAIN 6 FROM THE AI5(GAMMA)GROUP II INTRON
Descriptor:27-MER
Authors:Erat, M.C., Zerbe, O., Fox, T., Sigel, R.K.O.
Deposit date:2005-07-28
Release date:2006-10-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of domain 6 from a self-splicing group II intron ribozyme: a Mg(2+) binding site is located close to the stacked branch adenosine.
Chembiochem, 8, 2007
3EJH
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CRYSTAL STRUCTURE OF THE FIBRONECTIN 8-9FNI DOMAIN PAIR IN COMPLEX WITH A TYPE-I COLLAGEN PEPTIDE
Descriptor:Fibronectin, Collagen type-I a1 chain, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Erat, M.C., Lowe, E.D., Campbell, I.D., Vakonakis, I.
Deposit date:2008-09-18
Release date:2009-02-03
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and structural analysis of type I collagen sites in complex with fibronectin fragments.
Proc.Natl.Acad.Sci.USA, 106, 2009
3MQL
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CRYSTAL STRUCTURE OF THE FIBRONECTIN 6FNI1-2FNII7FNI FRAGMENT
Descriptor:Fibronectin 1, N-ACETYL-D-GLUCOSAMINE, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Erat, M.C., Campbell, I.D., Vakonakis, I.
Deposit date:2010-04-28
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI
J.Biol.Chem., 285, 2010
4G79
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STRUCTURE A C. ELEGANS SAS-6 VARIANT
Descriptor:Spindle assembly abnormal protein 6, GLYCEROL, TETRAETHYLENE GLYCOL
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-07-20
Release date:2013-06-19
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GEU
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STRUCTURE OF A STABILISED CESAS-6 DIMER
Descriptor:Spindle assembly abnormal protein 6, GLYCEROL, TETRAETHYLENE GLYCOL
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-08-02
Release date:2013-06-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GEX
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STRUCTURE OF A STABILISED CESAS-6 DIMER, SECOND CRYSTAL FORM
Descriptor:Spindle assembly abnormal protein 6, SULFATE ION
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-08-02
Release date:2013-06-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GFA
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N-TERMINAL COILED-COIL DIMER OF C.ELEGANS SAS-6, CRYSTAL FORM A
Descriptor:Spindle assembly abnormal protein 6, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-08-03
Release date:2013-06-19
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GFC
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N-TERMINAL COILED-COIL DIMER OF C.ELEGANS SAS-6, CRYSTAL FORM B
Descriptor:Spindle assembly abnormal protein 6, 1,2-ETHANEDIOL, IMIDAZOLE, ...
Authors:Erat, M.C., Vakonakis, I.
Deposit date:2012-08-03
Release date:2013-06-19
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
2LKL
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STRUCTURE OF THE CORE INTRACELLULAR DOMAIN OF PFEMP1
Descriptor:Erythrocyte membrane protein 1 (PfEMP1)
Authors:Vakonakis, I., Erat, M.C.
Deposit date:2011-10-16
Release date:2012-01-25
Last modified:2012-03-21
Method:SOLUTION NMR
Cite:Structural Analysis of the Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Intracellular Domain Reveals a Conserved Interaction Epitope.
J.Biol.Chem., 287, 2012
3Q0X
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N-TERMINAL COILED-COIL DIMER DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P
Descriptor:Centriole protein
Authors:Kitagawa, D., Vakonakis, I., Olieric, N., Hilbert, M., Keller, D., Olieric, V., Bortfeld, M., Erat, M.C., Flueckiger, I., Goenczy, P., Steinmetz, M.O.
Deposit date:2010-12-16
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
3Q0Y
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P
Descriptor:Centriole protein
Authors:Kitagawa, D., Vakonakis, I., Olieric, N., Hilbert, M., Keller, D., Olieric, V., Bortfeld, M., Erat, M.C., Flueckiger, I., Goenczy, P., Steinmetz, M.O.
Deposit date:2010-12-16
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
4LZF
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A NOVEL DOMAIN IN THE MICROCEPHALY PROTEIN CPAP SUGGESTS A ROLE IN CENTRIOLE ARCHITECTURE
Descriptor:Centrosomal P4.1-associated protein, SCL-interrupting locus protein homolog, TRIETHYLENE GLYCOL, ...
