Author results

5E2C
  • Download 5e2c
  • View 5e2c
Molmil generated image of 5e2c
CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF CYTOPLASMIC PEPTIDASE PEPQ FROM MYCOBACTERIUM TUBERCULOSIS H37RV
分子名称:Xaa-Pro dipeptidase
著者Chang, C., Endres, L., Endres, M., SACCHETTINI, J., JOACHIMIAK, A., Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI)
登録日2015-09-30
公開日2015-10-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of N-terminal domain of cytoplasmic peptidase PepQ from Mycobacterium tuberculosis H37Rv
To Be Published
4NPX
  • Download 4npx
  • View 4npx
Molmil generated image of 4npx
STRUCTURE OF HYPOTHETICAL PROTEIN CJ0539 FROM CAMPYLOBACTER JEJUNI
分子名称:Putative uncharacterized protein
著者Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Adkins, J.N., Endres, M., Nissen, M., Konkel, M., Joachimiak, A., Anderson, W.F., Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
登録日2013-11-22
公開日2014-01-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of hypothetical protein Cj0539 from Campylobacter jejuni
To be Published
5BMO
  • Download 5bmo
  • View 5bmo
Molmil generated image of 5bmo
LNMX PROTEIN, A PUTATIVE GLCNAC-PI DE-N-ACETYLASE FROM STREPTOMYCES ATROOLIVACEUS
分子名称:Putative uncharacterized protein LnmX, POTASSIUM ION, ACETATE ION
著者Osipiuk, J., Hatzos-Skintges, C., Cuff, M., Endres, M., Babnigg, G., Lohman, J., Ma, M., Rudolf, J., Chang, C.-Y., Shen, B., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2015-05-22
公開日2015-06-10
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献LnmX protein, a putative GlcNAc-PI de-N-acetylase from Streptomyces atroolivaceus.
to be published
6QKY
  • Download 6qky
  • View 6qky
Molmil generated image of 6qky
TRYPTOPHAN SYNTHASE SUBUNIT ALPHA FROM STREPTOCOCCUS PNEUMONIAE WITH 3D DOMAIN SWAP IN THE CORE OF TIM BARREL
分子名称:Tryptophan synthase alpha chain, GLYCEROL, ACETIC ACID, ...
著者Michalska, K., Kowiel, M., Bigelow, L., Endres, M., Gilski, M., Jaskolski, M., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-30
公開日2019-03-27
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献3D domain swapping in the TIM barrel of the alpha subunit of Streptococcus pneumoniae tryptophan synthase
To be published
4JWO
  • Download 4jwo
  • View 4jwo
Molmil generated image of 4jwo
THE CRYSTAL STRUCTURE OF A POSSIBLE PHOSPHATE BINDING PROTEIN FROM PLANCTOMYCES LIMNOPHILUS DSM 3776
分子名称:Phosphate binding protein, SULFATE ION, FORMIC ACID, ...
著者Tan, K., Gu, M., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2013-03-27
公開日2013-04-24
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献The crystal structure of a possible phosphate binding protein from Planctomyces limnophilus DSM 3776
To be Published
4OPE
  • Download 4ope
  • View 4ope
Molmil generated image of 4ope
STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMH KS7
分子名称:NRPS/PKS, NITRATE ION
著者Osipiuk, J., Mack, J., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-02-05
公開日2014-02-19
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4OPF
  • Download 4opf
  • View 4opf
Molmil generated image of 4opf
STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMH KS8
分子名称:NRPS/PKS
著者Osipiuk, J., Bigelow, L., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-02-05
公開日2014-02-19
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4OVY
  • Download 4ovy
  • View 4ovy
Molmil generated image of 4ovy
CRYSTAL STRUCTURE OF HALOACID DEHALOGENASE DOMAIN PROTEIN HYDROLASE FROM PLANCTOMYCES LIMNOPHILUS DSM 3776
分子名称:Haloacid dehalogenase domain protein hydrolase, CITRIC ACID, 1,2-ETHANEDIOL, ...
著者Chang, C., Gu, M., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2014-01-24
公開日2014-02-05
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Haloacid dehalogenase domain protein hydrolase from Planctomyces limnophilus DSM 3776
To be published
4QYR
  • Download 4qyr
  • View 4qyr
Molmil generated image of 4qyr
STREPTOMYCES PLATENSIS ISOMIGRASTATIN KETOSYNTHASE DOMAIN MGSE KS3
分子名称:AT-less polyketide synthase, GLYCEROL, ACETIC ACID, ...
