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Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle
Descriptor:	Regulatory protein rop, ZINC ION
Authors:	Sagermann, M, Emery, S.C, Sander, C.
Deposit date:	2005-01-26
Release date:	2005-02-15
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle. To be Published

Structure of the Tie2 kinase domain in complex with a thiazolopyrimidine inhibitor
Descriptor:	2-[3-(CYCLOHEXYLMETHYL)-5-PHENYL-IMIDAZOL-4-YL]-[1,3]THIAZOLO[4,5-E]PYRIMIDIN-7-AMINE, ANGIOPOIETIN-1 RECEPTOR
Authors:	Brassington, C, Breed, J, Buttar, D, Fitzek, M, Forder, C, Hassall, L, Hayter, B.R, Jones, C.D, Luke, R.W.A, McCall, E, McCoull, W, Norman, R, Paterson, D, McMiken, H, Rowsell, S, Tucker, J.A.
Deposit date:	2009-08-18
Release date:	2009-11-03
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.95 Å)
Cite:	Novel Thienopyrimidine and Thiazolopyrimidine Kinase Inhibitors with Activity Against Tie-2 in Vitro and in Vivo. Bioorg.Med.Chem.Lett., 19, 2009