Authors:Hatzopoulos, G.N., Erat, M.C., Cutts, E., Rogala, K., Slatter, L., Stansfeld, P.J., Vakonakis, I.
Deposit date:2013-07-31
Release date:2013-09-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.
Structure, 21, 2013
3GXE
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COMPLEX OF A LOW AFFINITY COLLAGEN SITE WITH THE FIBRONECTIN 8-9FNI DOMAIN PAIR
Descriptor:Fibronectin, Collagen alpha-1(I) chain, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Sladek, B., Campbell, I.D., Vakonakis, I.
Deposit date:2009-04-02
Release date:2010-04-07
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode
J.Biol.Chem., 288, 2013
3PYI
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STRUCTURE OF THE N-TERMINAL DOMAIN OF C. ELEGANS SAS-6
Descriptor:Spindle assembly abnormal protein 6, TETRAETHYLENE GLYCOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Vakonakis, I., Steinmetz, M.O.
Deposit date:2010-12-13
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
4JLE
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STRUCTURE OF THE P. FALCIPARUM PFI1780W PHIST DOMAIN
Descriptor:PHIST, CHLORIDE ION, ACETATE ION
Authors:Slater, L., Vakonakis, I.
Deposit date:2013-03-12
Release date:2014-04-16
Last modified:2015-03-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A Plasmodium falciparum PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface.
Faseb J., 28, 2014
4LD1
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STRUCTURAL ANALYSIS OF THE MICROCEPHALY PROTEIN CPAP G-BOX DOMAIN SUGGESTS A ROLE IN CENTRIOLE ELONGATION.
Descriptor:Uncharacterized protein, NITRATE ION, TRIETHYLENE GLYCOL, ...
Authors:Hatzopoulos, G.N., Vakonakis, I.
Deposit date:2013-06-24
Release date:2013-09-04
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.
Structure, 21, 2013
4LD3
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STRUCTURAL ANALYSIS OF THE MICROCEPHALY PROTEIN CPAP G-BOX DOMAIN SUGGESTS A ROLE IN CENTRIOLE ELONGATION.
Descriptor:Uncharacterized protein, SCL-interrupting locus protein homolog, ISOPROPYL ALCOHOL, ...
Authors:Hatzopoulos, G.N., Vakonakis, I.
Deposit date:2013-06-24
Release date:2013-09-04
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.
Structure, 21, 2013
4TPZ
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P F145W (NN2)
Descriptor:Centriole protein
Authors:Hilbert, M., Kraatz, S.H.W.
Deposit date:2014-06-10
Release date:2015-06-24
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016
4TO7
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P Q93E F145W K146R (NN24)
Descriptor:Centriole protein
Authors:Hilbert, M., Kraatz, S.H.W.
Deposit date:2014-06-05
Release date:2015-06-17
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (1.252 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016
4TQ7
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P Q93E (NN10)
Descriptor:Centriole protein
Authors:Hilbert, M., Kraatz, S.H.W.
Deposit date:2014-06-10
Release date:2015-06-24
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2.643 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016
4TTW
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P K105C F145C (NN18)
Descriptor:Centriole protein
Authors:Hilbert, M., Kraatz, S.H.W.
Deposit date:2014-06-23
Release date:2015-07-01
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016
4TTX
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P VARIANT G94C K146C (NN19)
Descriptor:Centriole protein
Authors:Hilbert, M., Kraatz, S.H.W.
Deposit date:2014-06-23
Release date:2015-07-01
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016
4TTZ
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P VARIANT G94E F145W Q147K (NN26)
Descriptor:Centriole protein
Authors:Hilbert, M., Kraatz, S.H.W.
Deposit date:2014-06-23
Release date:2015-07-01
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016
4U2J
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P VARIANT Q93E F145W (NN27)
Descriptor:Centriole protein
Authors:Hilbert, M., Kraatz, S.H.W.
Deposit date:2014-07-17
Release date:2015-07-29
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016