著者Kim, Y., Li, H., Endres, M., Babnigg, J., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-07-25
公開日2014-08-20
最終更新日2016-12-07
実験手法X-RAY DIFFRACTION (2.902 Å)
主引用文献Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4TKT
  • Download 4tkt
  • View 4tkt
Molmil generated image of 4tkt
STREPTOMYCES PLATENSIS ISOMIGRASTATIN KETOSYNTHASE DOMAIN MGSF KS6
分子名称:AT-less polyketide synthase, CHLORIDE ION, SULFATE ION, ...
著者Chang, C., Li, H., Endres, M., Bingman, C., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-05-27
公開日2014-06-11
最終更新日2016-11-02
実験手法X-RAY DIFFRACTION (2.4289 Å)
主引用文献Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WKY
  • Download 4wky
  • View 4wky
Molmil generated image of 4wky
STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMN KS2
分子名称:Beta-ketoacyl synthase, SULFATE ION, GLYCEROL, ...
著者Cuff, M.E., Mack, J.C., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-10-03
公開日2014-10-29
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X2R
  • Download 4x2r
  • View 4x2r
Molmil generated image of 4x2r
CRYSTAL STRUCTURE OF PRIA FROM ACTINOMYCES UROGENITALIS
分子名称:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, PHOSPHATE ION, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID
著者MICHALSKA, K., VERDUZCO-CASTRO, E.A., ENDRES, M., BARONA-GOMEZ, F., JOACHIMIAK, A., Midwest Center for Structural Genomics (MCSG)
登録日2014-11-26
公開日2014-12-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Evolution of substrate specificity in a retained enzyme driven by gene loss.
Elife, 6, 2017
4XXT
  • Download 4xxt
  • View 4xxt
Molmil generated image of 4xxt
CRYSTAL STRUCTURE OF FUSED ZN-DEPENDENT AMIDASE/PEPTIDASE/PEPTODOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN FROM CLOSTRIDIUM ACETOBUTYLICUM ATCC 824
分子名称:Fusion of predicted Zn-dependent amidase/peptidase (Cell wall hydrolase/DD-carboxypeptidase family) and uncharacterized domain of ErfK family peptodoglycan-binding domain, 1,2-ETHANEDIOL, ACETATE ION, ...
著者Chang, C., Cuff, M., Joachimiak, G., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2015-01-30
公開日2015-02-18
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal structure of Fused Zn-dependent amidase/peptidase/peptodoglycan-binding domain-containing protein from from Clostridium acetobutylicum ATCC 824
To Be Published
4ZDN
  • Download 4zdn
  • View 4zdn
Molmil generated image of 4zdn
STREPTOMYCES PLATENSIS ISOMIGRASTATIN KETOSYNTHASE DOMAIN MGSF KS4
分子名称:AT-less polyketide synthase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION
著者Chang, C., Li, H., Endres, M., Bingman, C., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2015-04-17
公開日2015-05-13
最終更新日2016-11-02
実験手法X-RAY DIFFRACTION (2.509 Å)
主引用文献Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZTK
  • Download 4ztk
  • View 4ztk
Molmil generated image of 4ztk
TRANSPEPTIDASE DOMAIN OF FTSI4 D,D-TRANSPEPTIDASE FROM LEGIONELLA PNEUMOPHILA.
分子名称:Cell division protein FtsI/penicillin binding protein 2, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
著者CUFF, M., OSIPIUK, J., WU, R., ENDRES, M., JOACHIMIAK, A., Midwest Center for Structural Genomics (MCSG)
登録日2015-05-14
公開日2015-05-27
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Transpeptidase domain of FtsI4 D,D-transpeptidase from Legionella pneumophila.
to be published
5BP8
  • Download 5bp8
  • View 5bp8
Molmil generated image of 5bp8
ENT-COPALYL DIPHOSPHATE SYNTHASE FROM STREPTOMYCES PLATENSIS
分子名称:Ent-copalyl diphosphate synthase, SULFATE ION, 1,2-ETHANEDIOL
著者Osipiuk, J., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J.D., Ma, M., Chang, C.-Y., Shen, B., Joachimiak, A., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
登録日2015-05-27
公開日2015-06-10
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase.
J.Am.Chem.Soc., 138, 2016
5C0P
  • Download 5c0p
  • View 5c0p
Molmil generated image of 5c0p
THE CRYSTAL STRUCTURE OF ENDO-ARABINASE FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
分子名称:Endo-arabinase, MAGNESIUM ION, CHLORIDE ION, ...
著者Tan, K., Cuff, M., Joachimiak, G., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2015-06-12
公開日2015-07-01
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.532 Å)
主引用文献The crystal structure of endo-arabinase from Bacteroides thetaiotaomicron VPI-5482
To Be Published
5CR9
  • Download 5cr9
  • View 5cr9
Molmil generated image of 5cr9
CRYSTAL STRUCTURE OF ABC-TYPE FE3+-HYDROXAMATE TRANSPORT SYSTEM FROM SACCHAROMONOSPORA VIRIDIS DSM 43017
分子名称:ABC-type Fe3+-hydroxamate transport system, periplasmic component, MANGANESE (II) ION, ...
著者Nocek, B., Cuff, M., Mack, J., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2015-07-22
公開日2015-08-12
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of ABC-type Fe3+-hydroxamate transport system from Saccharomonospora viridis DSM 43017
To Be Published
5E7Q
  • Download 5e7q
  • View 5e7q
Molmil generated image of 5e7q
ACYL-COA SYNTHETASE PTMA2 FROM STREPTOMYCES PLATENSIS
分子名称:acyl-CoA synthetase, SULFATE ION, GLYCEROL
著者Osipiuk, J., Cuff, M.E., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J., Ma, M., Chang, C.Y., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2015-10-12
公開日2015-10-21
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.
Nat. Chem. Biol., 14, 2018
5F1P
  • Download 5f1p
  • View 5f1p
Molmil generated image of 5f1p
CRYSTAL STRUCTURE OF DEHYDROGENASE FROM STREPTOMYCES PLATENSIS
分子名称:PtmO8
著者Kim, Y., Li, H., Endres, M., Babnigg, G., Rudolf, J., Ma, M., Chang, C.-Y., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2015-11-30
公開日2015-12-30
最終更新日2017-02-22
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Crystal Structure of a Dehydrogenase, PtmO8, from Streptomyces platensis
To Be Published
5IXP
  • Download 5ixp
  • View 5ixp
Molmil generated image of 5ixp
CRYSTAL STRUCTURE OF EXTRACELLULAR SOLUTE-BINDING PROTEIN FAMILY 1
分子名称:Extracellular solute-binding protein family 1, FORMIC ACID
著者Chang, C., Cuff, M., Chhor, G., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2016-03-23
公開日2016-03-30
最終更新日2016-08-17
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure of Extracellular solute-binding protein family 1
To Be Published
5J7M
  • Download 5j7m
  • View 5j7m
Molmil generated image of 5j7m
CRYSTAL STRUCTURE OF CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN FROM KRIBBELLA FLAVIDA DSM 17836
分子名称:Cupin 2 conserved barrel domain protein, ETHANOL, NICKEL (II) ION, ...
著者Chang, C., Cuff, M., Chhor, G., Endres, M., Joachimiak, A.
登録日2016-04-06
公開日2016-04-27
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Crystal structure of Cupin 2 conserved barrel domain protein from Kribbella flavida DSM 17836
To Be Published
5UPQ
  • Download 5upq
  • View 5upq
Molmil generated image of 5upq
ACYL-COA SYNTHETASE PTMA2 FROM STREPTOMYCES PLATENSIS IN COMPLEX WITH SBNP465 LIGAND
分子名称:Acyl-CoA synthetase PtmA2, 5'-O-[(R)-{[(7beta,8alpha,9beta,10alpha,13alpha,16beta)-7,16-dihydroxy-18-oxokauran-18-yl]oxy}(hydroxy)phosphoryl]adenosine, SULFATE ION, ...
著者Osipiuk, J., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J.D., Chang, C.Y., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2017-02-03
公開日2017-02-22
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.
Nat. Chem. Biol., 14, 2018
5UPS
  • Download 5ups
  • View 5ups
Molmil generated image of 5ups
ACYL-COA SYNTHETASE PTMA2 FROM STREPTOMYCES PLATENSIS IN COMPLEX WITH SBNP663 LIGAND
分子名称:Acyl-CoA synthetase PtmA2, 5'-O-[(R)-hydroxy{[(7beta,8alpha,9beta,10alpha,11beta,13alpha)-7-hydroxy-19-oxo-11,16-epoxykauran-19-yl]oxy}phosphoryl]adenosine, SODIUM ION, ...
著者Osipiuk, J., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J.D., Chang, C.-Y., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2017-02-03
公開日2017-02-22
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.
Nat. Chem. Biol., 14, 2018
5UPT
  • Download 5upt
  • View 5upt
Molmil generated image of 5upt
ACYL-COA SYNTHETASE PTMA2 FROM STREPTOMYCES PLATENSIS IN COMPLEX WITH SBNP468 LIGAND
分子名称:Acyl-CoA synthetase PtmA2, (7alpha,8alpha,10alpha,13alpha)-7,16-dihydroxykauran-18-oic acid, SULFATE ION, ...
著者Osipiuk, J., Hatzos-Skintges, C., Endres, M., Babnigg, G., Rudolf, J.D., Chang, C.Y., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2017-02-03
公開日2017-02-22
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.
Nat. Chem. Biol., 14, 2018